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testing the reproducibility and robustness of the cancer biology literature by robot

The Reproducibility Crisis – Robot Scientist ‘Eve’ Finds a Lack of...

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Scientists from the University of Cambridge have used a medley of automated text analysis and the 'robot scientist - Eve' to semi-automate the procedure...
Glyco-Decipher

Glyco-Decipher – A New Glycoproteomics Analysis Tool for Sensitive Deciphering of...

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A team of scientists led by Prof. YE Mingliang from the Dalian Institute of Chemical Physics (DICP) of the Chinese Academy of Sciences (CAS)...
Synaptic Integration in the Development of Deep Neural Networks

IBM Scientists Introduce Principles of Synaptic Integration in the Development of...

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The IBM Research - Zurich, scientists proposed a novel biologically-inspired optimizer for artificial and spiking neural networks that consolidate key standards of synaptic plasticity...
Source of Cell-to-Cell Variability in Cell Signallng

A Major Source of Cell-to-Cell Variability in Cell Signaling Dynamics Identified...

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To estimate cell-to-cell heterogeneity in non-Markovian signaling systems, mathematicians from The Korea Advanced Institute of Science and Technology (KAIST) and Institute for Basic Science...
Novel method to target potentially undiscovered beneficial therapeutic chemicals

Vanderbilt University Researchers have Developed a Novel Method to Target Potentially...

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A project coordinated by a group of researchers from the Eichman lab and the Evolutionary Studies Initiative on the research of chemical compounds produced...
Complete Human Genome Sequence T2T CHM13

Scientists Revealed the First Complete, Gapless Human Genome Sequence ‘T2T-CHM13’

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An international group of scientists has finally published the whole human genome sequence. The new reference genome fills in gaps left by previous versions,...
NRPS Complex

Tiny Bacterial Nonribosomal Peptide Synthetases Could Aid in the Development of...

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Researchers from McGill University collaborated with the Canadian Light Source (CLS) at the University of Saskatchewan to unlock the full potential of small biological...
New Improved Prime Editor in Plants to Produce Resistant and Improved Crops

Scientists Developed a New Improved Prime Editor in Plants to Produce Resistant and...

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Scientists from GAO Caixia's team at the Chinese Academy of Sciences' Institute of Genetics and Developmental Biology (IGDB) with collaborators have introduced Engineered Plant...
a new method AF2complex based on AlphaFold2 to predict protein complex structure and protein-protein interaction

A Deep Learning Model ‘AF2complex’ for Predicting Protein Complex Structures and...

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Scientists from the Center for the Study of Systems Biology, Atlanta, in collaboration with the Georgia Institute of Technology, Atlanta, and Oak Ridge National...
The landscape of receptor-mediated precision cancer combination therapy via a single-cell perspective

Scientists Discover the Landscape of Receptor-Mediated Precision Cancer Combination Therapy through...

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Scientists from the National Cancer Institute, Bethesda, and the University of Maryland have developed a computational tool to determine gene-target combinations for personalized cancer...
FORALL - acute lymphoblastic leukemia

A New Tool ‘FORALL’ for Profiling Multi-Omics and Drug Response in...

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In a report published in Nature Communications, researchers from the Department of Oncology-Pathology at Karolinska Institutet, Sweden established a cell line resource dataset and...
Whole-Genome Risk Prediction of Common Diseases

Scientists Design a Whole-Genome Risk Prediction of Common Diseases in the...

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Preimplantation genetic testing (PGT) of embryos fertilized in-vitro has been proposed as a strategy to diminish transmission of common diseases; in any case, a...
QBI Fear Gene resized

Scientists Discovered ‘Junk DNA’ as the Key to Controlling Fear

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Scientists from the University of Queensland found, a bit of "junk DNA" could be the key to eradicating fear-related memories in persons suffering from...
CellTreck

Scientists Developed a Computational Tool ‘CellTrek’ for Spatial Mapping of...

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'CellTrek' can accurately map single cells in diverse tissue types to resolve their spatial organization. The tool identifies the location of particular cell types...
A New Pathway through which tumor cells transfer genetic material to other cells in their microenvironment

Scientists Found a New Pathway Through Which Tumor Cells Transfer Genetic...

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Crislyn D'Souza-Schorey, the Morris Pollard Professor in the Department of Biological Sciences, and collaborators discovered that DNA "cargo" is transported in tiny informational sacs...
Biometric Identification of People By Heartbeat

Scientists Developed an Algorithm for Biometric Identification of People By their...

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According to a study undertaken by the Universidad Carlos III de Madrid (UC3M) and the Shahid Rajaee Teacher Training University of Iran, the heartbeat...
Antibody_Antigen

Scientists Develop a Model to Show How Antibodies Move Like a...

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A new study reveals how antibodies choose which antigens to bind to while navigating the surface of pathogens such as coronaviruses. Scientists from KTH...
REMI Algorithm

Advanced Algorithm REMI for Reconstruction of Codependent Cellular Interactions in Lung...

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Stanford University researchers have created a graph-based algorithm for reconstructing interactomes and identifying clinically important cell-cell interactions. The algorithm can be used to create...
Covid Severity Prediction Model

Scientists Developed a Hybrid Machine Learning/Deep Learning Based Covid-19 Severity Prediction...

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Scientists from Fondazione Poliambulanza Istituto Ospedaliero, Italy, developed a hybrid machine learning/deep learning model to classify patients in two outcome categories, non-ICU, and ICU....
ScType

Scientists from the University of Helsinki Developed a Computational Platform ‘ScType’...

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The researchers developed a computational platform ScType, which empowers a completely mechanized and super quick cell-type distinguishing proof-dependent exclusively upon given scRNA-seq information, alongside...
VARIABEL

Computer Scientists from Rice University Develop a Program ‘Variabel’ to Find...

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Variabel, a novel approach and first method designed for rescuing low frequency intra-host variants from Oxford Nanopore Technologies (ONT) data alone. Details about...
Model of human UMOD_FimH interaction_Jovine-custom20220311073044

A Perfect Trio of Crystallography, Cryo-EM and AlphaFold Reveals Information on...

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A team led by Karolinska Institutet used artificial intelligence (AI) and structural biology to learn more about two related proteins that protect the urinary...
'La Jolla Assembler (LJA)' to Scale-up Complete Genome Assembly

Scientists from the University of California Developed a Highly Accurate Algorithm...

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A team of international researchers led by the University of California San Diego's Department of Computer Science and Engineering has demonstrated that the La...
Single Test for Over 50 Genetic Diseases

Scientists at Garvan Institute Developed a Single Test for Over 50...

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Garvan Institute researchers have demonstrated how new genomic sequencing technologies might help individuals with uncommon neurological and neuromuscular conditions avoid a "diagnostic odyssey." - A...
Unique Lysin Capable of Killing Multidrug-Resistant Bacteria

A Unique Lysin Capable of Killing Multidrug-Resistant Bacteria Discovered by SMART...

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Antimicrobial activity of novel lysin Abp013 against Acinetobacter baumannii and Klebsiella pneumoniae has been demonstrated. Scientists from the Antimicrobial Resistance (AMR) Interdisciplinary Research Group at...
Total RNA-seq whole blood

Scientists from the University of Oxford Published Covid-19 Multi-omic Blood Atlas...

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In an integrated comparison with influenza and sepsis patients against healthy volunteers, the researchers show a complete multi-omic blood atlas for patients with different...
images_000044_bacteriacontent3.4

Different Bacteria Identified in Seconds with ‘Fingerprint’ Machine Learning Technique ​

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A platform for separation-free detection of bacteria in arbitrary medium has been developed by the researchers from Korea Advanced Institute of Science and Technology...
NeuTigersCOVID-Deep_012422_0011-2880x1920px

Scientists from Princeton University Developed Artificial Intelligence Based Smartwatch App ‘CovidDeep’...

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New software built by Princeton University researchers may determine whether someone is infected with COVID-19 in minutes by combining questions about a person's health...
Targeted Enzymes Destroy Viral RNA

Targeted Enzymes Knock Down Viral RNA

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The team of researchers led by the Technical University of Munich (TUM) was able to destroy the genetic code of SARS-CoV-2 by using particular...
multiscale-phate-pbmcs

Scientists from Yale University Developed a New Data Analysis Tool ‘Multiscale...

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Yale scientists report in the journal Nature Biotechnology this week that a novel data analysis technique they created has uncovered the particular immune cell...
atoms-ge2d3f2325_1920

Artificial Intelligence Algorithm Created for ‘Inverse Molecular Designing’ Determines Structure from...

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According to recent research published in  Nature Communications, a new AI algorithm creates novel compounds based on desired properties. Researchers are searching for innovative chemicals...
cardiometabolic_image

Population-Based Analysis of Over 200,000 People Displays Strong Genetic Relationship with...

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Researchers looked at data from over 200,000 people and discovered unusual genetic variations linked to diseases including diabetes and heart failure. Last year, the UK...
dna-sequence-1570578

Fastest DNA Sequencing that Uses AI and Accelerated Computing Sets Guinness...

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Stanford University researchers established the record in collaboration with NVIDIA, Oxford Nanopore Technologies, Google, Baylor College of Medicine, and the University of California, Santa...
Simulating Evolution

Simulating Directed Evolution With A New Computational Tool

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The researchers from Curtin University, Australia, and the University of Western Australia developed a system to carry out the complete process of directed evolution...
goblet-cells_cropped-294x300

Entire Human Gut Mapped by Scientists at the Single-Cell Resolution

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Scientists from the University of North Carolina School of Medicine, led by Scott Magness, Ph.D., sequenced the genes expressed in single cells from human...
Machine Learning to Predict Therapeutic Response in Gastric Cancer

Scientists Applied Machine Learning to Predict Therapeutic Response in Gastric Cancer

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The researchers at the Mayo Clinic Cancer Center in Florida, in a recent study published in Nature Communications, validate the use of genetic sequencing...
EmrE-TPP

Protein Structure of a Small Multidrug Resistance Transporter ‘EmrE’ Suggests the...

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A new research reveals how a protein removes harmful chemicals from bacterial cells. The structure of a protein that may pump hazardous chemicals out of...
mirror images to develop antibiotic resistance

Scientists Discover How Superbugs Employ Mirror Images To Develop Antibiotic Resistance

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Scientists from the Duke University with collaborators at the University of Connecticut are aiming to create novel enzyme inhibitors to combat Methicillin-resistant Staphylococcus aureus...
SLiMs_and_ENAH

Determining How Proteins Identify Their Binding Partners Inside Cells

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Scientists from MIT  probed into how proteins recognize and bind to one another, informing drug treatments for cancer. A single cell, despite its small size,...
INTEGRATE: a computational pipeline

INTEGRATE: A Computational Pipeline for Integrating Multi-Omics Data to Characterize Multi-Level...

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Scientists at The University of Milan-Bicocca, Milan, Italy, have proposed INTEGRATE, a computational pipeline that incorporates metabolomics and transcriptomics data, by applying constraint-based stoichiometric...
mouse-neurons-475x268-c-default

Machine Learning and Artificial Intelligence Based Study Helps Understand How Brain...

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Neurons are surprisingly complicated, for something so small, not only because there are billions of them in the brain but also because their function...
A Deep Learning Model for Predicting Tuberculosis Drug Resistance from Genomic Sequence Data may help in developing treatments against MTB.

Scientists Develop a Deep Learning Model for Predicting Tuberculosis Drug Resistance...

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The Researchers at The University of Chicago, Chicago, developed 24 binary classifiers of MTB drug resistance condition across eight anti-MTB drugs and three different...
Protein Switches

Scientists Discovered a New Protein Group that Serves Critical Function in...

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Researchers from Göttingen University have found a protein switch that controls enzymes in pathogens. An allosteric lysine–cysteine redox switch with a covalent NOS bridge...
Pink ribbon cancer sign on white

Artificial Intelligence Based Chemotherapy Response Prediction for Better and Personalized Breast...

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Scientists from the York University, Toronto, Canada, investigated a novel deep learning-based methodology to predict breast cancer response to neo-adjuvant chemotherapy (NAC) using the...
Examples of molecules generated by the contamination augmentation algorithm.

Image2SMILES – A Transformer Based Neural Network Model for Extracting Chemical...

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The researchers from Syntelly — a startup that originated at Skoltech — Lomonosov Moscow State University, and Sirius University present a Transformer-based artificial neural...
Dynamo - a computational tool for predicting cell fates and genetic perturbations.

Predicting Cell Fates and Genetic Perturbations with a New Computational Tool...

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The researchers from MIT Cambridge, USA, and collaborators at the University of Pittsburgh School of Medicine, present DYNAMO - an analytical framework that infers...
Scientists Have Discovered a New Process of Learning and Memory

Scientists Have Discovered a New Process Implicated in Learning and Memory

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Researchers from the Rockefeller University, United States revealed that FMRP, a protein that has been linked to fragile X syndrome, intellectual impairment, and some...
Examples of Spatial Mapping of Histone Modifications

Mapping the Development of Cell Types and Tissues

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Researchers at Yale University, in collaboration with Karolinska Institutet in Stockholm, Sweden, have created a technology that allows them to look at epigenetic mechanisms...
COVID-19 Phytochemical Drug Discovery

COVID-19 Phytochemical Drug Discovery with High-Resolution Computational Docking and Machine Learning...

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The researchers at Michigan State University in the United States used extensive structural datasets along with a refined and annotated collection of antiviral phytochemicals...
Virtual Screening of Ultra-Large Chemical Libraries Accelerated up to 100-Fold with Artificial Intelligence Enabled 'Deep Docking'

Virtual Screening of Ultra-Large Chemical Libraries Accelerated up to 100-Fold with...

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Deep Docking (DD) is artificial intelligence (AI) driven method that provides very economical yet highly reliable access to ultra-large docking. It was developed by...

Must Read

Computing the Human Interactome: A Deep Dive into Protein Interactions

Computing the Human Interactome: A Deep Dive into Protein Interactions

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A recent study by a team of researchers has made significant strides in unraveling this complex puzzle of human interaction. The human interactome encompasses...
Understanding FlexLMM: A Nextflow Framework for Genome-Wide Association Studies

Understanding FlexLMM: A Nextflow Framework for Genome-Wide Association Studies

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Genome-wide association Studies (GWAS) consider sequencing the DNA of a person and then comparing it with a population to find genetic markers associated with...
Meet metagWGS: A Flexible Workflow for Comprehensive Metagenomic Data Processing

Meet metagWGS: A Flexible Workflow for Comprehensive Metagenomic Data Processing

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An increasing number of studies employ metagenomic analyses to investigate the taxonomy and function of microorganism communities. In many microbial research, one typical job...
Cleveland Clinic and IBM Leverage AI to Revolutionize Drug Discovery for Pain Management

Cleveland Clinic and IBM Leverage AI to Revolutionize Drug Discovery for Pain Management

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In drug development, it isn't easy to learn molecular representation from chemical structures since traditional molecular representation techniques, such as sequence-based and graph-based approaches,...
The Protein Revolution: 2024 Nobel Prize in Chemistry Pioneers Protein Design and AI-Powered Predictions

The Protein Revolution: 2024 Nobel Prize in Chemistry Pioneers Protein Design and AI-Powered Predictions

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In a groundbreaking announcement that has sent ripples through the scientific community, the Royal Swedish Academy of Sciences has awarded the 2024 Nobel Prize...