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BioModME: A User-friendly Web Application for Building and Analyzing Biological Models

The complex processes that regulate biological systems have fascinated scientists for thousands of years. However, elucidating these complex issues sometimes requires thinking outside the...

Exploring the Boundless Frontiers of Biomolecular Modeling and Design with RoseTTAFold All-Atom

Models like AlphaFold2 (AF2) and RoseTTAFold, a modified structural biology tool, have not been able to replicate well the interactions or covalent changes with...

Prostate Cancer: Beyond One Disease? AI Uncovers Hidden Diversity

Prostate cancer remains a significant health threat for men globally. The development of cancer is an evolutionary process involving the sequential acquisition of genetic...

Decoding Genes and Cells with GenePT: A Simple Yet Powerful Foundation Model Leveraging ChatGPT

Large-scale gene expression data is used by Geneformer and scGPT models to build fundamental single-cell biology models. These models implicitly learn gene and cellular...

Unlocking Cellular Secrets: SCORPION’s Breakthrough in Population-level Comparisons of Gene Regulatory Networks

Gaining insight into the intricate workings of genes within cells is essential to comprehending biological processes and illnesses. Bulk RNA sequencing, which hides diversity...

Unveiling the Potential of RiNALMo: Advancing RNA Structure Prediction with General-Purpose RNA Language Models

Numerous fundamental functions of ribonucleic acid (RNA) are involved in basic biological processes. It is imperative that we deepen our comprehension of the structures...

Microsoft Reveals ViSNet: A Cutting-Edge Framework for Molecular Property Prediction and Simulating Molecular Dynamics

Molecular geometry modeling, which involves building models that show the spatial arrangement of atoms in a molecule, usually helps with this understanding. The field...

Revolutionizing Protein-Nucleic Acid Binding Prediction with PNAbind: A Graph Neural Network Approach

The geometric characteristics of protein-nucleic acid complexes, which are explored using structural models, are crucial for proteins to recognize and bind nucleic acids. However,...

ProLLaMA: A Multi-Tasking Protein Language Model Ushering in a New Era in Protein Science

The versatile workhorses of our cells, proteins, are essential to many biological processes. Numerous scientific endeavors, such as medication research and the creation of...

Unveiling PTM-Mamba: Revolutionizing Proteomics with PTM-Aware Protein Language Model

In living organisms, different types of proteins are essential for a variety of critical processes. The structural and functional diversity of many protein types...

Unraveling Genetic Mysteries with Proformer: A Hybrid Macaron Transformer Model

The ability to comprehensively decode the cis-regulatory logic that controls the expression values is made possible by the revolutionary high-throughput measurement of the cis-regulatory...

Meet GigaPevt: The Next-Gen Medical Assistant Powered by Multimodal AI

Building a smart and helpful me­dical assistant through AI is challenging. The healthcare industry has several obstacles, such as the increasing costs and shortage...

Eurofins Discovery Launches DiscoveryAI SAFIRE: A New AI Platform for Drug Discovery

The drug discovery process is unduly time-consuming and expensive. Extensive laboratory testing is required to evaluate potential drug candidates for absorption, distribution, metabolism, excretion,...

Can AI Assistants Crack Bioinformatics Challenges? A New Study Explores the Potential of Large Language Models

The scientific community may uncover the nature of life due to the great amount of biological data at its disposal. Implementing bioinformatics ensures converting...

From Molecules to Genomes: Evo’s Trailblazing Approach to Sequence Modeling and Design

The DNA, RNA, and proteins that control an organism's entire functioning are all fully encoded in a sequence called the genome. Large-scale genome databases...

PocketGen: A Novel Deep Generative Model for Designing Protein Binding Sites

The ability to accurately model and redesign ligand binding sites (pockets) on protein surfaces holds tremendous value across fields like drug discovery, enzyme engineering,...

Meet OncoGPT: Can This Medical Language Model Improve Communication and Support for Cancer Patients?

OncoGPT is a customized language model created by Shenzhen Kanghua Juntai Biotech Co. Ltd. researchers in China that is intended to deliver precise medical...

AlphaFLOW and ESMFLOW: A New Approach to Modeling Protein Ensembles with Combined Power of AlphaFold and Flow Matching

Dynamic structural ensembles play a major role in the biological functions of proteins. For the purpose of learning and sampling the conformational landscapes of...

Unlock the Potential of DeepMod2: A Deep Learning Framework for Precise DNA Methylation Analysis using Oxford Nanopore Sequencing

Reduced representation methylation sequencing for CpG islands or imprinted areas is made possible by Oxford Nanopore sequencing, which offers a distinct advantage over other...

Team of AI-made Scientists: A Groundbreaking System for Automating Scientific Discovery

Scientists from the University of Illinois, in collaboration with experts in the field, have unveiled a cutting-edge system named the "Team of AI-made Scientists."...

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Deciphering Ligand-Receptor Signaling Dynamics at Cellular Resolution with CytoSignal: A Breakthrough in Spatial Transcriptomics

Deciphering Ligand-Receptor Signaling Dynamics at Cellular Resolution with CytoSignal: A Breakthrough in Spatial Transcriptomics

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A thorough understanding of the cellular connections inside these tissues is being made possible by technologies that use spatial transcriptomic approaches to revolutionize the...
UnveilingProtLLM: The Next Generation Cross-Modal Large Language Model for Protein-Centric and Language Tasks

Unveiling PROTLLM: The Next Generation Cross-Modal Large Language Model for Protein-Centric and Language Tasks

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PROTLLM is a versatile crossmodal large language model (LLM) proposed by Beijing Institute of Technology researchers designed for protein-centric and protein-language tasks. It can handle...
Thousands of New Bile Acids Identified: A Major Discovery in Gut Microbiome Research

Thousands of New Bile Acids Identified: A Major Discovery in Gut Microbiome Research

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Bile acids, simple molecules that live in our intestines, have long been relegated to the role of digestive workhorses, faithfully emulsifying fats for absorption....
Basecamp Research Introduces BaseFold: A New Deep Learning Approach to Protein Structure Prediction

Basecamp Research Introduces BaseFold: A New Deep Learning Approach to Protein Structure Prediction

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Scaling laws predict the presence of over a trillion species on our planet. However, only a small fraction of them have been studied. Deep...
Unlocking the Microbial Universe: AllTheBacteria - Unparalleled Resource for Bacterial Genomics

Unlocking the Microbial Universe: AllTheBacteria – Unparalleled Resource for Bacterial Genomics

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DNA archives are a public repository for a great amount of knowledge about the evolution of bacteria and their mobile elements. However, the majority...