Bioinformatics is a rapidly growing field that blends biology, computer science, and data analysis to make sense of biological data. This field is growing...
Determining the function of proteins is one defining aspect of molecular biology that also carries great potential in drug discovery and development. A better...
The ability to anticipate the structure of proteins is essential for improving biological research, developing new pharmaceuticals, and designing experiments. It also helps to...
In a remarkable corridor of achievement, the scientists of the University of Southampton have reputedly gotten the ability to conserve the complete human genomic...
Target-based drug development depends heavily on characterizing druggable pockets, which are protein areas with the capacity to bind organic small molecules. Nevertheless, the process...
Clinical care as well as scientific research depend heavily on biomedical image segmentation. Certain biomedical picture segmentation tasks can be accurately automated by deep...
In a groundbreaking study published in Nature Methods, a group of scientists consisting of the UC Santa Cruz Genomics Institute, University of Ferrara, Google...
A notable progress in protein prediction and generative tasks, such as 3D structure prediction, protein design, and conformational dynamics, has been made in recent...
A recently published work by researchers from the Wuhan Textile University, China, and Michigan State University, USA, has addressed the use of transformer models...
One major obstacle in structure-based drug design is accurately predicting the affinities of protein-ligand interaction. The accuracy of data-driven affinity prediction methods has improved...
Numerous biological processes are regulated by protein-protein interactions (PPIs), and modified PPIs have uses in gene and cell therapy. Here, researchers from the University...
ChatMol, an innovative AI model designed by Tsinghua University, PingAn Technology, and Beijing University of Posts and Telecommunications researchers, shapes the contours of the...
Protein-binding protein computational design is a key skill with many applications in biotechnology and biological research. While some target proteins have been successfully targeted...
In a recent study published in Nature Communications, researchers at the University of Washington, University of California, San Francisco, and University of Michigan, along...
Enzymes can mediate discrete chemical reactions with sub-angstrom precision by employing complex, polar active sites to ensure a precise and effective response. Using the...
To fight cancer, we must stop their metastasis or uncontrolled multiplication. Hence, it is important to understand what proteins these cancer cells need for...
Proteins perform enormous tasks in our cells as molecular machines. These functions rely on the structural plasticity or the ability to adopt multiple shapes...
Rare events in proteins, which are essential for comprehending intricate phenomena like transitory structural changes and protein-ligand interactions, are frequently missed by unbiased molecular...
Researchers from Yale University and other institutions have identified MED6-189 as a new antimalarial drug, a new development that might change the dynamics of...
Making synthetic protein sequences from protein structures is a powerful use of protein engineering technology. It can be challenging to create designed proteins, though,...
Improved computational tools and artificial intelligence significantly improve drug discovery. This process has automated activities like molecular docking and predictive modeling to discover candidates...
The investigation of nuclear anomalies and how they influence the regulation of genes warrants analysis of various cellular functions and diseases. The researchers from...
Modeling of protein-small molecule systems offers advantages in speed and generality for exploring interactions with small molecules in the folded state; the modeling of...
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