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New Machine Learning Technique Predicts Cancer Patient Cure Rates More Accurately

As computing power has exponentially grown, machine learning (ML) techniques have gained immense popularity in healthcare - including predicting outcomes for patients with devastating...

UK Approves Revolutionary World-first Gene Editing Treatment for Blood Disorders

The UK has achieved a historic milestone by becoming the first country to authorize a revolutionary new treatment for two serious inherited blood conditions...

UCSD’s EUGENe: A New Deep Learning Toolkit to Decode the Regulatory Genome

Researchers at the University of California, San Diego, built EUGENe (elucidating the utility of genomic elements with neural nets) – an end-to-end Python toolkit...

Enlightening the Proteomic Space with Chroma: A Revolutionary Generative Model for Protein Design

Proteins are incredible molecules that carry out nearly every function necessary for life. However, their staggering complexity has made designing new proteins an immensely...

Unravel Cell-cell Communication with CellPhoneDB v5: A Cutting-edge Single-cell Multiomics Toolkit

We often underestimate the crucial role played by communications between cells to sustain living organisms. Flawless communication between cells is a necessity to maintain...

Unlocking the Secrets of Disease: The Imageable Genome and the Future of Molecular Medicine

Researchers at the University of Lucerne utilized molecular imaging to evaluate the expression of certain regions of the human genome. The imaging techniques are...

Demystifying Big Data with TBtools-II: A Versatile and Customisable All-in-One Platform for Bioinformatics Analysis

TBtools, a toolkit used for data analysis and bioinformatics tasks, was released in 2020 and quickly found a large audience – thousands of researchers...

Meet MiRGraph: A Novel Deep Learning Algorithm to Predict miRNA-target Interactions

A team of researchers from McGill University and Hunan University developed MiRGraph, a multi-view feature-learning method based on transformers that have the ability to...

Navigating the Complex Transcriptomic Landscape of Neurodegeneration with ZEBRA

Neurodegenerative diseases like Alzheimer's and Parkinson's remain poorly understood despite intensive research. While sequencing studies have profiled diverse brain cell populations, integrating findings into...

Meet A3D-MODB: A New Database for Predicting Protein Aggregation in Model Organisms

The Protein Folding and Computational Diseases Group at IBB-UAB, in collaboration with researchers from the University of Warsaw, developed a new database, A3D-MOBD (A3D...

Harnessing Artificial Intelligence to Decode Sudden Cardiac Death

Sudden cardiac death, the abrupt loss of heart function leading to mortality, accounts for up to 20% of passings globally. Despite being a major...

MIT’s iPGS: A New Inclusive Polygenic Scoring Model Revolutionizes Disease Risk Assessment for Diverse Populations

Massachusetts Institute of Technology (MIT) computer scientists developed iPGS, a model that gives accurate polygenic score calculations for the genetic makeup of individuals belonging...

DeepSA: A Cutting-edge Chemical Language Model for Compound Synthesis Accessibility Prediction

As computationally generated molecules become more popular in the fields of drug development and biotechnology, ease of synthesis becomes a common problem. Often, the...

EasyDock: A Scalable and User-friendly Tool for High-throughput Molecular Docking

Computational tools that are currently used for molecular docking are difficult to integrate into different computational distributions and interfaces; this becomes very inconvenient for...

Illuminating the Molecular Landscape of Disease with DiSignAtlas

Identifying the complex molecular changes underlying diverse diseases remains a grand challenge in biomedicine. While high-throughput omics technologies have enabled unbiased interrogation of disease...

Cellsnake: A New Tool Makes Single-cell RNA Sequencing Analysis Easier Than Ever

A collaborative effort between several medical departments at the University of Oslo led to the development of Cellsnake, a convenient tool for users to...

The AlphaFold Revolution Continues: Unraveling the Next-Gen Advancements

The introduction of AlphaFold 2 was a groundbreaking breakthrough in the field of predicting protein structures and interactions. Google's DeepMind, was the driving force...

Deep Learning Meets Clinical Microbiology: Unveiling DeepColony for Automated Culture Plates Interpretation

The introduction of Full Laboratory Automations has served to revolutionize the workflows of labs worldwide, helping with the automation of routine tasks and the...

Demystifying the Genetic Architecture of Proteins through Experimental Models

A collaborative effort between researchers from the UK, Spain, and Germany utilized experimental methods to explore amino acid sequence spaces and demonstrated that for...

Illuminating the Complexity of Interactions within and between Proteins and Ligands with Surfaces

Computational methods have revolutionized our understanding of molecular interactions and their pivotal role in the stability of biomolecular structures and complexes. These insights are...

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Decoding the Protein-Ligand Enigma: A Deep Dive into Deep Learning Approaches for Binding Affinity Prediction

Decoding the Protein-Ligand Enigma: A Deep Dive into Deep Learning Approaches for Binding Affinity...

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Researchers from the University of Oxford, UK, explore the impact of ligand and protein encodings on binding affinities prediction for different data sets, a...
A big picture look at the power of Genome LLMs.

Genome LLMs: Revolutionizing Genomics with Transformer-based Large Language Models

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Deep learning techniques have had a significant influence on genomics and the sequencing techniques employed in the field due to the exponential advancements in...
The Tail that Wiggles: A Reaction-Diffusion Model Unveils the Mechanism Behind Sperm Tail Movement

The Tail that Wiggles: A Reaction-Diffusion Model Unveils the Mechanism Behind Sperm Tail Movement

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The graceful, rhythmic beating of slender cellular appendages called flagella allows sperm cells and microorganisms like algae to swim. But how these waving motions...
Transforming Infection Diagnosis: Saliva-Based mRNA Biomarker for Accurate Detection

Transforming Infection Diagnosis: Saliva-Based mRNA Biomarker for Accurate Detection

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Since the COVID pandemic began, the world has been reminded of the poor reliability of elevated body temperature for detecting infections. Even when infected...
Meet NeuroVelo: A New Tool to Decode Cellular Dynamics from Single-cell Transcriptomic Data

Meet NeuroVelo: A New Tool to Decode Cellular Dynamics from Single-cell Transcriptomic Data

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A study conducted at the International School for Advanced Studies (SISSA) in Trieste, Italy, introduced NeuroVelo, a novel method tackling the challenge of reconstructing...