Scientists Develop a Deep Learning Model ‘CAESAR’ to Connect High-Resolution 3-Dimensional...
Researchers from the University of Michigan, USA, developed a deep learning model, CAESAR (Chromosomal structure And EpigenomicS AnalyzeR), to predict nucleosome-resolution 3D chromatin contact...
Single Cell RNA Sequencing Determines 16 Distinct Cell Populations in a...
The University of Alabama in Birmingham researchers have found 16 unique cell populations in a complex part of the midbrain known as the ventral...
Scientists Analyze the Promising Role of Prostate Cancer’s New Molecular Biomarkers:...
The scientists from Unidad de Investigación Biomédica en Cáncer, México, looked at numerous facets of prostate cancer, including new molecular markers linked to diagnosis,...
Engineered Bacteria Prevent Antibiotics from Harming the Beneficial Gut Microbes
Antibiotic-degrading microbes could help avoid opportunistic infections and reduce antibiotic resistance.
Antibiotic-induced changes in the gut microbiota have been linked to a variety of metabolic...
Protein Function and Properties Characterization Using Language Models
In recent years, deep learning algorithms have shown promise in identifying protein function and extracting complex sequence-structure-function correlations.
Scientists from Middle East Technical University and...
DGCyTOF: Deep Learning with Graphic Cluster Visualisation Model for Predicting Cell...
Researchers from The Ohio State University utilized deep-learning classification and hierarchical stable-clustering approaches to predict cell types from single-cell mass cytometry data. The DGCyTOF...
First Cell Transcriptomic Atlas of a Non-Human Primate Completed by an International...
Researchers from BGI-Research, in collaboration with scientific research teams from China, Germany, Italy, Singapore, Spain, Sweden, and the United Kingdom, published the world's first...
Machine Learning-Driven Antibiotic Selection Model that Predicts Personalized Antibiograms
The World Health Organization (WHO) appraises that 700,000 individuals now die yearly because of antibiotic resistance and anticipates that this number will surpass 10...
The Reproducibility Crisis – Robot Scientist ‘Eve’ Finds a Lack of...
Scientists from the University of Cambridge have used a medley of automated text analysis and the 'robot scientist - Eve' to semi-automate the procedure...
Glyco-Decipher – A New Glycoproteomics Analysis Tool for Sensitive Deciphering of...
A team of scientists led by Prof. YE Mingliang from the Dalian Institute of Chemical Physics (DICP) of the Chinese Academy of Sciences (CAS)...
IBM Scientists Introduce Principles of Synaptic Integration in the Development of...
The IBM Research - Zurich, scientists proposed a novel biologically-inspired optimizer for artificial and spiking neural networks that consolidate key standards of synaptic plasticity...
A Major Source of Cell-to-Cell Variability in Cell Signaling Dynamics Identified...
To estimate cell-to-cell heterogeneity in non-Markovian signaling systems, mathematicians from The Korea Advanced Institute of Science and Technology (KAIST) and Institute for Basic Science...
Vanderbilt University Researchers have Developed a Novel Method to Target Potentially...
A project coordinated by a group of researchers from the Eichman lab and the Evolutionary Studies Initiative on the research of chemical compounds produced...
Scientists Revealed the First Complete, Gapless Human Genome Sequence ‘T2T-CHM13’
An international group of scientists has finally published the whole human genome sequence. The new reference genome fills in gaps left by previous versions,...
Tiny Bacterial Nonribosomal Peptide Synthetases Could Aid in the Development of...
Researchers from McGill University collaborated with the Canadian Light Source (CLS) at the University of Saskatchewan to unlock the full potential of small biological...
Scientists Developed a New Improved Prime Editor in Plants to Produce Resistant and...
Scientists from GAO Caixia's team at the Chinese Academy of Sciences' Institute of Genetics and Developmental Biology (IGDB) with collaborators have introduced Engineered Plant...
A Deep Learning Model ‘AF2complex’ for Predicting Protein Complex Structures and...
Scientists from the Center for the Study of Systems Biology, Atlanta, in collaboration with the Georgia Institute of Technology, Atlanta, and Oak Ridge National...
Scientists Discover the Landscape of Receptor-Mediated Precision Cancer Combination Therapy through...
Scientists from the National Cancer Institute, Bethesda, and the University of Maryland have developed a computational tool to determine gene-target combinations for personalized cancer...
A New Tool ‘FORALL’ for Profiling Multi-Omics and Drug Response in...
In a report published in Nature Communications, researchers from the Department of Oncology-Pathology at Karolinska Institutet, Sweden established a cell line resource dataset and...
Scientists Design a Whole-Genome Risk Prediction of Common Diseases in the...
Preimplantation genetic testing (PGT) of embryos fertilized in-vitro has been proposed as a strategy to diminish transmission of common diseases; in any case, a...
Scientists Discovered ‘Junk DNA’ as the Key to Controlling Fear
Scientists from the University of Queensland found, a bit of "junk DNA" could be the key to eradicating fear-related memories in persons suffering from...
Scientists Developed a Computational Tool ‘CellTrek’ for Spatial Mapping of...
'CellTrek' can accurately map single cells in diverse tissue types to resolve their spatial organization. The tool identifies the location of particular cell types...
Scientists Found a New Pathway Through Which Tumor Cells Transfer Genetic...
Crislyn D'Souza-Schorey, the Morris Pollard Professor in the Department of Biological Sciences, and collaborators discovered that DNA "cargo" is transported in tiny informational sacs...
Scientists Developed an Algorithm for Biometric Identification of People By their...
According to a study undertaken by the Universidad Carlos III de Madrid (UC3M) and the Shahid Rajaee Teacher Training University of Iran, the heartbeat...
Scientists Develop a Model to Show How Antibodies Move Like a...
A new study reveals how antibodies choose which antigens to bind to while navigating the surface of pathogens such as coronaviruses. Scientists from KTH...
Advanced Algorithm REMI for Reconstruction of Codependent Cellular Interactions in Lung...
Stanford University researchers have created a graph-based algorithm for reconstructing interactomes and identifying clinically important cell-cell interactions. The algorithm can be used to create...
Scientists Developed a Hybrid Machine Learning/Deep Learning Based Covid-19 Severity Prediction...
Scientists from Fondazione Poliambulanza Istituto Ospedaliero, Italy, developed a hybrid machine learning/deep learning model to classify patients in two outcome categories, non-ICU, and ICU....
Scientists from the University of Helsinki Developed a Computational Platform ‘ScType’...
The researchers developed a computational platform ScType, which empowers a completely mechanized and super quick cell-type distinguishing proof-dependent exclusively upon given scRNA-seq information, alongside...
Computer Scientists from Rice University Develop a Program ‘Variabel’ to Find...
Variabel, a novel approach and first method designed for rescuing low frequency intra-host variants from Oxford Nanopore Technologies (ONT) data alone. Details about...
A Perfect Trio of Crystallography, Cryo-EM and AlphaFold Reveals Information on...
A team led by Karolinska Institutet used artificial intelligence (AI) and structural biology to learn more about two related proteins that protect the urinary...
Scientists from the University of California Developed a Highly Accurate Algorithm...
A team of international researchers led by the University of California San Diego's Department of Computer Science and Engineering has demonstrated that the La...
Scientists at Garvan Institute Developed a Single Test for Over 50...
Garvan Institute researchers have demonstrated how new genomic sequencing technologies might help individuals with uncommon neurological and neuromuscular conditions avoid a "diagnostic odyssey."
- A...
A Unique Lysin Capable of Killing Multidrug-Resistant Bacteria Discovered by SMART...
Antimicrobial activity of novel lysin Abp013 against Acinetobacter baumannii and Klebsiella pneumoniae has been demonstrated.
Scientists from the Antimicrobial Resistance (AMR) Interdisciplinary Research Group at...
Scientists from the University of Oxford Published Covid-19 Multi-omic Blood Atlas...
In an integrated comparison with influenza and sepsis patients against healthy volunteers, the researchers show a complete multi-omic blood atlas for patients with different...
Different Bacteria Identified in Seconds with ‘Fingerprint’ Machine Learning Technique
A platform for separation-free detection of bacteria in arbitrary medium has been developed by the researchers from Korea Advanced Institute of Science and Technology...
Scientists from Princeton University Developed Artificial Intelligence Based Smartwatch App ‘CovidDeep’...
New software built by Princeton University researchers may determine whether someone is infected with COVID-19 in minutes by combining questions about a person's health...
Targeted Enzymes Knock Down Viral RNA
The team of researchers led by the Technical University of Munich (TUM) was able to destroy the genetic code of SARS-CoV-2 by using particular...
Scientists from Yale University Developed a New Data Analysis Tool ‘Multiscale...
Yale scientists report in the journal Nature Biotechnology this week that a novel data analysis technique they created has uncovered the particular immune cell...
Artificial Intelligence Algorithm Created for ‘Inverse Molecular Designing’ Determines Structure from...
According to recent research published in Nature Communications, a new AI algorithm creates novel compounds based on desired properties.
Researchers are searching for innovative chemicals...
Population-Based Analysis of Over 200,000 People Displays Strong Genetic Relationship with...
Researchers looked at data from over 200,000 people and discovered unusual genetic variations linked to diseases including diabetes and heart failure.
Last year, the UK...
Fastest DNA Sequencing that Uses AI and Accelerated Computing Sets Guinness...
Stanford University researchers established the record in collaboration with NVIDIA, Oxford Nanopore Technologies, Google, Baylor College of Medicine, and the University of California, Santa...
Simulating Directed Evolution With A New Computational Tool
The researchers from Curtin University, Australia, and the University of Western Australia developed a system to carry out the complete process of directed evolution...
Entire Human Gut Mapped by Scientists at the Single-Cell Resolution
Scientists from the University of North Carolina School of Medicine, led by Scott Magness, Ph.D., sequenced the genes expressed in single cells from human...
Scientists Applied Machine Learning to Predict Therapeutic Response in Gastric Cancer
The researchers at the Mayo Clinic Cancer Center in Florida, in a recent study published in Nature Communications, validate the use of genetic sequencing...
Protein Structure of a Small Multidrug Resistance Transporter ‘EmrE’ Suggests the...
A new research reveals how a protein removes harmful chemicals from bacterial cells.
The structure of a protein that may pump hazardous chemicals out of...
Scientists Discover How Superbugs Employ Mirror Images To Develop Antibiotic Resistance
Scientists from the Duke University with collaborators at the University of Connecticut are aiming to create novel enzyme inhibitors to combat Methicillin-resistant Staphylococcus aureus...
Determining How Proteins Identify Their Binding Partners Inside Cells
Scientists from MIT probed into how proteins recognize and bind to one another, informing drug treatments for cancer.
A single cell, despite its small size,...
INTEGRATE: A Computational Pipeline for Integrating Multi-Omics Data to Characterize Multi-Level...
Scientists at The University of Milan-Bicocca, Milan, Italy, have proposed INTEGRATE, a computational pipeline that incorporates metabolomics and transcriptomics data, by applying constraint-based stoichiometric...
Machine Learning and Artificial Intelligence Based Study Helps Understand How Brain...
Neurons are surprisingly complicated, for something so small, not only because there are billions of them in the brain but also because their function...
Scientists Develop a Deep Learning Model for Predicting Tuberculosis Drug Resistance...
The Researchers at The University of Chicago, Chicago, developed 24 binary classifiers of MTB drug resistance condition across eight anti-MTB drugs and three different...
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45 Days Hands-on Skill Development Summer Training/Internship on “From Base Pairs to Big Data:...
Are you ready to transform your understanding of bioinformatics and gain hands-on experience with cutting-edge tools and technologies? The Centre of Bioinformatics Research & Technology...
Vision Transformers: A New Era in Protein-Ligand Affinity Prediction
Predicting how tightly a drug molecule (ligand) binds to its protein target is a cornerstone of modern drug discovery. Yet, this task remains a...
Building Better Models: How AI and Experimentation Shape GPCR Research in AlphaFold Era
The GPCR Dock competitions are a set of community-wide evaluations of ligand docking and computational structural modeling for G protein-coupled receptors, a key class...
Fast, Accurate, and Flexible: How FLOWR is Transforming Molecular Design
In a recent breakthrough in AI-driven drug discovery, researchers from Pfizer, AstraZeneca, and Chalmers University unveiled a new generative framework called FLOWR, designed to...
Designer Miniproteins: New Frontier in GPCR-Targeted Drug Development
G protein-coupled receptors (GPCRs) are essential membrane proteins with dynamic conformations that are also major targets for drug development and discovery. However, designing protein...