Friday, October 18, 2024
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Early Disease Diagnosis Using DNA Droplets

Scientists Develop a Novel Approach for Early Disease Diagnosis Using DNA...

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Scientists at Tokyo Tech have produced computational DNA droplets that can recognize specific patterns in tumor biomarker microRNA sequences by merging the technologies of...
Computer Simulation Coupled with Machine Learning Ravels the Mechanism of Cancer Drug Resistance.

A New Computer Simulation Coupled with Machine Learning Cracked the Mechanism...

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A team led by the University of Maryland utilizes machine learning to explain why a "wonder drug" may not work in all patients. Understanding how...
TrackMate v7 for Tracking Things in Bioimages

An Automated AI-Based Software ‘TrackMate v7’ for Tracking Things in Bioimages

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Scientists from Akademi University, Turku, Finland, and Pasteur Institute, Paris, France have developed a new software TrackMate v7 that may allow tracking things in...
How Protein Production is Regulated to Keep the Cells Healthy

Scientists Discover How Protein Production is Regulated to Keep the Cells...

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Scientists from Cold Spring Harbor Laboratory (CSHL) have discovered a key process which shows how protein production is regulated to keep the cells healthy....

PGDx Elio Tissue Complete – An Automated and FDA-Approved Clinical Genomics...

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PGDx Elio tissue complete, which the FDA has approved for the analysis of 505 cancer-related genes, will enable the development of more effective precision...
Small Peptide that Shows Huge Potential to Treat Antibiotic-Resistant Bacteria

Scientists Identify New Mechanism in Small Peptide that Shows Huge Potential...

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Scientists used neutrons to learn more about how aurein 1.2, an antimicrobial peptide (AMP) that attacks bacteria's membranes, kills antibiotic-resistant bacteria. The research will...

Scientists Employ RNA Velocity and Deep Learning to Study Gene Regulation...

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Scientists have developed DeepCycle, a deep learning approach combined with RNA velocity to reveal cell cycle gene regulation. This methodology is particularly appropriate to...
Hybrid Molecules by Drug Repurposing in an Effort to Design New Drugs to Treat Covid-19

Scientists Develop Hybrid Molecules by Drug Repurposing in an Effort to...

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Controlling the spread of the highly contagious disease and protecting human health requires developing new medications that stay effective against growing COVID-19 variations. After spending...
Blood Biomarker that can Predict Onset of Crohn’s Disease

Researchers Identify Blood Biomarker that can Predict Onset of Crohn’s Disease...

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A team led by the University of Toronto researcher discovered that a blood antibody can predict severe Crohn's disease up to seven years before...

Scientists Develop a Mathematical Model to Predict the Efficiency of Phage...

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Scientists from Inserm, Université Sorbonne Paris Nord, and Université Paris-Cité at the IAME Laboratory, with their collaborators at Institut Pasteur and the Paris Public...
Technological Advances in Drug Discovery

The Future of Medicine is Here: Top Tech Transforming Drug Discovery

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The advent of technological advances such as artificial intelligence (AI), machine learning (ML), automation, robotics, etc., has accelerated the pace of drug discovery as...
Monkeypox Virus Genome Sequence

First Draft of Monkeypox Virus Genome Sequenced from Current Outbreak Patient

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In a quest to understand why the monkeypox virus, which is a less lethal relative of smallpox, has infected so many people around the...
Machine Learning Algorithm uses Electronic Health Records to Predict Mental Health

Scientists Develop a Machine Learning Algorithm that uses Electronic Health Records...

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Scientists from Koa Health and Birmingham and Solihull Mental Health NHS Foundation Trust developed a machine learning model that uses electronic health records to...

Resistance Genes Identified can Predict Response to Arthritis Treatment and Lays...

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Researchers from the Queen Mary University of London have shown that molecular profiling of diseased joint tissue can significantly impact whether specific medication treatments...
BWA-MEME - Machine Learning-Based Short Read Alignment Algorithm to Speed up DNA Sequencing​

‘BWA-MEME’ – Machine Learning-Based Short Read Alignment Algorithm to Speed up...

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The algorithm is the first full-fledged machine learning-based short read alignment algorithm to speed up DNA sequencing,​ that efficiently uses learned indices to solve...
Smartphone-Powered Microchip for Medical Diagnostic Testing at Home

Researchers Introduce a Smartphone-Powered Microchip for Medical Diagnostic Testing at Home

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Researchers at the University of Minnesota developed a new microfluidic chip that can identify viruses, pathogens, bacteria, and other biomarkers in liquid samples. A...
Disease-Specific Host Gene-Microbiome Associations Across Human Diseases

Scientists Develop a Machine Learning-Based Framework to Identify Shared and Disease-Specific...

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Scientists from the University of Minnesota, Minneapolis, USA, with their collaborators, developed a machine learning framework for a multi-omic integration to identify the shared...
What is Bioinformatics?

What is Bioinformatics?

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Today's sequencing technologies are growing more advanced and producing larger and larger volumes of data in the range of exa- and zettabytes. Advanced algorithms...
CancerVar - A New Machine Learning Empowered Tool to Interpret Somatic Variants in Cancer

‘CancerVar’ – A New Machine Learning Empowered Tool to Interpret Somatic...

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CancerVar leverages machine learning frameworks to evaluate the potential relevance of somatic cancer mutations in terms of cancer diagnosis, prognosis, and targetability, in addition...
Enzyme Engineered by Structure-Based Machine Learning Degrades Plastic Waste

Enzyme Engineered by Structure-Based Machine Learning Degrades Plastic Waste in Hours...

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A team of scientists and engineers at the University of Texas at Austin created an enzyme that could break down environmentally damaging polymers in...
Structure of Key Protein in Cell Division

Researchers Puzzled by the Structure of Key Protein Implicated in Cell...

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Researchers from the Max Planck Institute reveal the first 3D image of the CCAN protein complex and highlight basic questions about the development of...
DeepRank-Data Mining ProteinProtein Interfaces Using 3D Convolutional Neural Networks

‘DeepRank’ – A Deep Learning Framework for Data Mining Protein-Protein Interfaces...

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Scientists formulate a deep learning framework, DeepRank, for the data mining of 3D protein-protein interfaces. They demonstrated the efficiency and readiness of DeepRank on...
Graph Neural Networks for Decoding Protein-Ligand Interactions

A Novel Parallel Graph Neural Networks Based Method for Decoding Protein-Ligand...

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A deep learning-based method for predicting the biophysical and biochemical features of protein-ligand complexes developed by researchers could help discover new drug candidates. Scientists formulate...
SARS-CoV-2 Delta Variant's Unique Binding Leads to High Transmissibility

SARS-CoV-2 Delta Variant’s Unique Binding Leads to High Transmissibility

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The National Institutes of Health's discovery could lead to new approaches to tackle future SARS-CoV-2 variants. According to a study by experts at the National...
Gut Microbiome and Antimicrobial Resistance

Impact of Antibiotics on the Evolution of Gut Microbiome and Antimicrobial...

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Following a single antibiotic course, the researchers discover how gut commensals acquire antimicrobial resistance genes (ARGs). According to the researchers, a single round of...
3D medical background with Covid 19 virus cells and blood cells

Scientists Revealed the Human Genetic Epidemiology of the COVID-19 Disease

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Scientists from the University of Helsinki, Broad Institute, and Harvard Medical School have revealed the human genetic epidemiology of the COVID-19 disease caused by...
Top 10 applications of Artificial Intelligence in healthcare

Top 10 Applications of Artificial Intelligence in Healthcare

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Top 10 Applications of Artificial Intelligence in Healthcare in 2022 and Beyond The healthcare industry has always been one of the leaders in using technology...
Smartphone App for Screening Neurological Disease at Home

A Smartphone App for Screening Neurological Disease at Home

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The RGB selfie camera and the front-facing near-infrared camera equipped for facial recognition can be used to capture an image of the eye. The...
Deep Neural Network Based 3D Reconstruction of Cellular Images to Track Real-Time Response of Tissues to Cancer Therapy

Deep Neural Network Based 3D Reconstruction of Cellular Images to Track...

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Microscopic imagers may be used in oncology to track and observe cell motions and dynamics, indicating tissues' real-time response to therapy. Scientists from the Department...
Chemical Wastes to Useful Drugs

Artificial Intelligence Based ‘Waste-to-Valuable’ Algorithm for Repurposing Chemical Wastes into Useful...

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The widespread use of computational waste-to-value algorithms can speed up the productive reuse of chemicals that would otherwise incur storage or disposal expenses or...
SINATRA Pro Computational Pipeline for for Discovery of Biophysical Signatures in Protein Dynamics

‘SINATRA Pro’ a Computational Pipeline for the Discovery of Biophysical Signatures...

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A group of scientists jointly proposed SINATRA Pro, a computational system for the extraction of key structural features between two sets of proteins. SINATRA...
Tool to Precisely Switch Gene Expression

​​Scientists Engineered a New Tool to Precisely Switch Gene Expression ‘On’...

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Scientists have developed a new approach for harnessing electrical signals to turn genes on and off. A team led by Imperial College London experts has...
Systems Genomics Approach to Identify Hidden Genetic Connections for Precision Medicine

A Systems Genomics Approach to Identify Hidden Genetic Connections for Precision...

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A new precision medicine tool 'iSNP' uncovers hidden genetic links that could enhance IBD and other difficult illnesses treatment. A group of scientists and clinicians...
FDA approved drug for SARS-CoV-2

Repurposing FDA Approved Asthma Drug to Block Crucial SARS-CoV-2 Protein

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In a new study by scientists from the Indian Institute of Science (IISc), repurposing a drug used to treat asthma and allergies has been...
Anti-Tuberculosis Treatment Drug Development

Benefits and Challenges of ‘One-Size-Fits-All’ Anti-Tuberculosis Treatment Strategies

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An expert scientist affiliated with the Center for Discovery and Innovation and a colleague from Harvard T.H. Chan School of Public Health discussed the...
CATCH Drug Molecules Targets

Scientists from Scripps Research Developed a New Technique ‘CATCH’ to Pinpoint...

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The new approach, developed by Scripps Research experts, has the potential to speed up the development of numerous novel drugs. Scripps Research scientists have developed...
blood test to determine if a pre-cancerous condition is progressing to malignancy

Scientists Discover a Sensitive Blood Test to Determine if a Pre-Cancerous...

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A test developed by OHSU researchers could help doctors treat cancer earlier when it's more likely to be cured. Scientists discover plasma cell-free RNA profiling,...
Machine Learning Model to Predict the Evolution of an Epidemic

Scientists Develop a Machine Learning Model to Predict the Evolution of...

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Machine learning algorithms can provide precise forecasting of virus propagation during pandemics. This method eliminates human bias and assumptions, allowing for a more accurate...

FDA-Approved Drugs Repurposing for Treating Alzheimer’s Disease using Hierarchical Cluster Analysis...

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Scientists from Brown University identified the novel usage of FDA-approved drugs by cluster analysis of behavioral profiles for the treatment of neurodegenerative disorders by...
Artificial Intelligence Enables Physicians to Better Evaluate the Effectiveness of Bladder Cancer Treatment

Artificial Intelligence Enables Physicians to Better Evaluate the Effectiveness of Bladder Cancer...

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Consultation with a machine learning tool helped providers determine more accurately whether patients had a complete response to chemotherapy. Scientists from the University of Michigan...
BioCRNpyler - A Python Package to Build Manage and Explore Intricate Biochemical Models

‘BioCRNpyler’ – A Python Package to Build, Manage and Explore Intricate...

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Scientists from the California Institute of Technology, United States, have developed a python package, 'BioCRNpyler', to build, manage, and explore intricate biochemical models. BioCRNpyler...
breast cancer recurrence

Scientists Identify New Factors that Can Predict Breast Cancer Recurrence

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Scientists at Georgetown Lombardi Comprehensive Cancer Center have uncovered genetics and other characteristics that can predict if a woman is at risk of breast...
Deep Learning Model Epigenomics

Scientists Develop a Deep Learning Model ‘CAESAR’ to Connect High-Resolution 3-Dimensional...

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Researchers from the University of Michigan, USA, developed a deep learning model, CAESAR (Chromosomal structure And EpigenomicS AnalyzeR), to predict nucleosome-resolution 3D chromatin contact...
Single Cell RNA Sequencing

Single Cell RNA Sequencing Determines 16 Distinct Cell Populations in a...

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The University of Alabama in Birmingham researchers have found 16 unique cell populations in a complex part of the midbrain known as the ventral...
Artificial Intelligence in Prostate Cancer Research

Scientists Analyze the Promising Role of Prostate Cancer’s New Molecular Biomarkers:...

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The scientists from Unidad de Investigación Biomédica en Cáncer, México, looked at numerous facets of prostate cancer, including new molecular markers linked to diagnosis,...
Antibiotics Gut Microbes

Engineered Bacteria Prevent Antibiotics from Harming the Beneficial Gut Microbes

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Antibiotic-degrading microbes could help avoid opportunistic infections and reduce antibiotic resistance. Antibiotic-induced changes in the gut microbiota have been linked to a variety of metabolic...
Protein Function

Protein Function and Properties Characterization Using Language Models

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In recent years, deep learning algorithms have shown promise in identifying protein function and extracting complex sequence-structure-function correlations.  Scientists from Middle East Technical University and...
DGCyTOF model - single-cell mass cytometry

DGCyTOF: Deep Learning with Graphic Cluster Visualisation Model for Predicting Cell...

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Researchers from The Ohio State University utilized deep-learning classification and hierarchical stable-clustering approaches to predict cell types from single-cell mass cytometry data. The DGCyTOF...
Generation-of-a-cell-atlas-across-45-tissues-of-adult-M. fascicularis-monkey

First Cell Transcriptomic Atlas of a Non-Human Primate Completed by an International...

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Researchers from BGI-Research, in collaboration with scientific research teams from China, Germany, Italy, Singapore, Spain, Sweden, and the United Kingdom, published the world's first...
Optimizing-antibiotic-selections-with-linear-programming

Machine Learning-Driven Antibiotic Selection Model that Predicts Personalized Antibiograms 

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The World Health Organization (WHO) appraises that 700,000 individuals now die yearly because of antibiotic resistance and anticipates that this number will surpass 10...

Must Read

Computing the Human Interactome: A Deep Dive into Protein Interactions

Computing the Human Interactome: A Deep Dive into Protein Interactions

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A recent study by a team of researchers has made significant strides in unraveling this complex puzzle of human interaction. The human interactome encompasses...
Understanding FlexLMM: A Nextflow Framework for Genome-Wide Association Studies

Understanding FlexLMM: A Nextflow Framework for Genome-Wide Association Studies

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Genome-wide association Studies (GWAS) consider sequencing the DNA of a person and then comparing it with a population to find genetic markers associated with...
Meet metagWGS: A Flexible Workflow for Comprehensive Metagenomic Data Processing

Meet metagWGS: A Flexible Workflow for Comprehensive Metagenomic Data Processing

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An increasing number of studies employ metagenomic analyses to investigate the taxonomy and function of microorganism communities. In many microbial research, one typical job...
Cleveland Clinic and IBM Leverage AI to Revolutionize Drug Discovery for Pain Management

Cleveland Clinic and IBM Leverage AI to Revolutionize Drug Discovery for Pain Management

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In drug development, it isn't easy to learn molecular representation from chemical structures since traditional molecular representation techniques, such as sequence-based and graph-based approaches,...
The Protein Revolution: 2024 Nobel Prize in Chemistry Pioneers Protein Design and AI-Powered Predictions

The Protein Revolution: 2024 Nobel Prize in Chemistry Pioneers Protein Design and AI-Powered Predictions

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In a groundbreaking announcement that has sent ripples through the scientific community, the Royal Swedish Academy of Sciences has awarded the 2024 Nobel Prize...