Scientists Develop a Novel GPU-based Machine Learning Model to Discover Human...
Indian Institute of Science (IISc) researchers have created a novel GPU-based machine learning model to better understand and predict human brain connections across various...
Single-Cell Map of Heart Failure Provides Insights into Novel Potential Therapeutic...
Researchers have discovered molecular fingerprints that lead to biological causes of disease by analyzing individual cardiac cells from heart failure patients.
Heart failure is an...
TAS-Seq – A New Sensitive, and Powerful Single-Cell RNA Sequencing Technique...
The emergence of single-cell RNA sequencing (scRNA-seq) has now made it possible to analyze the internal workings of hundreds of cells at once, revolutionizing...
PICASSO Technique Helps Scientists Visualize Biological Molecules into Technicolor
Scientists from the Korea Advanced Institute of Science and Technology propose the PICASSO technique, which enables more than 15-color imaging of spatially overlapping proteins...
High-Resolution Cryo-EM Structure of Type IV Secretion System Offers New Hope...
A group of researchers from UCL and Birkbeck has discovered a novel strategy to help limit the spread of antibiotic resistance, which has the...
Applying 3D Computational Simulation to Reveal the Secrets of the Genome...
A research team from Nagoya University in Japan has created a 3-Dimensional computational simulation of the formation of the genome structure in the human...
Scientists Integrate Genome Mining with PAN Genome Analysis to Discover the...
Scientists from the Technical University of Denmark (DTU) and the University of California San Diego present a systems biology workflow that integrates genome mining...
Scientists Unravel How DNA Double Helix Structure is Opened to Allow...
Scientists at the Francis Crick Institute have uncovered how the DNA double helix structure is opened to allow DNA replication. The research could pave...
Scientists Discover a New Mechanism for Endoplasmic Reticulum Sorting of LRR...
Scientists from the Chinese Academy of Sciences' Institute of Genetics and Developmental Biology (IGDB) have discovered a new mechanism that protects the endoplasmic reticulum...
Scientists Develop Structural 3D Maps of Key Proteins that Go Wrong...
Cold Spring Harbor Laboratory (CSHL) scientist Professor Hiro Furukawa adopts an architectural approach to brain research. He makes structural 3D maps of key proteins...
Scientists Used a Netflix-Style Algorithm to Create Blueprint of Cancer Genomes
The algorithms that track users' Netflix viewing habits could soon be used to track cancer development in order to direct doctors in managing cancer.
An...
Supercomputing Helps Discover Weaknesses in HIV-1 Virus Capsid
There's still a lot to discover about how the HIV-1 virus affects human cells. Scientists believe it gets past our immune system's defenses and...
Repurposing Progesterone Altering Drug to Diminish the Risk of Severe Triple...
According to new research headed by University College London experts existing drugs that affect the impact of the hormone progesterone, such as mifepristone, have...
Disease Prognosis Using Deep Learning and H&E Images – Emerging Tool...
Scientists used hematoxylin and eosin (H&E) images with a deep learning approach to predict disease outcomes, an emerging technique for the improvement of clinical trials...
Scientists Develop a New Computational Tool ‘Grit’ to Identify Upstream Transcription...
Scientists from Yangtze University, Jingzhou, China developed a computational tool, "Grit," to identify the upstream transcription factor binding sites in orthologous genes by the...
Scientists Elucidate How Bacteria Communicate Their Way To Causing Infection
Scientists at Oregon State University revealed how bacteria communicate their way to causing infection. The researchers discovered proteins that prevent a bacterial cell from...
Scientists Synthesize a New Molecule with the Ability to Kill a...
Scientists have developed ERX-41, a potent therapeutic drug with a well-defined molecular target (Lysosomal Acid Lipase, LAL) and mechanism of action (disruption of protein...
Transcriptome-Wide Association Studies Integrated with 3D Genomic and Epigenomic Data used...
Scientists from Pennsylvania State University integrated 3D genomic and epigenomic data with transcriptome-wide association studies data to improve gene expression predictions.
The researchers propose an integrative method...
Scientists Use CRISPR Technology and Perturb-seq to Map Every Human Gene...
Scientists from Whitehead Institute and collaborators used Perturb-seq, a single-cell sequencing technology, to link every expressed gene in the human genome to its function...
Scientists Develop a Novel Probabilistic Generative Model ‘RaptGen’ for Aptamer Generation
Scientists from the Graduate School of Advanced Science and Engineering at Waseda University, Japan, developed RaptGen, a variational autoencoder for in silico aptamer generation....
Scientists Develop a New Computer Vision Model with Improved Proficiency to...
Hospital for Special Surgery (HSS) researchers in New York City have developed a computer vision tool that effectively identifies rheumatoid arthritis (RA) from osteoarthritis...
Scientists Discover Superbug Develops Drug-Resistance to ‘last Resort’ Antibiotic Fast
New research from University of Oxford revealed that superbug Pseudomonas develops resistance to a common 'last-resort' antibiotic much faster than expected.
Recent research published in Cell Reports...
ColabFold: A Freely Accessible Protein Folding Tool for Accelerated Prediction of...
Scientists have developed ColabFold, an open-source software to accelerate the prediction of protein structures as well as complexes by integrating fast homology search of...
Scientists Discover New Mass Spectrometry-Based Proteomics Method For Early Detection of...
Through mass spectrometry-based proteomics, a German-Danish research team led by Matthias Mann has developed a new screening tool to identify alcohol-related liver disorders at...
Scientists Develop a Novel Approach for Early Disease Diagnosis Using DNA...
Scientists at Tokyo Tech have produced computational DNA droplets that can recognize specific patterns in tumor biomarker microRNA sequences by merging the technologies of...
A New Computer Simulation Coupled with Machine Learning Cracked the Mechanism...
A team led by the University of Maryland utilizes machine learning to explain why a "wonder drug" may not work in all patients.
Understanding how...
An Automated AI-Based Software ‘TrackMate v7’ for Tracking Things in Bioimages
Scientists from Akademi University, Turku, Finland, and Pasteur Institute, Paris, France have developed a new software TrackMate v7 that may allow tracking things in...
Scientists Discover How Protein Production is Regulated to Keep the Cells...
Scientists from Cold Spring Harbor Laboratory (CSHL) have discovered a key process which shows how protein production is regulated to keep the cells healthy....
PGDx Elio Tissue Complete – An Automated and FDA-Approved Clinical Genomics...
PGDx Elio tissue complete, which the FDA has approved for the analysis of 505 cancer-related genes, will enable the development of more effective precision...
Scientists Identify New Mechanism in Small Peptide that Shows Huge Potential...
Scientists used neutrons to learn more about how aurein 1.2, an antimicrobial peptide (AMP) that attacks bacteria's membranes, kills antibiotic-resistant bacteria. The research will...
Scientists Employ RNA Velocity and Deep Learning to Study Gene Regulation...
Scientists have developed DeepCycle, a deep learning approach combined with RNA velocity to reveal cell cycle gene regulation. This methodology is particularly appropriate to...
Scientists Develop Hybrid Molecules by Drug Repurposing in an Effort to...
Controlling the spread of the highly contagious disease and protecting human health requires developing new medications that stay effective against growing COVID-19 variations.
After spending...
Researchers Identify Blood Biomarker that can Predict Onset of Crohn’s Disease...
A team led by the University of Toronto researcher discovered that a blood antibody can predict severe Crohn's disease up to seven years before...
Scientists Develop a Mathematical Model to Predict the Efficiency of Phage...
Scientists from Inserm, Université Sorbonne Paris Nord, and Université Paris-Cité at the IAME Laboratory, with their collaborators at Institut Pasteur and the Paris Public...
The Future of Medicine is Here: Top Tech Transforming Drug Discovery
The advent of technological advances such as artificial intelligence (AI), machine learning (ML), automation, robotics, etc., has accelerated the pace of drug discovery as...
First Draft of Monkeypox Virus Genome Sequenced from Current Outbreak Patient
In a quest to understand why the monkeypox virus, which is a less lethal relative of smallpox, has infected so many people around the...
Scientists Develop a Machine Learning Algorithm that uses Electronic Health Records...
Scientists from Koa Health and Birmingham and Solihull Mental Health NHS Foundation Trust developed a machine learning model that uses electronic health records to...
Resistance Genes Identified can Predict Response to Arthritis Treatment and Lays...
Researchers from the Queen Mary University of London have shown that molecular profiling of diseased joint tissue can significantly impact whether specific medication treatments...
‘BWA-MEME’ – Machine Learning-Based Short Read Alignment Algorithm to Speed up...
The algorithm is the first full-fledged machine learning-based short read alignment algorithm to speed up DNA sequencing, that efficiently uses learned indices to solve...
Researchers Introduce a Smartphone-Powered Microchip for Medical Diagnostic Testing at Home
Researchers at the University of Minnesota developed a new microfluidic chip that can identify viruses, pathogens, bacteria, and other biomarkers in liquid samples.
A...
Scientists Develop a Machine Learning-Based Framework to Identify Shared and Disease-Specific...
Scientists from the University of Minnesota, Minneapolis, USA, with their collaborators, developed a machine learning framework for a multi-omic integration to identify the shared...
What is Bioinformatics?
Today's sequencing technologies are growing more advanced and producing larger and larger volumes of data in the range of exa- and zettabytes. Advanced algorithms...
‘CancerVar’ – A New Machine Learning Empowered Tool to Interpret Somatic...
CancerVar leverages machine learning frameworks to evaluate the potential relevance of somatic cancer mutations in terms of cancer diagnosis, prognosis, and targetability, in addition...
Enzyme Engineered by Structure-Based Machine Learning Degrades Plastic Waste in Hours...
A team of scientists and engineers at the University of Texas at Austin created an enzyme that could break down environmentally damaging polymers in...
Researchers Puzzled by the Structure of Key Protein Implicated in Cell...
Researchers from the Max Planck Institute reveal the first 3D image of the CCAN protein complex and highlight basic questions about the development of...
‘DeepRank’ – A Deep Learning Framework for Data Mining Protein-Protein Interfaces...
Scientists formulate a deep learning framework, DeepRank, for the data mining of 3D protein-protein interfaces. They demonstrated the efficiency and readiness of DeepRank on...
A Novel Parallel Graph Neural Networks Based Method for Decoding Protein-Ligand...
A deep learning-based method for predicting the biophysical and biochemical features of protein-ligand complexes developed by researchers could help discover new drug candidates.
Scientists formulate...
SARS-CoV-2 Delta Variant’s Unique Binding Leads to High Transmissibility
The National Institutes of Health's discovery could lead to new approaches to tackle future SARS-CoV-2 variants.
According to a study by experts at the National...
Impact of Antibiotics on the Evolution of Gut Microbiome and Antimicrobial...
Following a single antibiotic course, the researchers discover how gut commensals acquire antimicrobial resistance genes (ARGs). According to the researchers, a single round of...
Scientists Revealed the Human Genetic Epidemiology of the COVID-19 Disease
Scientists from the University of Helsinki, Broad Institute, and Harvard Medical School have revealed the human genetic epidemiology of the COVID-19 disease caused by...
Must Read
Innovating Through Collaboration: The Protein Engineering Tournament’s Impact on Computational Design
Protein engineering heavily relies on generating sequences using computational models. Limitations such as lack of benchmarking opportunities, scarcity of large protein function datasets, and...
How BALM is Redefining Binding Affinity Prediction for Unseen Targets and Drugs
In the fast-paced world of drug discovery, one of the most crucial aspects is understanding protein-ligand interactions. With the correct algorithms for predicting protein-ligand...
EPBDxDNABERT-2: A Multi-Modal Deep Learning Model for Enhanced Transcription Factor DNA Binding Prediction
It has been demonstrated that there is a functional correlation between transcriptional activity, thermodynamic stability, DNA breathing, and transcription factor (TF) binds. The researchers...
Omega-3 and Omega-6 Fatty Acids: New Allies in Cancer Prevention
A groundbreaking new research from the University of Georgia unveils that omega-3 and omega-6 fatty acids may play an integral role in cancer prevention,...
The Future of Bioinformatics: Building Expertise for Data-Driven Discovery
In an era where biological data grows exponentially, bioinformatics has emerged as a vital interdisciplinary field that combines biology, computer science, mathematics, and statistics....