EMBL’s Scientists Modeled Molecular Complexes Inside Cells at Atomic Resolution Using...
To better comprehend the function of cells, scientists examine how different components of a cell – from single molecules to several organelles – work...
‘Valves in DNA’ Created to Shape the Flow of Biological Information
New biological components developed by scientists at the University of Bristol can alter the flow of cellular activities along DNA.
The scientists provide new insights...
‘Lab on a Chip’ for Measuring Protein-DNA Interactions
Cornell researchers have invented new nanophotonic tweezers that can fit on a smaller than one-inch square chip, making it easier and more efficient to...
Genome-Scale Protein Structure and Function Prediction with High-Performance Computing Toolkit
A group of scientists from the Department of Energy's Oak Ridge National Laboratory (ORNL) and the Georgia Institute of Technology applied supercomputing and new...
Modeling Protein Fitness Using Evolutionary and Assay-Labeled Data
Scientists from the University of California, Berkeley have developed a machine learning-based model that predicts protein fitness from the sequence.
Protein fitness is a broad...
iDIRECT – A Framework for Analyzing Network Interactions in Various...
Scientists from the University of Oklahoma and University of California at Berkeley have developed a framework iDIRECT (Inference of Direct and Indirect Relationships with...
Structure Modeling with a New Method Mapped 500 Previously Unsolved Proteins
Pathogens employ virulence factors called effectors, which are critical for their survival. Homology modeling is one of the most extensively used approaches; however, it...
The Earth BioGenome Project Steadily Started Sequencing Genomes
A worldwide endeavor to map the genomes of all life on Earth (plants, animals, fungi, and other microbes) is entering a new phase as...
Nanoantenna – The World’s Smallest Antenna Created Using DNA to Monitor...
A new DNA-based fluorescent nanoantenna is created by getting inspired by the ‘Lego-like’ properties of DNA. The building blocks of the new nanoantenna are...
Scientists Develop a Model Based on Artificial Intelligence to Predicts Risk...
The PET/CT artificial intelligence model performed better than clinical data in predicting heart attack risk in individuals with established coronary artery disease.
Predicting a heart...
Metagenomics of Human Skin Microbiome Identifies New Bacteria and Viruses
Scientists from EMBL-EBI, NIH, NHGRI, and collaborators have discovered new micro-organisms (bacterial, fungal species, and viruses) in the human skin microbiome.
The human skin microbiome...
Deep Learning Based DNA and RNA Binding Sites Prediction for Accelerated...
Targeting nucleic acid macromolecules, particularly RNA, for structure-based drug design (SBDD) is gaining research attention as it resulted in several FDA-approved compounds targeting RNA...
Multi-omics Data Visualization and Chromosomes Annotation with an R Package “ChromoMap”
ChromoMap is a fast and easy-to-use tool for visualizing genomic elements and related data (such as multi-omics data) in relation to their chromosome-by-chromosome occurrence...
Early Stage Bronchial Asthma Diagnosis with Artificial Intelligence
Scientists from Ben-Gurion University, Israel, have developed a method for computer-aided diagnostics of bronchial asthma based on machine learning. The model is trained using...
Pregnancy Health and Preeclampsia Prediction Using RNA Sequencing from a Single...
Using cell-free RNA (cfRNA), researchers discovered gene expression patterns linked to a healthy pregnancy.
Conception to birth is a fast-paced period of growth and development...
AI Driven Analysis of Cell Diversity in Drosophila melanogaster Brain
The research published in Nature combines single-cell technologies and artificial intelligence (AI) to create a new picture of gene regulation in all the fruit...
Transforming DNA-Repair Visualization by Machine Learning Coupled High-Throughput Microscopy
Machine learning may aid in repairing genetic damage and avoiding DNA mutations and chronic diseases.
Scientists from Massachusetts General Hospital and the National Cancer Research...
Evaluating gene expression in single cells with a novel computational approach...
By inventing and deploying a novel single-cell sequencing technique that potentially improves upon those already in use, researchers at the University of Chicago Medicine...
spiralize: R package to visualize data on spirals
For data visualization, the spiral arrangement offers two significant advantages. Firstly, data with long axes can be visualized, enhancing visualization resolution. Secondly, time-series data...
Antibodies that can block Omicron variant of Covid-19 identified
Antibodies have been found that neutralize Omicron and other coronavirus strains by targeting areas that stay largely unchanged as the virus mutates have been...
Cryobioprinting a technique for printing frozen and complex structures uses bioink...
A newly introduced technique takes bioprinting -; where the ink of cells does printing, layer by layer, forming a structure -; to a whole...
Predicting Gene Expression From DNA Sequence Using AI
Interpreting gene expression from the DNA sequence is one of the most challenging problems in genome biology. Decoding DNA sequence with the help of...
SARS-CoV-2 Mechanism of Evading Immune System Revealed
The mechanism used by SARS-CoV-2 to escape the host immune system has been revealed by scientists from Hokkaido University, Japan and Texas A&M University,...
Must Read
Solving a Long-Standing Genomics Bottleneck: KAIST Proposes AI-Powered Strategy for Gene Function Prediction
KAIST and UCSD researchers proposed AI-driven strategies for microbial gene function discovery, addressing the long-standing bottleneck where many microbial genes remain uncharacterized despite advances...
AI-Powered Metagenomics: How MetagenBERT Predicts Disease From Raw DNA Sequences
Researchers from Sorbonne University and Dauphine University, France, introduced MetagenBERT, a Transformer-based framework for disease prediction directly from raw metagenomic DNA without relying on...
ToposBio Unveils Topos-1: An All-Atom Foundation Model for Intrinsically Disordered Proteins
Intrinsically disordered proteins (IDPs) are proteins that are central to neurodegenerative diseases and aggressive cancers like prostate cancer, have been considered ‘undruggable’ as structures...
CleaveNet Enables Scalable and Targeted Protease Substrate Design for Diagnostics and Therapeutics
Scientists from MIT and Microsoft Research present CleaveNet, an AI-based pipeline that merges predictive and generative modeling for end-to-end peptide (short protein) design. By...
Advancing Peptide Therapeutics with PeptiVerse’s Unified Prediction Framework
Researchers at the University of Pennsylvania developed PeptiVerse, a single platform that predicts drug-related properties of therapeutic peptides using either amino acid sequences or...