Thursday, May 26, 2022
Scientists from Inserm, Université Sorbonne Paris Nord, and Université Paris-Cité at the IAME Laboratory, with their collaborators at Institut Pasteur and the Paris Public Hospitals Group (AP-HP), develop an in silico model in combination with in vivo phage therapy...
Following a single antibiotic course, the researchers discover how gut commensals acquire antimicrobial resistance genes (ARGs). According to the researchers, a single round of antibiotics may be enough to drive ARG acquisition and occurrence in gut commensals throughout the...
The widespread use of computational waste-to-value algorithms can speed up the productive reuse of chemicals that would otherwise incur storage or disposal expenses or even pose environmental risks. Scientists from the Ulsan Institute of Science and Technology, Republic of Korea,...
An expert scientist affiliated with the Center for Discovery and Innovation and a colleague from Harvard T.H. Chan School of Public Health discussed the challenges and priorities in the anti-tuberculosis treatment strategies and drug development. The study published in Nature...
Antibiotic-degrading microbes could help avoid opportunistic infections and reduce antibiotic resistance. Antibiotic-induced changes in the gut microbiota have been linked to a variety of metabolic and inflammatory illnesses, as well as an increased risk of subsequent infections and the development...
The World Health Organization (WHO) appraises that 700,000 individuals now die yearly because of antibiotic resistance and anticipates that this number will surpass 10 million every year by 2051.  Stanford University scientists developed machine learning models that predict antibiotic susceptibility...
To estimate cell-to-cell heterogeneity in non-Markovian signaling systems, mathematicians from The Korea Advanced Institute of Science and Technology (KAIST) and Institute for Basic Science (IBS), Korea, devised a Bayesian inference approach. The approach could aid in the development of...
A project coordinated by a group of researchers from the Eichman lab and the Evolutionary Studies Initiative on the research of chemical compounds produced by bacteria was just published in mBio. The group was particularly interested in a class of...
Researchers from McGill University collaborated with the Canadian Light Source (CLS) at the University of Saskatchewan to unlock the full potential of small biological machinery that can significantly influence human health. Nonribosomal peptide synthetases (NRPSs), referred to as machines, are...
A team led by Karolinska Institutet used artificial intelligence (AI) and structural biology to learn more about two related proteins that protect the urinary tract and the gastrointestinal system from bacterial infection. The findings were published in "Nature Structural...

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Scientists Develop Hybrid Molecules by Drug Repurposing in an Effort to Design New Drugs...

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Controlling the spread of the highly contagious disease and protecting human health requires developing new medications that stay effective against growing COVID-19 variations. After spending...
Blood Biomarker that can Predict Onset of Crohn’s Disease

Researchers Identify Blood Biomarker that can Predict Onset of Crohn’s Disease Years Before Diagnosis

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A team led by the University of Toronto researcher discovered that a blood antibody can predict severe Crohn's disease up to seven years before...

Scientists Develop a Mathematical Model to Predict the Efficiency of Phage Therapy Against Pathogenic...

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Scientists from Inserm, Université Sorbonne Paris Nord, and Université Paris-Cité at the IAME Laboratory, with their collaborators at Institut Pasteur and the Paris Public...
Technological Advances in Drug Discovery

Recent Technological Advances in Drug Discovery

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The advent of technological advances such as artificial intelligence, machine learning, automation, robotics, etc., has accelerated the pace of drug discovery as well as...
Monkeypox Virus Genome Sequence

First Draft of Monkeypox Virus Genome Sequenced from Current Outbreak Patient

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In a quest to understand why the monkeypox virus, which is a less lethal relative of smallpox, has infected so many people around the...
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