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MHub.ai: Standardizing AI for Reproducible Medical Imaging

Saniya Sayyed - 0
An inter-institutional collaboration across the US, Germany, and the Netherlands introduces MHub.ai, an accessibility and reproducibility-prioritizing, open source platform for standardized access to AI...
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AI

ConGLUDe: Toward General-Purpose Foundation Models for Drug Discovery

Jainab Shaikh - 0
Researchers from Johannes Kepler University Linz, Austria, and Merck HealthCare, Germany, developed ConGLUDe (Contrastive Geometric Learning for Unified Computational Drug Design), an AI-based model for drug...
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AI

Claude Opus 4.5 and the Future of AI-Driven Research in Healthcare and Biotechnology

Jainab Shaikh - 0
The growing complexity of biomedical research and healthcare demands AI systems that can go beyond general assistance to support end-to-end scientific workflows. Building on...
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AI

DrugCLIP Enables High-Throughput Virtual Screening Across the Human Proteome

Saniya Sayyed - 0
Researchers at Tsinghua University have introduced DrugCLIP, a contrastive learning framework that enables ultrafast and accurate virtual screening at a genome-wide scale. Published in...
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Bioinformatics

Beyond the Sequence: How FoldMason is Redefining Multiple Protein Structure Alignment at Scale

Saniya Sayyed - 0
The authors at Seoul National University developed FoldMason, a free, open-source, progressive Multiple Structural Alignment (MSTA) method published in Science that uses a structural...
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Bioinformatics

De Novo Peptide Binder Generation: How moPPIt Targets ‘Undruggable’ Proteins

Saniya Sayyed - 0
Authors from the University of Pennsylvania and others innovated the motif-specific PPI targeting algorithm (moPPIt), a computational framework that integrates BindEvaluator along with Multi-Objective...
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AI

Generating DNA Sequences Using AI: DNA-Diffusion Promises Effective Gene Therapy

Saniya Sayyed - 0
The researchers at Broad Institute and Mass General Brigham in Nature Genetics propose DNA-Diffusion, the first ever generative diffusion framework trained on DNA accessibility...
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AI

Stanford’s SleepFM AI Reads Disease Risk from a Single Night of Sleep

Anchal Negi - 0
Stanford Medicine and researchers in Denmark and Boston have built an AI foundation model, SleepFM, that can read a single night of lab‑recorded sleep...
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AI

Google’s MedGemma 1.5 and MedASR: Transforming Medical Imaging and Speech Recognition with AI

Saniya Sayyed - 0
Google’s Health AI-Developed Foundations (HAI-DEF) has released an updated version of MedGemma (v1.5), an open-source generative AI model with enhanced capabilities in medical imaging...
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Bioinformatics

PanMAN Enables Scalable High-Resolution Pangenome Analysis

Saniya Sayyed - 0
The study led by researchers from UC San Diego and UC Santa Cruz introduces PanMAN, a new data structure designed to overcome the limitations...
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AI

Solving a Long-Standing Genomics Bottleneck: KAIST Proposes AI-Powered Strategy for Gene Function Prediction

Saniya Sayyed - 0
KAIST and UCSD researchers proposed AI-driven strategies for microbial gene function discovery, addressing the long-standing bottleneck where many microbial genes remain uncharacterized despite advances...
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AI-Powered Metagenomics: How MetagenBERT Predicts Disease From Raw DNA Sequences

Jainab Shaikh - 0
Researchers from Sorbonne University and Dauphine University, France, introduced MetagenBERT, a Transformer-based framework for disease prediction directly from raw metagenomic DNA without relying on...
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AI

ToposBio Unveils Topos-1: An All-Atom Foundation Model for Intrinsically Disordered Proteins

Saniya Sayyed - 0
Intrinsically disordered proteins (IDPs) are proteins that are central to neurodegenerative diseases and aggressive cancers like prostate cancer, have been considered ‘undruggable’ as structures...
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AI

CleaveNet Enables Scalable and Targeted Protease Substrate Design for Diagnostics and Therapeutics

Saniya Sayyed - 0
Scientists from MIT and Microsoft Research present CleaveNet, an AI-based pipeline that merges predictive and generative modeling for end-to-end peptide (short protein) design. By...
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AI

Advancing Peptide Therapeutics with PeptiVerse’s Unified Prediction Framework

Jainab Shaikh - 0
Researchers at the University of Pennsylvania developed PeptiVerse, a single platform that predicts drug-related properties of therapeutic peptides using either amino acid sequences or...
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Bioinformatics

Human Genome in 4D: Mapping Structure, Function, and Dynamics

Anchal Negi - 0
An integrated atlas of the human 4D genome just dropped, and it is breathtaking in its ambition. In a massive consortium effort, researchers from...
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AI

Redefining SBDD: PackDock Speeds Up Accurate Protein-Ligand Docking with Diffusion Models

Saniya Sayyed - 0
Researchers from the University of Shanghai, China, created PackDock, a diffusion-based side-chain packing model that predicts diverse side-chain conformations in protein binding pockets, both...
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AI

Beyond Tertiary Structures: SMRTnet’s Novel Approach to RNA Drug Discovery

Jainab Shaikh - 0
Researchers from Tsinghua University and Peking University in China developed the SMRTnet tool, which employs a deep-learning approach to identify interactions between small molecules...
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Bioinformatics

CoLabPCR: A One-stop Tool for Precise and Reproducible Primer Design

Jainab Shaikh - 0
Researchers at IBBM (Instituto de Biotecnología y Biología Molecular) and NOVABIOMA Biomanufacturing FlexCo introduced ColabPCR, a Google Colab-based Python notebook created along with collaborators...
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AI

From Variant to Disease: How V2P Improves Phenotype-Aware Pathogenicity Prediction

Saniya Sayyed - 0
Researchers at Mount Sinai Institute introduced Variant-to-Phenotype (V2P), a new machine learning framework that not only predicts whether a genetic variant is harmful but...
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VibeGen

MIT Researchers Develop VibeGen: An AI Tool that Designs Novel Proteins by Modeling their...

Saniya Sayyed - 0
Researchers at Mellon University and MIT introduce VibeGen, a generative AI framework for end-to-end de novo protein design conditioned on dynamics. The model generates...
Overview of CLASSIC

Scientists Introduce ‘CLASSIC’ Platform Enabling AI-Driven Genetic Circuit Design

Jainab Shaikh - 0
Researchers from Rice and Boston universities developed CLASSIC, a platform that combines long- and short-read sequencing to measure over 100,000 multi-gene circuits in human...
IntelliFold-2: An Open Source Alternative to AlphaFold 3 With Better Accuracy and Robustness

IntelliFold-2: An Open Source Alternative to AlphaFold 3 With Better Accuracy and Robustness

Saniya Sayyed - 0
The innovators behind intelliFold-2 at IntelliGen AI emphasize that IntelliFold-2 is designed as a state-of-the-art open source alternative to AlphaFold3 with stronger performance in...
GPCRact

How AI Predicts Whether a Drug Actually Works—Not Just Fits

Anchal Negi - 0
There is a question that has quietly haunted drug discovery for decades, one that sounds almost too basic to be a problem. A molecule...
RFdiffusion3.

Transforming All-Atom De Novo Design of Protein Using RFdiffusion3

Saniya Sayyed - 0
A major collaboration led by David Baker’s group at the Institute for Protein Design (UW) introduced RFdiffusion3 (RFD3), a next-generation version of the originally...