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BindCraft: Redefining Protein Binder Design with AI and One-Shot Precision

All important biological processes revolve around protein-protein interactions (PPIs'). Designing PPIs' is difficult, nonetheless, because of the intricate structural characteristics that define them. Researchers...

ProteusAI: Making Protein Design and Engineering Accessible to All

Protein structure prediction is a pretty big challenge in the field of bioinformatics as it depends on a multitude of factors. Imagine trying to...

Malaria Research Milestone: Scientists Design New Drug to Fight Drug-Resistant Malaria

Researchers from Yale University and other institutions have identified MED6-189 as a new antimalarial drug, a new development that might change the dynamics of...

The Future of Protein Engineering: Exploring the Potential of CodonMPNN

Making synthetic protein sequences from protein structures is a powerful use of protein engineering technology. It can be challenging to create designed proteins, though,...

MedChem Game: Gamifying Drug Discovery with AI on Your Android

Improved computational tools and artificial intelligence significantly improve drug discovery. This process has automated activities like molecular docking and predictive modeling to discover candidates...

Expansion in situ Genome Sequencing: A New Tool for Studying Nuclear Abnormalities

The investigation of nuclear anomalies and how they influence the regulation of genes warrants analysis of various cellular functions and diseases. The researchers from...

How ChemNet is Revolutionizing Protein-Small Molecule Conformational Modeling

Modeling of protein-small molecule systems offers advantages in speed and generality for exploring interactions with small molecules in the folded state; the modeling of...

Top 5 Laptops for Bioinformatics

Bioinformatics is a rapidly growing field that blends biology, computer science, and data analysis to make sense of biological data. This field is growing...

Breaking New Ground in Protein Function Prediction with Protein-Mamba

Determining the function of proteins is one defining aspect of molecular biology that also carries great potential in drug discovery and development. A better...

The Future of Cell Modeling: Building Virtual Cells with Artificial Intelligence

One of the most important concepts in biology is the cell, which is perhaps the smallest unit of life. This understanding and identifying the...

Unleashing the Power of Dynamics: A 4D Diffusion Approach to Protein Structure Prediction

The ability to anticipate the structure of proteins is essential for improving biological research, developing new pharmaceuticals, and designing experiments. It also helps to...

Everlasting Memory: Storing the Human Genome on a 5D Crystal

In a remarkable corridor of achievement, the scientists of the University of Southampton have reputedly gotten the ability to conserve the complete human genomic...

Unveiling Druggable Pockets with PocketVec: A Comprehensive Approach with Binding Site Descriptors

Target-based drug development depends heavily on characterizing druggable pockets, which are protein areas with the capacity to bind organic small molecules. Nevertheless, the process...

WikiPathways 2024: A Next-Generation Pathway Database

WikiPathways is an open-access biological pathway database that was first launched in 2007.  It is still being developed and updated by a group of...

Speed and Precision in Medical Imaging: The Promise of ScribblePrompt

Clinical care as well as scientific research depend heavily on biomedical image segmentation. Certain biomedical picture segmentation tasks can be accurately automated by deep...

Personalizing Pangenomes: A New Approach to Reduce Reference Bias

In a groundbreaking study published in Nature Methods, a group of scientists consisting of the UC Santa Cruz Genomics Institute, University of Ferrara, Google...

ProteinBench: Unveiling the True Potential of Protein Foundation Models

A notable progress in protein prediction and generative tasks, such as 3D structure prediction, protein design, and conformational dynamics, has been made in recent...

How Are Transformer Models Bridging the Gap Between Data and Drug Discovery?

A recently published work by researchers from the Wuhan Textile University, China, and Michigan State University, USA, has addressed the use of transformer models...

Unlocking Molecular Dynamics: Dynaformer, a Graph-Based Deep Learning Model for Binding Affinity Prediction

One major obstacle in structure-based drug design is accurately predicting the affinities of protein-ligand interaction. The accuracy of data-driven affinity prediction methods has improved...

Can We Measure Protein Interactions at Unprecedented Scale? MP3-seq Says Yes!

Numerous biological processes are regulated by protein-protein interactions (PPIs), and modified PPIs have uses in gene and cell therapy. Here, researchers from the University...

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Understanding FlexLMM: A Nextflow Framework for Genome-Wide Association Studies

Understanding FlexLMM: A Nextflow Framework for Genome-Wide Association Studies

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Genome-wide association Studies (GWAS) consider sequencing the DNA of a person and then comparing it with a population to find genetic markers associated with...
Meet metagWGS: A Flexible Workflow for Comprehensive Metagenomic Data Processing

Meet metagWGS: A Flexible Workflow for Comprehensive Metagenomic Data Processing

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An increasing number of studies employ metagenomic analyses to investigate the taxonomy and function of microorganism communities. In many microbial research, one typical job...
Cleveland Clinic and IBM Leverage AI to Revolutionize Drug Discovery for Pain Management

Cleveland Clinic and IBM Leverage AI to Revolutionize Drug Discovery for Pain Management

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In drug development, it isn't easy to learn molecular representation from chemical structures since traditional molecular representation techniques, such as sequence-based and graph-based approaches,...
The Protein Revolution: 2024 Nobel Prize in Chemistry Pioneers Protein Design and AI-Powered Predictions

The Protein Revolution: 2024 Nobel Prize in Chemistry Pioneers Protein Design and AI-Powered Predictions

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In a groundbreaking announcement that has sent ripples through the scientific community, the Royal Swedish Academy of Sciences has awarded the 2024 Nobel Prize...
PlasmidGPT: Transforming Plasmid Design with Generative AI

PlasmidGPT: Transforming Plasmid Design with Generative AI

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Recent research shows that within the domain of synthetic biology, there have been tremendous improvements, especially in designing and engineering biological systems. Plasmids, crucial...