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Google’s DeepMind Unveils AlphaMissense: A Breakthrough AI Tool for Decoding Genetic Enigmas

Google's DeepMind scientists have made a monumental stride with the inception of AlphaMissense, an AI tool that can pinpoint genes responsible for diseases. This...

Machine Learning and Phylogenetic Analysis Join Forces to Predict Antibiotic Resistance in Pathogenic Bacteria

Tuberculosis has been known to be a significant threat for many years now. Despite the development of a number of preventative strategies and medications,...

Meet DRfold: A Novel Method to Predict RNA Tertiary Structures with Unprecedented Accuracy

RNAs are essential components of physiological activities, however, accurately modeling their structures has long posed a challenge due to their complex structures. The National...

Meet AutoBA: A New Tool Making Bioinformatics Analysis Easy

Recent advancements in technology have now made it feasible for scientific researchers to be able to collect large amounts of biological data using a...

CodonBERT: A New Large Language Model Could Help Design Optimized mRNA Vaccines and Therapeutics

A team of researchers at Digital R&D, Sanofi, USA, developed CodonBERT, a transformer-based large language model that is used for performing tasks related to...

Large Language Models Meet Single Cell Transcriptomics: Unlocking Biological Insights with Cell2Sentence

Large language models, such as GPT (Generative Pre-trained Transformer), have showcased remarkable proficiency in various natural language processing tasks. Their ability to understand and...

Machine Learning Predicts Mood in Chronic Stroke Patients and Identifies the Link Between Stroke and Depression

Stanford's scientists used Machine Learning to elucidate the relationship between stroke and depression by identifying a biomarker in stroke survivors. The findings may provide...

Virtual Drug Screening with Less Data: Boosting Predictions with Transfer Learning and Kernel Methods

A team of researchers at the Eric and Wendy Schmidt Centre at the Broad Institute of MIT and Harvard developed a model that uses...

3Dmapper: A New Tool for Mapping Genetic Variants to Protein Structures at BioBank Scale

Centuries after the first proteins were identified and characterized, their complexity proves a challenge for scientists all over the world. Their creation, evolution, and...

PeptideBERT: A Transformer-based Language Model for Predicting Peptide Properties using Amino Acid Sequences

Scientists at Carnegie Mellon University, USA, introduced PeptideBERT, a language model that is capable of predicting the properties of proteins and peptides solely based...

Deep Learning Powers New Methods for Protein Remote Homology Detection and Structural Alignment

Comprehending sequence–structure–function relationships is challenging for proteins with low similarity to existing proteins. New and improved alignment approaches are required for such proteins to...

Meet BARNACLE: A New Tool to Predict RNA Contacts using Data Efficient Deep Learning

In the pursuit of understanding how RNA structure and function are related, predicting RNA structures becomes a tool alongside experimental approaches. However, the limited...

Meet HighFold: An AlphaFold-based Algorithm to Predict Cyclic Peptide Monomers and Complexes with Precision

Cyclic peptides represent an emerging class of drugs that combine the advantageous attributes of small molecules with those of antibodies or protein-based therapeutics. Scientists...

Meet XVir: A Promising Transformer-based Approach to Spot Viral Reads in Human Cancer Samples

A team of researchers at The University of Texas at Austin developed a novel algorithm, XVir, that combines deep learning methods and transformers to...

Large Language Models Offering Solutions to Tackle Biological Complexity

Large Language Models (LLMs) have emerged as dynamic tools with the ability to transform the landscape of biological research in a world driven by...

Meet Flow: An Ultimate Bioinformatics Data Analysis and Management Solution

Scientists at King's College London, UK, and collaborators have introduced 'Flow,' an open-access web platform to perform bioinformatics analysis. Flow provides the capability to...

ChatGPT Empowers Clinical Decision Making with Impressive Accuracy

The large-language model (LLM)-based model, ChatGPT, had its clinical decision-making abilities put to the test in a joint study by researchers from Harvard Medical...

Revolutionizing Parkinson’s Care: Harnessing Artificial Intelligence to Detect Disease Severity at Home

A team of researchers has recently developed an Artificial Intelligence (AI) based model for detecting the severity of the disease's progression and its symptoms...

Oxford Researchers Develop a Machine Learning Model to Predict 10-Year Breast Cancer Mortality Risk

A group of researchers affiliated with Oxford University, UK, have developed a prognostic model backed by the most extensive information set spanning a national,...

Meet FateMap: A Barcoding Approach to Decode Why Certain Cells Resist Anti-Cancer Therapies

A collaborative research effort led by scientists and engineers at the University of Pennsylvania and Northwestern University led to the development of FateMap, a...

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MitoSpace creates the first atlas of drug-induced mitochondrial phenotypes.

MitoSpace: A Novel Mitochondrial Phenotypic Atlas for Drug Discovery and Diagnostics

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A collaborative effort between the Departments of Pharmacology, Chemistry, and Biochemistry at the University of California, San Diego, led to the development of MitoSpace,...
Streamlining Differential Expression Analysis on Bulk RNA-seq Data with PyDESeq2

Streamlining Differential Expression Analysis on Bulk RNA-seq Data with PyDESeq2

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Exploring bulk RNA-seq data has become a cornerstone for uncovering crucial insights into gene expression patterns and their relationship to phenotypes in biomedical research....
Achieving RNA's AlphaFold Moment: How Close Are We?

Achieving RNA’s AlphaFold Moment: How Close Are We?

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AlphaFold's breakthrough in solving the protein structure prediction problem has ignited enthusiasm to apply similar methods to predict the 3D structures of RNAs. However,...
Accurate Annotations of Eukaryotic Genomes using RNA-Seq Data Made Easy: The BRAKER3 Advantage

Accurate Annotation of Eukaryotic Genomes Made Easy: The BRAKER3 Advantage

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Researchers from the University of Greifswald, Germany, introduced a new version of the BRAKER software BRAKER3, notably improving the annotation of eukaryotic genomes. Its...
DrugChat: A ChatGPT-like System for Drug Compound Discovery

DrugChat: A ChatGPT-like System for Drug Compound Discovery

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A team of researchers at the University of California, San Diego, came together to develop a chatbot specifically catered to drug discovery called DrugChat....