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Revolutionizing Molecular Dynamics Analysis with VIAMD: A Unified Approach to Visualization, Property Calculation, and Synergistic Analysis

Many different tools are needed for the standard molecular dynamics (MD) analysis workflow, which frequently leads to a lack of coordination and interaction between...

From Genes to Therapies: How Bioinformatics is Revolutionizing Translational Medicine

We live in an era of big data. Advancements in high-throughput sequencing and other omics technologies have led to exponential growth in biological data...

BARtab and Bartools: Revolutionizing Cellular Barcoding Analysis in Genomics Research

Researchers from the Peter MacCallum Cancer Centre, Australia, have introduced an integrated open-source toolset called BARtab and bartools to streamline the analysis of cellular barcoding experiments....

Decoding the Dance of Proteins and Nucleic Acids: Machine Learning Empowers Protein-Nucleic Acid Complexes Prediction with RoseTTAFoldNA

Researchers at the University of Washington, USA, have developed a new AI system called RoseTTAFoldNA that can rapidly and accurately predict the 3D structures...

UK Biobank Releases Unprecedented Genomic Data Trove to Transform Global Health

In a monumental milestone, UK Biobank has unveiled open access to incredible whole genome sequencing data for its over half a million participants. This...

Transforming Fragment-based Drug Design: Stanford’s FRAME Employs Machine Learning to Expand Fragments into Ideal Ligands

Stanford University researchers developed FRAME (Fragment-Based Molecular Expansion), a machine learning framework that uses three-dimensional structures of interactions between proteins and ligands to facilitate...

Decoding the Protein-Ligand Enigma: A Deep Dive into Deep Learning Approaches for Binding Affinity Prediction

Researchers from the University of Edinburgh, UK, explore the impact of ligand and protein encodings on binding affinities prediction for different data sets, a...

Genome LLMs: Revolutionizing Genomics with Transformer-based Large Language Models

Deep learning techniques have had a significant influence on genomics and the sequencing techniques employed in the field due to the exponential advancements in...

The Tail that Wiggles: A Reaction-Diffusion Model Unveils the Mechanism Behind Sperm Tail Movement

The graceful, rhythmic beating of slender cellular appendages called flagella allows sperm cells and microorganisms like algae to swim. But how these waving motions...

Transforming Infection Diagnosis: Saliva-Based mRNA Biomarker for Accurate Detection

Since the COVID pandemic began, the world has been reminded of the poor reliability of elevated body temperature for detecting infections. Even when infected...

Meet NeuroVelo: A New Tool to Decode Cellular Dynamics from Single-cell Transcriptomic Data

A study conducted at the International School for Advanced Studies (SISSA) in Trieste, Italy, introduced NeuroVelo, a novel method tackling the challenge of reconstructing...

New Machine Learning Technique Predicts Cancer Patient Cure Rates More Accurately

As computing power has exponentially grown, machine learning (ML) techniques have gained immense popularity in healthcare - including predicting outcomes for patients with devastating...

UK Approves Revolutionary World-first Gene Editing Treatment for Blood Disorders

The UK has achieved a historic milestone by becoming the first country to authorize a revolutionary new treatment for two serious inherited blood conditions...

UCSD’s EUGENe: A New Deep Learning Toolkit to Decode the Regulatory Genome

Researchers at the University of California, San Diego, built EUGENe (elucidating the utility of genomic elements with neural nets) – an end-to-end Python toolkit...

Enlightening the Proteomic Space with Chroma: A Revolutionary Generative Model for Protein Design

Proteins are incredible molecules that carry out nearly every function necessary for life. However, their staggering complexity has made designing new proteins an immensely...

Unravel Cell-cell Communication with CellPhoneDB v5: A Cutting-edge Single-cell Multiomics Toolkit

We often underestimate the crucial role played by communications between cells to sustain living organisms. Flawless communication between cells is a necessity to maintain...

Unlocking the Secrets of Disease: The Imageable Genome and the Future of Molecular Medicine

Researchers at the University of Lucerne utilized molecular imaging to evaluate the expression of certain regions of the human genome. The imaging techniques are...

Demystifying Big Data with TBtools-II: A Versatile and Customisable All-in-One Platform for Bioinformatics Analysis

TBtools, a toolkit used for data analysis and bioinformatics tasks, was released in 2020 and quickly found a large audience – thousands of researchers...

Meet MiRGraph: A Novel Deep Learning Algorithm to Predict miRNA-target Interactions

A team of researchers from McGill University and Hunan University developed MiRGraph, a multi-view feature-learning method based on transformers that have the ability to...

Navigating the Complex Transcriptomic Landscape of Neurodegeneration with ZEBRA

Neurodegenerative diseases like Alzheimer's and Parkinson's remain poorly understood despite intensive research. While sequencing studies have profiled diverse brain cell populations, integrating findings into...

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Analyzing Bio-Ontologies Made Easy: A Deep Dive into simona R Package for Semantic Similarity

Analyzing Bio-Ontologies Made Easy: A Deep Dive into simona R Package for Semantic Similarity

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As modern biology embraces high-throughput genomics and multi-omics profiling, the torrents of data now routinely generated necessitate improved systems organizing information to enable meaningful...
Unleashing the Power of Recurrent Neural Networks for Orally Bioavailable Drug Design with Novomol

Unleashing the Power of Recurrent Neural Networks for Orally Bioavailable Drug Design with NovoMol

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NovoMol is a novel de novo technique that increases the efficiency of clinical trial times by mass-generating therapeutic molecules with excellent oral bioavailability through...
Meet Multiple Protein Profiler: A New Tool for Analyzing Proteomic Datasets

Meet Multiple Protein Profiler: A New Tool for Analyzing Proteomic Datasets

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Dalhousie University, Canada researchers have developed a new web-based tool called Multiple Protein Profiler (MPP) that can efficiently calculate 12 key physicochemical properties of...
French Startup Selling $1,000 DNA Storage Cards Capable of Storing Messages in Genetic Code

French Startup Selling $1,000 DNA Cards Capable of Storing Messages in Genetic Code

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Biomemory, a French digital storage startup, recently unveiled encapsulated DNA storage devices the size of credit cards, holding personalized messages as brief proofs of...
Universal Cell Embeddings - A Revolutionary Foundation Model for Cell Biology

Unlocking the Secrets of Life: Universal Cell Embeddings – A Revolutionary Foundation Model for...

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Universal Cell Embedding (UCE) is a foundation model proposed by a group of scientists from Stanford University. Using a corpus of cell atlas data...