Small molecule drug discovery could be revolutionized by molecular docking tools. Still, current molecular docking methods are slow to screen targets, leading to missed...
To fight cancer, we must stop their metastasis or uncontrolled multiplication. Hence, it is important to understand what proteins these cancer cells need for...
Information about the function and three-dimensional structures of proteins can be found in the AlphaFold Protein Structure Database (AFDB). Almost all of the proteins...
In this day and age, artificial intelligence is everywhere; it’s omnipresent. It is utilized in healthcare, finance, entertainment, IoT, agriculture, marketing, cybersecurity, and so...
Scientists can now model interactions and assess the possibility that proteins will form multimers or interact with other proteins or nucleic acids thanks to...
Cancer, a complex disease arising from genetic alterations, has been a major global health challenge. Researchers have been able to make considerable progress in...
Scientists present a modular bond-centric strategy for designing protein nanomaterials that are motivated by the wide range of chemical configurations that may be produced...
The challenge of connecting a protein sequence to its fundamental biological function is becoming more and more significant in the field of biology. The...
DeltaDock is a novel two-stage framework capable of performing molecular docking, which has not been achieved before. It does so by combining the strengths...
Deep learning models have been used to predict the pathogenicity of mutations in hereditary breast cancer gene variants in the UK Biobank. Here, researchers...
In the field of biological research, understanding the relationship between different biological components and their function is complicated. Functional analysis, a part of computational...
Drug discovery, synthetic biology, and enzyme engineering are all dependent on the ability to comprehend and create biomolecules, such as proteins and tiny molecules....
A recent study by a team of researchers has made significant strides in unraveling this complex puzzle of human interaction. The human interactome encompasses...
Genome-wide association Studies (GWAS) consider sequencing the DNA of a person and then comparing it with a population to find genetic markers associated with...
An increasing number of studies employ metagenomic analyses to investigate the taxonomy and function of microorganism communities. In many microbial research, one typical job...
In drug development, it isn't easy to learn molecular representation from chemical structures since traditional molecular representation techniques, such as sequence-based and graph-based approaches,...
In a groundbreaking announcement that has sent ripples through the scientific community, the Royal Swedish Academy of Sciences has awarded the 2024 Nobel Prize...
Recent research shows that within the domain of synthetic biology, there have been tremendous improvements, especially in designing and engineering biological systems. Plasmids, crucial...
All important biological processes revolve around protein-protein interactions (PPIs'). Designing PPIs' is difficult, nonetheless, because of the intricate structural characteristics that define them. Researchers...
In a significant move for the scientific community, Google DeepMind has finally released the open-source code for AlphaFold3, their groundbreaking protein structure prediction tool....
As biologists have noticed, evolution has modified both bacteria and bacteriophages (i.e., viruses of bacteria), making them more complex on a smile's molecular level....
Virtual screening techniques, which concentrate on binding affinities, are becoming more and more popular for early-stage drug development. Although deep learning-based methods predict binding...
The process of drug discovery has always necessitated a large amount of time and effort as it requires a careful combination of both chemical...
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