Saturday, May 25, 2024
HomeDatabase

Database

Popular

Trending

Atom-scale Precision: ESM-AA’s Multi-scale Approach to Unified Molecular Modeling

The subject of protein engineering has shown great promise for protein language models. Unfortunately, the main size at which the existing protein language models...

Exploring the World of Transcriptomics: Techniques, Algorithms, and Tools

Transcriptomics has emerged as a powerful tool in modern biology; it deals with the study of the entire set of RNA transcripts produced by the genome at...

Towards Standardization and Scalability: How Nextflow and nf-core are Empowering Bioinformatics Communities

FAIR bioinformatics research relies heavily on standardized analysis pipelines. Point-and-click pipeline programs like Galaxy have gradually given way to command-line programs like Nextflow and...

Revolutionizing Antibody Structure-based Design with AntiFold: A Breakthrough in Inverse Folding Technology

Scientists from the University of Oxford along with the Technical University of Denmark have introduced AntiFold: a specialized model for antibody design that will...

Revolutionizing Biotechnology with Predictive Tools: A New Era of Discovery

For years, biocatalysis has depended on bioprospecting – in essence, sieving through Nature's enzyme riches to find the best match. However, this method, though...

Unlocking New Possibilities in Drug Design: DrugLLM’s Novel Approach to Few-Shot Molecule Generation Using Open Large Language Models

The languages of biology and chemistry are difficult for language processing and computer vision systems to grasp, notwithstanding their advances in language processing. Although...

Unleashing the Power of Foundation Models for Cancer Imaging Biomarker Discovery

Despite the immense hurdles posed by cancer, technological developments, particularly in medical imaging and biomarker identification, provide a ray of hope. Foundation models have...

Unveiling the Future of Transcriptomics: CELLama – A Foundation Model Revolutionizing Single Cell and Spatial Analysis

Comprehensive data atlases have been made possible by the data-driven nature of biomedical research thanks to large-scale single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics...

Faster, More Accurate Spatial Omics: How BANKSY Streamlines Data Analysis

Spatial omics involve scientists generating maps of gene expression within tissues as they continue to evolve. This is an extremely important development with significant...

Turning the Tide Against Antibiotic Resistance: Protein-BERT’s Accurate and Interpretable Predictions

Scientists from Waseda University and Hitachi, Ltd., Japan, developed a novel approach for predicting antibiotic resistance genes (ARGs) resistance mechanisms using Protein-BERT, a protein...

Unraveling the Mysteries of Molecular Dynamics: MDverse Sheds Light on Dark Matter

Molecular dynamics (MD) files have accumulated in generalist data repositories due to the rise of open science and the lack of a worldwide repository...

The Ultimate Molecular Explorer: AlphaFold 3, DeepMind’s AI Marvel to Unravel the Mysteries of All Life’s Molecules

DeepMind and Isomorphic Labs unveil AlphaFold 3, an AI model that predicts structures and interactions of all biomolecules like proteins, nucleic acids, ligands, and...

Designing Multi-Tasking Drugs: How POLYGON Makes Polypharmacology Easier with Deep Generative Chemistry

Drugs with polypharmacology, or substances that block several proteins, offer a wide range of uses but are challenging to create. To overcome this difficulty,...

Did Aquatic Algae Pave the Way for Lush Forests? New Research Suggests Yes!

Have you ever wondered how those dense jungles and tall trees appear? It began with a leap from the water, a colonization attempt by...

Deciphering the Future with Decipher: A Computational Pipeline for Single-cell Profile-based Context-specific Mechanistic Insights

The development of single-cell profiling methods has transformed our understanding of the cellular and molecular processes underlying disease states and how they respond to...

A New Era of AI in Medicine: Google’s Med-Gemini Sets New Standards

AI faces significant obstacles in achieving excellence in a wide range of medical applications since it needs sophisticated reasoning, access to current medical information,...

Unveiling ChatNT: The Conversational AI Revolutionizing How We Explore DNA, RNA & Proteins

InstaDeep and BioNTech scientists introduced ChatNT, a multimodal conversational agent that has an advanced understanding of biological sequences like DNA, RNA, and proteins. ChatNT...

REvoLd: Accelerating Drug Discovery Through Evolutionary Algorithm-Driven Ultra-Large Library Screening in Rosetta

An endeavor to create new medicinal compounds that can reach great heights, though challenging, remains vital. The advent of computer tools has led to...

Multi-omics Data Analysis Made Easy with ExpOmics: A Comprehensive Web Platform for Robust Analysis

Biological research has been in a golden age ever since the advent of high-throughput technologies. We can now probe deeper into living systems than...

DeepGene: Revolutionizing Genomics with Pan-genome Graph Transformer-based Foundation Model

A significant issue in genome research is the Nucleotide Transformer, which makes DNA sequence interpretation accurate only with models such as DNABERT-2. Although these...

Learn Bioinformatics

Must Read

Can We Truly Understand Proteins Through Text? ProtT3 Says Yes!

Can We Truly Understand Proteins Through Text? ProtT3 Says Yes!

0
The discovery of ProtT3 marks a significant recent advance in the fast-developing science of bioinformatics. ProtT3, developed by researchers at the National University of...
Decoding VEXAS Syndrome: How Single-Cell Genotype-Phenotype Mapping Identifies New Treatment Avenues

Decoding VEXAS Syndrome: How Single-Cell Genotype-Phenotype Mapping Identifies New Treatment Avenues

0
Clonal variation emerges across tissues as a result of somatic evolution, with far-reaching consequences for human health. The VEXAS (Vacuoles E1 enzyme X-linked Autoinflammatory...
StarFunc: Revolutionizing Protein Function Prediction Leveraging Template-based and Deep Learning Approaches

StarFunc: Revolutionizing Protein Function Prediction Leveraging Template-based and Deep Learning Approaches

0
A recent study by the Chengxin Zhang lab from the University of Michigan introduced StarFunc, an accurate protein function prediction approach integrating cutting-edge deep...
Decoding Protein Function with ProteinCLIP: How Natural Language Enhances Protein Language Models

Decoding Protein Function with ProteinCLIP: How Natural Language Enhances Protein Language Models

0
Language models have made a new era of biological sequence modeling possible. However, it is still difficult to extract significant sequence-level embeddings from these...
SYNY: A Powerful Pipeline for Investigating and Visualizing Genome Collinearity

SYNY: A Powerful Pipeline for Investigating and Visualizing Genome Collinearity

0
Scientists have questioned the comparison of genes' organization across various species. Collinearity analysis is a helpful way to go about this task, although it...