Thursday, June 30, 2022

BIOINFORMATICS TOOLS

Phylogenetic Analysis

  • MEGA – Molecular Evolutionary Genetics Analysis package. It is a computer software for conducting automatic and manual sequence alignment and constructing phylogenetic trees.
  • Phylip – It is a free package of programs for inferring phylogenies.
  • PAML – A package of programs for phylogenetic analyses of DNA or protein sequences using maximum likelihood.
  • DAMBE – Software package for extensive Data Analysis in Molecular Biology and Evolution
  • iTOL – Interactive Tree Of Life is an online tool for the display, annotation and management of phylogenetic and other trees.

Must Read

Heart Failure

Single-Cell Map of Heart Failure Provides Insights into Novel Potential Therapeutic Targets and Biomarkers

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Researchers have discovered molecular fingerprints that lead to biological causes of disease by analyzing individual cardiac cells from heart failure patients. Heart failure is an...
single-cell RNA sequencing, TAS-Seq, RNA Sequencing

TAS-Seq – A New Sensitive, and Powerful Single-Cell RNA Sequencing Technique Surpasses Competition

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The emergence of single-cell RNA sequencing (scRNA-seq) has now made it possible to analyze the internal workings of hundreds of cells at once, revolutionizing...
picasso technique

PICASSO Technique Helps Scientists Visualize Biological Molecules into Technicolor​

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Scientists from the Korea Advanced Institute of Science and Technology propose the PICASSO technique, which enables more than 15-color imaging of spatially overlapping proteins...
Antibiotic Resistance

High-Resolution Cryo-EM Structure of Type IV Secretion System Offers New Hope for Fighting Antibiotic...

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A group of researchers from UCL and Birkbeck has discovered a novel strategy to help limit the spread of antibiotic resistance, which has the...
genome structure

Applying 3D Computational Simulation to Reveal the Secrets of the Genome Structure in the...

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A research team from Nagoya University in Japan has created a 3-Dimensional computational simulation of the formation of the genome structure in the human...