Thursday, June 30, 2022

BIOINFORMATICS TOOLS

Protein Structure Analysis Tools

Protein Structure Modeling

  • Swiss Model – Fully automated protein structure homology-modelling server.
  • Phyre2 – Protein Homology/analogY Recognition Engine V 2.0.
  • SwisDock – A web service to predict the molecular interactions that may occur between a target protein and a small molecule.
  • AutoDock – AutoDock is a suite of automated docking tools.
  • CASP – Protein structure prediction center.
  • Rosetta – The Rosetta software suite includes algorithms for computational modeling and analysis of protein structures. Further, it offers de novo protein design, enzyme design, ligand docking, and structure prediction of biological macromolecules and macromolecular complexes. 

Protein 3D Visualization

  • Chimera – a program for the interactive visualization and analysis of molecular structures and related data.
  • ChimeraX – It is the next-generation interactive molecular visualization program.
  • Swiss-PDB Viewer – Application for analyzing several proteins at the same time as well as protein modeling server.
  • PyMol – PyMOL is a molecular visualization system maintained and distributed by Schrödinger.
  • VMD – Molecular visualization program for displaying, animating, and analyzing large biomolecular systems using 3-D graphics and built-in scripting.
  • RasMol – Molecular visualization tool.

Must Read

Heart Failure

Single-Cell Map of Heart Failure Provides Insights into Novel Potential Therapeutic Targets and Biomarkers

0
Researchers have discovered molecular fingerprints that lead to biological causes of disease by analyzing individual cardiac cells from heart failure patients. Heart failure is an...
single-cell RNA sequencing, TAS-Seq, RNA Sequencing

TAS-Seq – A New Sensitive, and Powerful Single-Cell RNA Sequencing Technique Surpasses Competition

0
The emergence of single-cell RNA sequencing (scRNA-seq) has now made it possible to analyze the internal workings of hundreds of cells at once, revolutionizing...
picasso technique

PICASSO Technique Helps Scientists Visualize Biological Molecules into Technicolor​

0
Scientists from the Korea Advanced Institute of Science and Technology propose the PICASSO technique, which enables more than 15-color imaging of spatially overlapping proteins...
Antibiotic Resistance

High-Resolution Cryo-EM Structure of Type IV Secretion System Offers New Hope for Fighting Antibiotic...

0
A group of researchers from UCL and Birkbeck has discovered a novel strategy to help limit the spread of antibiotic resistance, which has the...
genome structure

Applying 3D Computational Simulation to Reveal the Secrets of the Genome Structure in the...

0
A research team from Nagoya University in Japan has created a 3-Dimensional computational simulation of the formation of the genome structure in the human...