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Bioinformatics

DRUG-seq: A Game-Changing Approach to Transcriptional Profiling in Drug Discovery

Dr. Tamanna Anwar - 0
The identification and comprehension of the mechanisms of potential drug compounds is a complex and expensive endeavor in the constantly changing pharmaceutical research landscape....
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AI

AI-Driven Macrocycle Design: How RFpeptides Generate High-Affinity Protein Binders for Diagnostics and Therapeutics

Deotima Chakraborty - 0
Large-scale screening techniques that are resource-intensive and offer limited control on binding mode are usually used to produce macrocyclic binders to therapeutic proteins. There...
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AI

Can InterPLM Decode the Hidden Language of Protein Modeling and Design AI?

Anchal Negi - 0
The emergence of Protein Language Models (PLMs) is changing biological research for the better through efficient prediction of functional annotations and protein structures. However,...
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AI

Learning from Extremophiles: HyperMPNN’s Revolutionary Approach to Thermostable Protein Design

Deotima Chakraborty - 0
Recombinant proteins must be stable in order to be used in biotechnological or medicinal applications. Both the creation of new proteins and the stabilization...
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AI

Unlocking the Power of Single-cell RNA Sequencing with scExplorer

Anchal Negi - 0
With its recent advancements, scRNA sequencing has enabled scientists to view the biological world at the most local of levels- the single cell. Thanks...
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Bioinformatics

Seamless Multi-Omics Integration Made Easy with iModMix

Deotima Chakraborty - 0
Integrating metabolomics with other omics and providing insights into the biology of disease requires bioinformatics competence. Integration is difficult with present approaches, though, as...
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AI

Unlocking Chemical Space: TamGen’s Generative AI Approach for Target-Aware Molecule Generation in Drug Discovery

Deotima Chakraborty - 0
Novel compounds can be discovered in the wide chemical space due to generative drug design that enables one to develop molecules that are effective...
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AI

Exploring New Frontiers in SARS-CoV-2 Research with The Virtual Lab

Anchal Negi - 0
When COVID-19 emerged as a global catastrophe, the scientists had only one goal: to come up with the possible treatments for the virus SARS-CoV-2,...
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AI

RhoFold+: Transforming RNA 3D Structure Prediction with Deep Learning

Deotima Chakraborty - 0
Although RNA 3D structures are important in understanding their functions and in the design of new drugs, their accurate prediction is still a challenge....
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AI

Unlocking the Secrets of RNA: How RNA-GPT is Transforming the Way We Explore and Understand RNA

Deotima Chakraborty - 0
RNAs are crucial molecules that convey genetic information necessary for life, and they have a big impact on biotechnology and medicine development. However, the...
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AI

From Concept to Reality: Efficient Protein Pocket Design with PocketGen

Anchal Negi - 0
Protein pockets have been an integral part of drug discovery for several years and are also targeted during the design of novel molecules. Pockets...
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AI

Evo: A Genomics Foundation Model Redefining Sequence Modeling and Design

Deotima Chakraborty - 0
The DNA sequences of all living organisms hold the fundamental instructions for life. Massive datasets of entire genomes, together with machine learning advancements, may...
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AI

Innovating Through Collaboration: The Protein Engineering Tournament’s Impact on Computational Design

Neermita Bhattacharya - 0
Protein engineering heavily relies on generating sequences using computational models. Limitations such as lack of benchmarking opportunities, scarcity of large protein function datasets, and...
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AI

How BALM is Redefining Binding Affinity Prediction for Unseen Targets and Drugs

Anchal Negi - 0
In the fast-paced world of drug discovery, one of the most crucial aspects is understanding protein-ligand interactions. With the correct algorithms for predicting protein-ligand...
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AI

EPBDxDNABERT-2: A Multi-Modal Deep Learning Model for Enhanced Transcription Factor DNA Binding Prediction

Deotima Chakraborty - 0
It has been demonstrated that there is a functional correlation between transcriptional activity, thermodynamic stability, DNA breathing, and transcription factor (TF) binds. The researchers...
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Biotech

Omega-3 and Omega-6 Fatty Acids: New Allies in Cancer Prevention

Dr. Tamanna Anwar - 0
A groundbreaking new research from the University of Georgia unveils that omega-3 and omega-6 fatty acids may play an integral role in cancer prevention,...
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AI

The Future of Bioinformatics: Building Expertise for Data-Driven Discovery

Dr. Tamanna Anwar - 0
In an era where biological data grows exponentially, bioinformatics has emerged as a vital interdisciplinary field that combines biology, computer science, mathematics, and statistics....
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AI

The Power of Foundation Models in Pathology: How Paige’s Virchow is Changing Cancer Detection

Neermita Bhattacharya - 0
Computational pathology is the evolution of cancer diagnosis into a new era, with the application of artificial intelligence to understand complex histopathology images. Generally,...
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Bioinformatics

Unlock Molecular Conformations with Moltiverse Using Enhanced Sampling Molecular Dynamics Simulations

Deotima Chakraborty - 0
For drug development to be effective, it is essential to accurately predict the various bound-state conformations of small compounds, especially in situations where intricate...
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AI

AlphaFold3 Goes Open Source: A New Chapter in AI-Powered Protein Science

Dr. Tamanna Anwar - 0
In a significant move for the scientific community, Google DeepMind has finally released the open-source code for AlphaFold3, their groundbreaking protein structure prediction tool....
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Must Read

Harnessing AI for Molecular Discovery: The Promise of Molecular Dynamics Language Models

Harnessing AI for Molecular Discovery: The Promise of Molecular Dynamics Language Models

Deotima Chakraborty - 0
Although molecular dynamics (MD) simulations provide accurate representations of the motion of molecular systems, molecular biology and materials science are challenged by the computational...
Decoding the Genetic Mechanism of B Chromosome Drive in Rye

Decoding the Genetic Mechanism of B Chromosome Drive in Rye

Anchal Negi - 0
The extra genetic material, which appears as 'B chromosomes,' has been a riddle for security for many species. They are of least concern for...
Streamlining High-Throughput Protein Complex Modeling with AlphaPulldown2

Streamlining High-Throughput Protein Complex Modeling with AlphaPulldown2

Deotima Chakraborty - 0
AlphaPulldown version 2.0, a noteworthy computational biology program that transforms protein structure modeling, is presented by researchers from the European Molecular Biology Laboratory, Hamburg,...
The G2PT Model: Bridging the Gap Between Genotype and Phenotype Using Hierarchical Transformers

The G2PT Model: Bridging the Gap Between Genotype and Phenotype Using Hierarchical Transformers

Anchal Negi - 0
Gaining insight into the peculiar relationship between the genes we possess and the characteristics they express is undoubtedly one of the most intriguing quests...
Evolutionary Scale's ESM Cambrian: Revolutionizing Protein Understanding at the Scale of Life with Unsupervised Learning

Evolutionary Scale’s ESM Cambrian: Revolutionizing Protein Understanding at the Scale of Life with Unsupervised...

Anchal Negi - 0
Proteins are the most essential molecules for all forms of life on Earth. They perform a vast number of actions vital for life. However,...

CBIRT provides short term training in bioinformatics for students/researchers/life science graduates, etc. The program aims at providing rigourous training required to excel in current dynamic scientific research environment. For more details

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