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Concept based articles provide a balance of information on recent bioinformatics trends.

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Population Specific Genome Graphs

Scientists from Seven Bridges Genomics Show how Utilizing Population-Specific Genome Graphs Enhances High-throughput Sequencing...

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Seven Bridges Genomics, USA, scientists demonstrate an approach for iteratively augmenting tailored genome graphs for targeted populations on whole-genome samples of African ancestry.  Due to...
Teixobactin–membrane-interaction

Teixobactin Kills Bacteria by Attacking the Cell Envelope in Two Ways

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The development of new mechanisms for antibiotics is essential to combating antimicrobial resistance. With its unique chemical scaffold, Teixobactin is a new class of...
Scientists Propose a Computational Approach for Predicting HIV Combination Therapy to Prevent Viral Escape and Rebound

Scientists Propose a Computational Approach for Predicting HIV Combination Therapies to Prevent Viral Escape...

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Scientists from the University of Washington, the Max Planck Institute for Dynamics and Self-Organization, and the University of Cologne carefully formulated combination therapies from...
Molecular Dynamics Simulations and Diversity Selection by Extended Continuous Similarity Indices

Scientists Recognize Extended Continuous Similarity Indices as a Novel Tool to Study the Conformational...

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Scientists from the University of Florida, US, and the Research Centre for Natural Science, Hungary, developed a new frame selection algorithm, "ECS-MeDiv," as an...
Long fibrils of teixobactin (yellow arrows) and lipid II (red-blue dots) lead to weak spots in the cell membrane of the bacterium.

Scientists Discover a Novel Two-step Mechanism the Antibiotic ‘Teixobactin’ uses to Kill Antibiotic-Resistant Bacteria

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The University of Utrecht scientists have uncovered a novel mechanism for how drugs eradicate antibiotic-resistant bacteria. Teixobactin, an antibiotic, kills bacteria by destroying their...