BIOINFORMATICS TOOLS
Protein Structure Analysis Tools
Protein Structure Modeling
- Swiss Model – Fully automated protein structure homology-modelling server.
- Phyre2 – Protein Homology/analogY Recognition Engine V 2.0.
- SwisDock – A web service to predict the molecular interactions that may occur between a target protein and a small molecule.
- AutoDock – AutoDock is a suite of automated docking tools.
- CASP – Protein structure prediction center.
- Rosetta – The Rosetta software suite includes algorithms for computational modeling and analysis of protein structures. Further, it offers de novo protein design, enzyme design, ligand docking, and structure prediction of biological macromolecules and macromolecular complexes.
Protein 3D Visualization
- Chimera – a program for the interactive visualization and analysis of molecular structures and related data.
- ChimeraX – It is the next-generation interactive molecular visualization program.
- Swiss-PDB Viewer – Application for analyzing several proteins at the same time as well as protein modeling server.
- PyMol – PyMOL is a molecular visualization system maintained and distributed by Schrödinger.
- VMD – Molecular visualization program for displaying, animating, and analyzing large biomolecular systems using 3-D graphics and built-in scripting.
- RasMol – Molecular visualization tool.
Must Read
Penn Researchers Use Deep Learning to Design Multimodal Antibiotics for Combating Intracellular Infections
The rise of antimicrobial resistance has made treating intracellular infections a significant challenge, as conventional antibiotics often fail to neutralize pathogens hidden within human...
Quantum-Si Unveils ProteoVue™ to Unlock New Frontiers in Protein Variant Detection with Next-Generation Protein...
Single-molecule Next-Generation Protein Sequencing (NGPS) provides a powerful alternative to mass spectrometry for analyzing protein variants, allowing detailed identification of proteoforms and amino acid...
Revolutionizing Drug Discovery: MOLRL Combines Reinforcement Learning and Generative Models for Targeted Molecular Generation
Cellarity, Inc., and NVIDIA have unveiled MOLRL (Molecule Optimization with Latent Reinforcement Learning), a groundbreaking framework for molecular optimization. This approach leverages the latent...
25 New Compounds: How Scripps Research Uses Computer Modeling to Transform Drug Discovery
In an extraordinary feat of chemical synthesis, chemists from Scripps Research have produced 25 picrotoxane molecules. This groundbreaking work combines cutting-edge computational modeling and...
How Evolla is Deciphering the Molecular Language of Proteins with an 80 Billion Parameter...
The complex molecular machinery that make up nature, proteins have evolved over billions of years and are essential to the continuation of life. However,...