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Decoding the Genetic Mechanism of B Chromosome Drive in Rye

Anchal Negi - 0
The extra genetic material, which appears as 'B chromosomes,' has been a riddle for security for many species. They are of least concern for...
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AI

Streamlining High-Throughput Protein Complex Modeling with AlphaPulldown2

Deotima Chakraborty - 0
AlphaPulldown version 2.0, a noteworthy computational biology program that transforms protein structure modeling, is presented by researchers from the European Molecular Biology Laboratory, Hamburg,...
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AI

The G2PT Model: Bridging the Gap Between Genotype and Phenotype Using Hierarchical Transformers

Anchal Negi - 0
Gaining insight into the peculiar relationship between the genes we possess and the characteristics they express is undoubtedly one of the most intriguing quests...
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AI

Evolutionary Scale’s ESM Cambrian: Revolutionizing Protein Understanding at the Scale of Life with Unsupervised Learning

Anchal Negi - 0
Proteins are the most essential molecules for all forms of life on Earth. They perform a vast number of actions vital for life. However,...
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Bioinformatics

DRUG-seq: A Game-Changing Approach to Transcriptional Profiling in Drug Discovery

Dr. Tamanna Anwar - 0
The identification and comprehension of the mechanisms of potential drug compounds is a complex and expensive endeavor in the constantly changing pharmaceutical research landscape....
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AI

AI-Driven Macrocycle Design: How RFpeptides Generate High-Affinity Protein Binders for Diagnostics and Therapeutics

Deotima Chakraborty - 0
Large-scale screening techniques that are resource-intensive and offer limited control on binding mode are usually used to produce macrocyclic binders to therapeutic proteins. There...
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AI

Can InterPLM Decode the Hidden Language of Protein Modeling and Design AI?

Anchal Negi - 0
The emergence of Protein Language Models (PLMs) is changing biological research for the better through efficient prediction of functional annotations and protein structures. However,...
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AI

Learning from Extremophiles: HyperMPNN’s Revolutionary Approach to Thermostable Protein Design

Deotima Chakraborty - 0
Recombinant proteins must be stable in order to be used in biotechnological or medicinal applications. Both the creation of new proteins and the stabilization...
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AI

Unlocking the Power of Single-cell RNA Sequencing with scExplorer

Anchal Negi - 0
With its recent advancements, scRNA sequencing has enabled scientists to view the biological world at the most local of levels- the single cell. Thanks...
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Bioinformatics

Seamless Multi-Omics Integration Made Easy with iModMix

Deotima Chakraborty - 0
Integrating metabolomics with other omics and providing insights into the biology of disease requires bioinformatics competence. Integration is difficult with present approaches, though, as...
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AI

Unlocking Chemical Space: TamGen’s Generative AI Approach for Target-Aware Molecule Generation in Drug Discovery

Deotima Chakraborty - 0
Novel compounds can be discovered in the wide chemical space due to generative drug design that enables one to develop molecules that are effective...
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AI

Exploring New Frontiers in SARS-CoV-2 Research with The Virtual Lab

Anchal Negi - 0
When COVID-19 emerged as a global catastrophe, the scientists had only one goal: to come up with the possible treatments for the virus SARS-CoV-2,...
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AI

RhoFold+: Transforming RNA 3D Structure Prediction with Deep Learning

Deotima Chakraborty - 0
Although RNA 3D structures are important in understanding their functions and in the design of new drugs, their accurate prediction is still a challenge....
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AI

Unlocking the Secrets of RNA: How RNA-GPT is Transforming the Way We Explore and Understand RNA

Deotima Chakraborty - 0
RNAs are crucial molecules that convey genetic information necessary for life, and they have a big impact on biotechnology and medicine development. However, the...
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AI

From Concept to Reality: Efficient Protein Pocket Design with PocketGen

Anchal Negi - 0
Protein pockets have been an integral part of drug discovery for several years and are also targeted during the design of novel molecules. Pockets...
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AI

Evo: A Genomics Foundation Model Redefining Sequence Modeling and Design

Deotima Chakraborty - 0
The DNA sequences of all living organisms hold the fundamental instructions for life. Massive datasets of entire genomes, together with machine learning advancements, may...
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AI

Innovating Through Collaboration: The Protein Engineering Tournament’s Impact on Computational Design

Neermita Bhattacharya - 0
Protein engineering heavily relies on generating sequences using computational models. Limitations such as lack of benchmarking opportunities, scarcity of large protein function datasets, and...
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AI

How BALM is Redefining Binding Affinity Prediction for Unseen Targets and Drugs

Anchal Negi - 0
In the fast-paced world of drug discovery, one of the most crucial aspects is understanding protein-ligand interactions. With the correct algorithms for predicting protein-ligand...
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AI

EPBDxDNABERT-2: A Multi-Modal Deep Learning Model for Enhanced Transcription Factor DNA Binding Prediction

Deotima Chakraborty - 0
It has been demonstrated that there is a functional correlation between transcriptional activity, thermodynamic stability, DNA breathing, and transcription factor (TF) binds. The researchers...
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Biotech

Omega-3 and Omega-6 Fatty Acids: New Allies in Cancer Prevention

Dr. Tamanna Anwar - 0
A groundbreaking new research from the University of Georgia unveils that omega-3 and omega-6 fatty acids may play an integral role in cancer prevention,...
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Unlocking Protein Design with PLAID: A Sequence-Centric Generative Model for All-Atom Structures

Unlocking Protein Design with PLAID: A Sequence-Centric Generative Model for All-Atom Structures

Deotima Chakraborty - 0
The potential influence of generative models for protein design is drawing the attention of the scientific world. However, there are numerous modalities that mediate...
The Nucleotide Transformer: How Foundation Models are Shaping Human Genomics

The Nucleotide Transformer: How Foundation Models are Shaping Human Genomics

Anchal Negi - 0
The field of genomics is ever-changing as a result of an increase in automation and aspects of biological engineering. A groundbreaking study led by...
Protein Language Visualizer: A New Era of Sequence Similarity Exploration

Protein Language Visualizer: A New Era of Sequence Similarity Exploration

Deotima Chakraborty - 0
The availability of biological "big data" and the development of high-throughput sequencing technology have sped up the identification of new protein sequences, making it...
Unlocking the Potential of Equivariant Diffusion Models for Structure-Based Drug Design with DiffSBDD

Unlocking the Potential of Equivariant Diffusion Models for Structure-Based Drug Design with DiffSBDD

Anchal Negi - 0
In the quest to create better and faster methods for drug discovery, a team of innovative researchers from various institutions has developed a groundbreaking...
Harnessing AI for Molecular Discovery: The Promise of Molecular Dynamics Language Models

Harnessing AI for Molecular Discovery: The Promise of Molecular Dynamics Language Models

Deotima Chakraborty - 0
Although molecular dynamics (MD) simulations provide accurate representations of the motion of molecular systems, molecular biology and materials science are challenged by the computational...

CBIRT provides short term training in bioinformatics for students/researchers/life science graduates, etc. The program aims at providing rigourous training required to excel in current dynamic scientific research environment. For more details

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