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Bioimage Analysis Just Got Easier: Unveiling the Power of Omega, the Conversational AI

Anchal Negi - 0
Omega is an open-source software tool that greatly enhances the field of bioimage analysis. Developed by Loïc A. Roy from Chan Zuckerberg Biohub  San...
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AI

Binding Site-driven Molecule Design: BindGPT’s Language Modeling and Reinforcement Learning Powered Generative Framework

Deotima Chakraborty - 0
Understanding the intricate physical interactions between a molecule and its surroundings is necessary to generate unique active molecules for a particular protein, which is...
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AI

Can Diffusion Models Crack the Protein Structure and Docking Code?

Anshika Gupta - 0
The field of protein modeling has witnessed remarkable advances in recent years, particularly with the advent of machine learning techniques. A new review by...
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AI

Introducing the Personal Health LLM: A New Era of Data-Driven Wellness Insights

Deotima Chakraborty - 0
In the field of health, LLM endeavors to concentrate on clinical duties and obtain a diverse array of data. The promise of LLMs in...
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Big Data

Indexing Nature’s Code: A ‘Google for DNA’ to Catalog All Known Biological Sequences

Anchal Negi - 0
Suppose there was a library where the whole instruction manual for every living organism on Earth could be found. It's not science fiction, but...
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AI

Proteome-wide PPI Screening: AlphaFastPPi Paves the Way for Large-scale Studies

Deotima Chakraborty - 0
Despite the challenge of scaling for large-scale screenings, advances in computational structural biology, like AlphaFold-Multimer, have greatly improved the understanding of protein-protein interactions across...
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AI

BioNeMo Folds the Human Proteome: A Fused Dataset of 3D Protein Models for Machine Learning Applications

Anchal Negi - 0
In a recent scientific breakthrough, a team of researchers from NVIDIA and Innophore, USA, came up with a holistic dataset of the predicted protein...
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Antibiotic Resistance

Machine Learning Unveils a Million Potential Antimicrobial Peptides in the Global Microbiome

Deotima Chakraborty - 0
Antibiotic resistance must be addressed immediately with novel antibiotics. By using a large dataset of 63,410 metagenomes and 87,920 prokaryotic genomes from environmental and...
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AI

Advancing Pharmaceutical and Industrial Protein Engineering with StructureGPT’s Innovative Structure-to-Sequence Translation Capabilities

Deotima Chakraborty - 0
Sequence-to-structure predictions are the main focus of current computational methods for reverse translation, which is the process of translating complicated protein structures into sequences....
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AI

The AI Behind the Breakthroughs: Meta Llama 3 NIM and the Future of Healthcare and Life Sciences

Anchal Negi - 0
The healthcare industry is about to change significantly due to the advent of generative AI. Meta Llama 3 NIM, a mighty NVIDIA-developed AI microservice,...
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AI

Charting the Protein Universe with ProTrek’s Tri-Modal Contrastive Learning

Anshika Gupta - 0
Bioinformatics, in its continuous advancement, depends on the detailed examination of proteins within its molecular domain. Proteins, the working structures of the cell, have...
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AI

Leveraging AlphaFold, Rosetta, and Replica-Exchange for Reliable Protein-Protein Docking with AlphaRED

Deotima Chakraborty - 0
Significant progress has recently been made in predicting protein sequence to structure; however, modeling protein interfaces and complex structures is still tricky, particularly when...
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AI

Protein Shapes in Motion: How Diffold Revolutionizes Conformation Sampling

Anchal Negi - 0
Our cells are supported critically by proteins, which are also highly affected by their 3D structure. The triumph in computational biology is the ability...
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Bioinformatics

MultiRNAflow: A Comprehensive Tool for Temporal RNA-seq Data Analysis in Multiple Biological Conditions

Deotima Chakraborty - 0
RNA sequencing is currently a useful tool for studying the dynamic transcriptional mechanisms that control the operation of eukaryotic cells. Nevertheless, complicated experimental designs...
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AI

Predicting Multiple Conformations and Ensembles with AFsample2: An AlphaFold2 Extension

Anshika Gupta - 0
Acting as enzymes, structural elements, and molecular motors, proteins represent the molecular drive of biological systems, the elucidation of which relies on the explication...
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Bioinformatics

Simplifying Single-cell Metadata Exploration with LotOfCells

Anchal Negi - 0
Single-cell RNA sequencing (scRNA-seq) has brought a revolution in biological research by granting scientists a look into the mechanisms inside individual cells within a...
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AMR Alert

Outsmarting the Malaria Parasite: SMART Researchers Decode the Mystery of Drug Resistance Mechanism

Anshika Gupta - 0
Artemisinin, which is used as a cure for malaria, has remained an effective drug in managing the disease over the years. However, the recent...
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AI

No Coding Required! SaprotHub Brings Protein Modeling to Every Biologist

Deotima Chakraborty - 0
Users without prior Machine Learning (ML) experience have difficulties when it comes to training and implementing deep learning models. Regardless of prior experience with...
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AI

Breaking New Ground in RNA Structure and Sequence Design with RNAFlow

Anchal Negi - 0
Unsung heroes of our cells are RNAs. These molecules are responsible for many biological processes, from carrying hereditary material to controlling protein production. However,...
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AMR Alert

Oxford Researchers Develop Game-changing Small Molecule to Suppress the Evolution of Antibiotic Resistance

Anshika Gupta - 0
Antibiotic resistance is one of the most pressing challenges in modern medicine. As bacteria evolve to withstand our best treatments, once-manageable infections are becoming...
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FoldToken2: Decoding Proteins with a New Compact Language

FoldToken2: Decoding Proteins with a New Compact Language

Anchal Negi - 0
Scientists at Westlake University have developed FoldToken2, a novel approach to protein structure representation that is capable of surpassing the coordinates. This innovative method...
Unlocking New Dimensions in AI-Driven Drug Discovery: TopoFormer Merges Topology and Transformers for Protein-ligand Interaction Predictions

Unlocking New Dimensions in AI-Driven Drug Discovery: TopoFormer Merges Topology and Transformers for Protein-ligand...

Deotima Chakraborty - 0
Transformers have shown promise in computational biology, but applying them to biological sequences could cause mispredictions in the downstream processes. A greater range of...
Can Computationally Designed Membrane Protein Analogs Accelerate Drug Discovery?

Can Computationally Designed Membrane Protein Analogs Accelerate Drug Discovery?

Deotima Chakraborty - 0
It is still very difficult to construct complex protein folds from scratch using only computational methods. École Polytechnique Fédérale de Lausanne (EPFL) scientists create...
Breaking Barriers in DNA Research: CGeNArate - A Simplified Model for Complex Simulations

Breaking Barriers in DNA Research: CGeNArate – A Simplified Model for Complex Simulations

Anchal Negi - 0
Researchers from the Institute for Research in Biomedicine (IRB Barcelona) introduce CGeNArate, a short sequence-dependent coarse-grained model for DNA simulations. CGeNArate solves the challenge...
Streamlining Drug Discovery: How SPARROW Picks the Most Promising Molecules

Streamlining Drug Discovery: How SPARROW Picks the Most Promising Molecules

Anshika Gupta - 0
In the world of molecular design that is constantly evolving, it is always essential to ensure that along with the structure and properties of...

CBIRT provides short term training in bioinformatics for students/researchers/life science graduates, etc. The program aims at providing rigourous training required to excel in current dynamic scientific research environment. For more details

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