Saturday, December 21, 2024

BIOINFORMATICS TOOLS

Gene Prediction

  • GENEID – A program to predict genes, exons, splice sites and other signals along a DNA sequence.
  • AUGUSTUS – Program that predicts genes in eukaryotic genomic sequences.
  • EuGene – Integrative gene finder for eukaryotic and prokaryotic genomes.
  • PseudoPipe – A stand alone computational pipeline for pseudogene annotation.
  • GenScan – Web server for the identification of complete gene structures in genomic DNA.
  • HMMgene – 1.1 – Program for prediction of vertebrate and C. elegans genes.

Must Read

FedPyDESeq2: Advancing Differential Expression Analysis with Federated Learning for Bulk RNA-Seq.

FedPyDESeq2: Advancing Differential Expression Analysis with Federated Learning for Bulk RNA-Seq

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In genomics, the conventional approach for explaining any gene expression is to cross-analyze bulk RNA sequencing (RNA-seq) data. However, as researchers, more often than...
Decoding Protein Roles with ProCyon: A Unified Framework for Multiscale Phenotypes

Decoding Protein Roles with ProCyon: A Unified Framework for Multiscale Phenotypes

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About 20% of human proteins lack recognized functionalities, and over 40% lack context-specific functionals, underscoring the difficulties of comprehending these proteins and their varied...

Streamlining Copy Number Variation Discovery: How CNV-Finder is Changing Genomics

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A prevailing challenge in genomics still revolves around the comprehension of structural variants, one of which is copy number variation (CNV). To undertake the...
Unlocking Protein Design with PLAID: A Sequence-Centric Generative Model for All-Atom Structures

Unlocking Protein Design with PLAID: A Sequence-Centric Generative Model for All-Atom Structures

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The potential influence of generative models for protein design is drawing the attention of the scientific world. However, there are numerous modalities that mediate...
The Nucleotide Transformer: How Foundation Models are Shaping Human Genomics

The Nucleotide Transformer: How Foundation Models are Shaping Human Genomics

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The field of genomics is ever-changing as a result of an increase in automation and aspects of biological engineering. A groundbreaking study led by...