Sunday, June 22, 2025

BIOINFORMATICS TOOLS

Phylogenetic Analysis

  • MEGA – Molecular Evolutionary Genetics Analysis package. It is a computer software for conducting automatic and manual sequence alignment and constructing phylogenetic trees.
  • Phylip – It is a free package of programs for inferring phylogenies.
  • PAML – A package of programs for phylogenetic analyses of DNA or protein sequences using maximum likelihood.
  • DAMBE – Software package for extensive Data Analysis in Molecular Biology and Evolution
  • iTOL – Interactive Tree Of Life is an online tool for the display, annotation and management of phylogenetic and other trees.

Must Read

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D-I-TASSER Outperforms AlphaFold? A New Frontier in Protein Structure Modeling

D-I-TASSER Outperforms AlphaFold? A New Frontier in Protein Structure Modeling

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Unlocking Biomolecular Secrets with AF3Score: A Leap Forward in Structural Evaluation

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Researchers from Changping Laboratory in Beijing introduced AF3Score, a novel adaptation of AlphaFold3 designed to evaluate biomolecular structures with unprecedented accuracy. This innovation addresses...
Overlapping Genes, Unfolding Insights: Synthetic Biology Meets AI

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Given that the sharing of codon nucleotides dramatically reduces the size of protein sequences, viruses in nature often generate overlapping genes (OLG) in alternate...
PhysDock: A New Era in Protein-Ligand Docking with AI and Physics

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In a breakthrough that could transform drug discovery, a team of researchers from ShanghaiTech University has introduced PhysDock, a novel AI-powered model designed to...