What If Molecular Simulations Could Run 10,000 Times Faster?
Conventional molecular dynamics (MD) simulations provide atomistic insights into molecular behavior but are fundamentally limited by their femtosecond time steps, making it computationally challenging...
How D&D-seq Is Making Hard-to-Detect DNA-Protein Interactions Visible
If you've ever tried to figure out exactly where a transcription factor sits down on the genome inside a single cell, you know it's...
BioReason-Pro Allows Structured Reasoning for Protein Function Predictions
A team of scientists from the University Health Network - Canada's Hospital, Arc Institute and Vector Institute developed BioReason-Pro to tackle one of the...
PPIscreenML: A Rigorous Machine Learning Approach to Screening Protein-Protein Interactions with AF2
Every second, thousands of proteins inside your cells are bumping into each other, forming fleeting partnerships, and splitting apart again. These protein-protein interactions (PPIs)...
Meet FrustrAI-Seq: Proteome-Wide Frustration Profiling Without Structural Inputs
Proteins are remarkable molecules. They fold, bend, bind, and catalyze, all while balancing an internal tension that most biology textbooks barely mention. That tension...