Top bioinformatics software, tools and libraries!

List of Bioinformatics software, resources, and libraries for Bioinformatics Analysis, Data Processing, Next Generation Sequencing Data Analysis and much more.

Bioinformatics

Bioinformatics Software, Resources, and Libraries A curated list of awesome Bioinformatics software, resources, and libraries for Data Processing, Next Generation Sequencing Data Analysis and much more. Mostly command line based, and free or open-source.

pythonidae

Collection of tools and resources for bioinformatics, genomics, agriculture, food science, medicine, genetic engineering, etc.

PyRice

A Python package for query rice gene information

GEM

Genome wide Event finding and Motif discovery. High resolution peak calling and motif discovery for ChIP-seq and ChIP-exo data.

Must Read

Claude Opus 4.5

Claude Opus 4.5 and the Future of AI-Driven Research in Healthcare and Biotechnology

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The growing complexity of biomedical research and healthcare demands AI systems that can go beyond general assistance to support end-to-end scientific workflows. Building on...
DrugCLIP

DrugCLIP Enables High-Throughput Virtual Screening Across the Human Proteome

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Researchers at Tsinghua University have introduced DrugCLIP, a contrastive learning framework that enables ultrafast and accurate virtual screening at a genome-wide scale. Published in...
FoldMason

Beyond the Sequence: How FoldMason is Redefining Multiple Protein Structure Alignment at Scale

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The authors at Seoul National University developed FoldMason, a free, open-source, progressive Multiple Structural Alignment (MSTA) method published in Science that uses a structural...
BindEvaluator and moPPIt

De Novo Peptide Binder Generation: How moPPIt Targets ‘Undruggable’ Proteins

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Authors from the University of Pennsylvania and others innovated the motif-specific PPI targeting algorithm (moPPIt), a computational framework that integrates BindEvaluator along with Multi-Objective...
DNA-Diffusion

Generating DNA Sequences Using AI: DNA-Diffusion Promises Effective Gene Therapy

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The researchers at Broad Institute and Mass General Brigham in Nature Genetics propose DNA-Diffusion, the first ever generative diffusion framework trained on DNA accessibility...