NGS Data Analysis for Beginners: The Pipeline, Tools and First Commands
A beginner’s guide to NGS data analysis: the pipeline from FASTQ reads to annotated variants, the tools at each step, starter commands and free practice data.
- Bioinformatics | Data Analysis | News | Paper Summary | RNA-Seq | Statistics | Tools | Trending
Simplifying Single-cell Metadata Exploration with LotOfCells
Single-cell RNA sequencing (scRNA-seq) has brought a revolution in biological research by granting scientists a look into the mechanisms inside individual cells within a population. It is an incredible technology that is also challenging due to the huge amount of data generated. One critical aspect of scRNA-seq analysis involves comparing cell type proportions across conditions….
- Bioinformatics | Genomics | News | NGS | Paper Summary | Transcriptomics | Trending
Choosing the Best Tool for Identifying Transcriptional Regulators: Navigating the NGS Landscape
This article delves into a recent study undertaken by a team of researchers that examined multiple computer algorithms for transcriptional regulator prediction using Next-Generation Sequencing (NGS) data. Grasping biological processes and developing personalized medications necessitates a deep understanding of gene control. Transcriptional regulators (TRs) control the expression of certain genes, and NGS technology has enabled…
- Bioinformatics | Cell | News | NGS | Paper Summary | RNA-Seq | Tools
Unlock Cellular Mysteries with IndepthPathway: An Innovative Tool for Single-cell Sequencing Pathway Enrichment Analysis
Researchers from the University of Pittsburgh, USA, have made a momentous breakthrough in the realm of single-cell sequencing with the creation of IndepthPathway, an innovative method for pathway enrichment analysis from scRNA-seq data. Overcoming the challenges posed by high noise and low gene coverage in single-cell sequencing, this tool employs the Weighted Concept Signature Enrichment Analysis…
