Cryo-EM

Scientists of the DeepTracer project have formulated DeepTracer-refine, an automated pipeline that consolidates the advantages of sequence-to-model and map-to-model strategies, complements their shortcomings, and aspires to refine Alphafold2-generated structures through amelioration of the regions with lesser confidence by splitting AlphaFold’s structure into compact domains and manually docking them into experimental maps to fix the residue…