Covid-19

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USC Researchers Unveil METAGENE-1: Advancing Pathogen Detection and Pandemic Monitoring
ByAnchal Negi January 11, 2025October 22, 2026

In the ever-evolving world of infectious diseases, early detection and monitoring play a critical role in combating pandemics. In a groundbreaking collaboration, researchers from the University of Southern California, Prime Intellect, and the Nucleic Acid Observatory have unveiled METAGENE-1, a state-of-the-art metagenomic foundation model designed to transform public health monitoring and pathogen detection. This innovative…

Read More USC Researchers Unveil METAGENE-1: Advancing Pathogen Detection and Pandemic Monitoring
Infectious Diseases | News | Trending | Virus

Human Metapneumovirus (HMPV): A Hidden Respiratory Threat or Just Another Cold Virus?
ByDr. Tamanna Anwar January 8, 2025October 22, 2026

Human Metapneumovirus (HMPV) is a respiratory virus that has recently gained prominence in public health discussions, particularly due to outbreaks in various regions, including China and India. First identified in 2001 by Dutch researchers, HMPV belongs to the Paramyxoviridae family, which includes other significant respiratory pathogens like Respiratory Syncytial Virus (RSV). While the virus was…

Read More Human Metapneumovirus (HMPV): A Hidden Respiratory Threat or Just Another Cold Virus?
AI | Bioinformatics | COVID-19 | Drug Discovery | LLM | News | Paper Summary | Trending

Exploring New Frontiers in SARS-CoV-2 Research with The Virtual Lab
ByAnchal Negi November 28, 2024October 22, 2026

When COVID-19 emerged as a global catastrophe, the scientists had only one goal: to come up with the possible treatments for the virus SARS-CoV-2, which was quickly changing its form. Now, scientists appear to be harnessing the potential of artificial intelligence (AI) to explore unexplored territories in science. One such approach introduced by Stanford University…

Read More Exploring New Frontiers in SARS-CoV-2 Research with The Virtual Lab
Covid-19 News | Health | Infectious Diseases | News | Paper Summary | SARS-CoV-2 | Trending | Virus

Long COVID: Understanding the Lingering Effects of COVID-19
ByAnchal Negi August 12, 2024October 22, 2026

The COVID-19 pandemic has undoubtedly caused a lasting impact on the world. Millions of people worldwide are still struggling with the aftermath of COVID-19, which is increasingly referred to as Long COVID. Healthcare professionals and scientists across the globe are increasingly worried about this complex syndrome. The scale and intricacy of this post-viral condition have…

Read More Long COVID: Understanding the Lingering Effects of COVID-19
Bioinformatics | COVID-19 | Disease Diagnosis | Infectious Diseases | News | Transcriptomics | Trending

Transforming Infection Diagnosis: Saliva-Based mRNA Biomarker for Accurate Detection
ByDr. Tamanna Anwar November 26, 2023November 26, 2023

Since the COVID pandemic began, the world has been reminded of the poor reliability of elevated body temperature for detecting infections. Even when infected with SARS-CoV-2, many patients exhibit no fever. But while obvious symptoms can be absent, infections trigger host gene responses at sites harboring pathogens and in distant cells receiving molecular signals. Leveraging…

Read More Transforming Infection Diagnosis: Saliva-Based mRNA Biomarker for Accurate Detection
Bioinformatics | Covid-19 News | Drug Discovery | Infectious Diseases | News | Paper Summary | Trending | Virus

The Rise of mRNA Vaccines: A Game-Changer for Public Health?
BySwasti Tyagi October 9, 2023January 25, 2024

The emergence of mRNA vaccine technology represents a monumental leap forward in disease prevention. A review article published in Nature Reviews Drug Discovery by researchers at the University of Pennsylvania and Carnegie Mellon University discusses the evolution of messenger RNA (mRNA) based vaccines over the course of the past few years. The powerful effects of…

Read More The Rise of mRNA Vaccines: A Game-Changer for Public Health?
AI | Bioinformatics | COVID-19 | Covid-19 News | Drug Discovery | News | Paper Summary | SARS-CoV-2 | Structural Biology | Tools | Trending

Brock Researchers Develop AI-Powered Tool ‘DAPTEV’ to Design New Aptamer Drugs for COVID-19
ByNeegar Naushaba Iqbal August 5, 2023October 22, 2026

Traditional drug discovery and development methods are quite expensive, cumbersome, and prone to the biases of experts. A revolution in the field of drug development has emerged in the form of aptamers. Aptamers are single-stranded oligonucleotides (DNA/RNA) capable of binding to biomolecules with high affinity as well as specificity. However, the conventional process of aptamer…

Read More Brock Researchers Develop AI-Powered Tool ‘DAPTEV’ to Design New Aptamer Drugs for COVID-19
Bioinformatics | Biomedical Engineering | Corona Virus | COVID-19 | Covid-19 News | Health | Infectious Diseases | Machine Learning | News | Paper Summary | Trending

Scientists Introduce ‘GeNose C19’ a Quick Screening Tool for Sniffing Out COVID-19 Based on Exhaled Breath-print Recognition
ByTanveen Kaur August 19, 2022August 19, 2022

Universitas Gadjah Mada, Indonesia, scientists developed a low-cost, non-invasive method to rapidly sniff out COVID-19 by using an electronic nose named “GeNose C19”. The method of RT-qPCR, which stands for a reverse transcription-quantitative polymerase chain reaction, has been widely utilized to identify the SARS-CoV-2 virus that causes COVID-19. However, clinicians frequently prefer to use a…

Read More Scientists Introduce ‘GeNose C19’ a Quick Screening Tool for Sniffing Out COVID-19 Based on Exhaled Breath-print Recognition
Bioinformatics | Cancer Research | Computational Models | COVID-19 | Covid-19 News | Drug Discovery | News | OMICS | Paper Summary | Trending

iLINCS: An Integrative Web-based Platform for Analysis of OMICS Data and Signatures of Cellular Perturbations
ByTanveen Kaur August 15, 2022October 22, 2026

The University of Cincinnati scientists introduce iLINCS, an integrative web-based platform for analyzing OMICS data and markers of cellular disturbances. The user-friendly interfaces of iLINCS allow for the execution of sophisticated omics signature analyses, mechanism of action analysis, and signature-driven drug repositioning. Only a few systems exist that combine several omics data types, bioinformatics tools,…

Read More iLINCS: An Integrative Web-based Platform for Analysis of OMICS Data and Signatures of Cellular Perturbations
Bioinformatics | Corona Virus | COVID-19 | Deep Learning | Drug Discovery | Health | Infectious Diseases | News | Paper Summary | Structural Biology | Trending

Hierarchical Structure-based Virtual Screening Targeting SARS-CoV-2 Endoribonuclease
BySrishti Sharma August 6, 2022October 22, 2026

Since the first appearance of SARS-CoV-2, a number of in silico methods have been employed to discover possible drugs that can target the viral life cycle. Scientists from National Research Centre, Egypt, targeted Endoribonuclease, which is one of the crucial non-structural proteins since it is responsible for processing viral RNA to escape detection by the…

Read More Hierarchical Structure-based Virtual Screening Targeting SARS-CoV-2 Endoribonuclease
Bioinformatics | Corona Virus | COVID-19 | Covid-19 News | Genomics | News | NGS | Paper Summary | Sequencing | Trending

Scientists Devised a Bioinformatics Method ‘COJAC’ for Early Detection and Surveillance of SARS-CoV-2 Genomic Variants in Wastewater
ByTanveen Kaur July 21, 2022November 11, 2022

Using read pairs with several SARS-CoV-2 variant-specific signature mutations as a reliable signal of low-frequency variants, scientists develop the bioinformatics technique known as COJAC (Co-Occurrence adjusted Analysis and Calling). The genomic sequencing, in conjunction with COJAC, can offer population-level estimates of the prevalence and fitness of emerging variants from wastewater samples earlier and on the basis…

Read More Scientists Devised a Bioinformatics Method ‘COJAC’ for Early Detection and Surveillance of SARS-CoV-2 Genomic Variants in Wastewater
Bioinformatics | Corona Virus | COVID-19 | Covid-19 News | News | Structural Biology | Trending

Contact Perturbation Analysis of the SARS-CoV-2 Delta Variant Singular Interface Dynamics
ByTanveen Kaur July 16, 2022November 11, 2022

Scientists demonstrate that L452R and T478K mutations in the Delta variant interact synergistically with nearby residues to cause significant alterations in the spike/ACE2 interface, suggesting a single mode of action. Understanding the molecular distinctions of emerging SARS-CoV-2 variants is essential because they raise questions about the capacity to endure the Covid-19 pandemic. Using crystallographic structures…

Read More Contact Perturbation Analysis of the SARS-CoV-2 Delta Variant Singular Interface Dynamics
Bioinformatics | COVID-19 | Drug Discovery | Gene Expression | Genomics | GWAS | Machine Learning | News | OMICS | Paper Summary | Trending

Transcriptome-Wide Association Studies Integrated with 3D Genomic and Epigenomic Data used to Improve Target Gene Discovery and Drug Repurposing
ByTanveen Kaur June 13, 2022October 22, 2026

Scientists from Pennsylvania State University integrated 3D genomic and epigenomic data with transcriptome-wide association studies data to improve gene expression predictions. The researchers propose an integrative method PUMICE that integrates 3D genomic and epigenomic data with expression quantitative trait loci (eQTL) to predict gene expressions more accurately. An extension of the method PUMICE +, also combines transcriptome-wide…

Read More Transcriptome-Wide Association Studies Integrated with 3D Genomic and Epigenomic Data used to Improve Target Gene Discovery and Drug Repurposing
Bioinformatics | Corona Virus | COVID-19 | Covid-19 News | Drug Discovery | News | Structural Biology | Trending

Scientists Develop Hybrid Molecules by Drug Repurposing in an Effort to Design New Drugs to Treat Covid-19
ByDr. Tamanna Anwar May 26, 2022October 22, 2026

Controlling the spread of the highly contagious disease and protecting human health requires developing new medications that stay effective against growing COVID-19 variations. After spending more than two years studying SARS-CoV-2, the virus that causes COVID-19, the researchers at the Department of Energy’s (DOE) Oak Ridge National Laboratory (ORNL) are designing and testing small-molecule antivirals…

Read More Scientists Develop Hybrid Molecules by Drug Repurposing in an Effort to Design New Drugs to Treat Covid-19
Bioinformatics | Biotech | Corona Virus | COVID-19 | Covid-19 News | News | Trending

SARS-CoV-2 Delta Variant’s Unique Binding Leads to High Transmissibility
ByDr. Tamanna Anwar May 13, 2022June 18, 2022

The National Institutes of Health’s discovery could lead to new approaches to tackle future SARS-CoV-2 variants. According to a study by experts at the National Institutes of Health, unlike other SARS-CoV-2 variants, the Delta variant can bind to copies of itself, generating larger aggregations, or clumps, of virus particles. According to the researchers, this connecting…

Read More SARS-CoV-2 Delta Variant’s Unique Binding Leads to High Transmissibility
Bioinformatics | COVID-19 | Covid-19 News | Drug Discovery | News | Paper Summary

Scientists Revealed the Human Genetic Epidemiology of the COVID-19 Disease
ByTanveen Kaur May 12, 2022October 22, 2026

Scientists from the University of Helsinki, Broad Institute, and Harvard Medical School have revealed the human genetic epidemiology of the COVID-19 disease caused by SARS-CoV-2. The study indicates that the genetic association studies have been particularly fast in conveying new genetic signals underlying COVID-19 severity and disease susceptibility and can advance the treatment significantly. Human…

Read More Scientists Revealed the Human Genetic Epidemiology of the COVID-19 Disease
Bioinformatics | Corona Virus | COVID-19 | Covid-19 News | Drug Discovery

Repurposing FDA Approved Asthma Drug to Block Crucial SARS-CoV-2 Protein
ByDr. Tamanna Anwar May 2, 2022October 22, 2026

In a new study by scientists from the Indian Institute of Science (IISc), repurposing a drug used to treat asthma and allergies has been shown to bind and block a critical protein produced by the virus SARS-CoV-2, reducing viral replication in human immune cells. The US Food and Drug Administration (FDA) approved drug, montelukast, has…

Read More Repurposing FDA Approved Asthma Drug to Block Crucial SARS-CoV-2 Protein
AMR Alert | Antibiotic Resistance | COVID-19 | Covid-19 News | Drug Discovery | Paper Summary | Precision Medicine

Benefits and Challenges of ‘One-Size-Fits-All’ Anti-Tuberculosis Treatment Strategies
ByTanveen Kaur May 1, 2022October 22, 2026

An expert scientist affiliated with the Center for Discovery and Innovation and a colleague from Harvard T.H. Chan School of Public Health discussed the challenges and priorities in the anti-tuberculosis treatment strategies and drug development. The study published in Nature Reviews Microbiology this week suggests that the preclinical and clinical anti-tuberculosis treatment methodologies depicted in…

Read More Benefits and Challenges of ‘One-Size-Fits-All’ Anti-Tuberculosis Treatment Strategies
Bioinformatics | Corona Virus | COVID-19 | Covid-19 News | Machine Learning | News | Trending

Scientists Develop a Machine Learning Model to Predict the Evolution of an Epidemic Accurately
ByDr. Tamanna Anwar April 28, 2022June 18, 2022

Machine learning algorithms can provide precise forecasting of virus propagation during pandemics. This method eliminates human bias and assumptions, allowing for a more accurate prediction of pandemic evolution. Researchers from KAUST developed a dynamic machine learning model with an efficient forecasting approach that can predict confirmed and recovered COVID-19 times series data with high accuracy….

Read More Scientists Develop a Machine Learning Model to Predict the Evolution of an Epidemic Accurately
AI | Bioinformatics | Corona Virus | COVID-19 | Covid-19 News | Data Science | Deep Learning | Featured | Machine Learning | Paper Summary | Trending

Scientists Developed a Hybrid Machine Learning/Deep Learning Based Covid-19 Severity Prediction Model to Support Clinical Decision Making
ByTanveen Kaur March 23, 2022November 9, 2022

Scientists from Fondazione Poliambulanza Istituto Ospedaliero, Italy, developed a hybrid machine learning/deep learning model to classify patients in two outcome categories, non-ICU, and ICU. With the likelihood score belonging to an outcome class and case-based SHAP interpretation of feature importance, the model intends to give clinical decision support to medical physicians. The scientists devised a…

Read More Scientists Developed a Hybrid Machine Learning/Deep Learning Based Covid-19 Severity Prediction Model to Support Clinical Decision Making
Bioinformatics | Corona Virus | COVID-19 | Covid-19 News | Machine Learning | Paper Summary | Trending

COVID-19 Phytochemical Drug Discovery with High-Resolution Computational Docking and Machine Learning Enabled Binder Prediction
BySwati Yadav February 11, 2022November 25, 2023

The researchers at Michigan State University in the United States used extensive structural datasets along with a refined and annotated collection of antiviral phytochemicals to determine which naturally derived medicines have the best chance of provoking strong binding interactions with SARS-CoV-2 proteins and thus preventing or disrupting the viral infection process. Millions of people have…

Read More COVID-19 Phytochemical Drug Discovery with High-Resolution Computational Docking and Machine Learning Enabled Binder Prediction
Bioinformatics | Corona Virus | Network Modeling | Structural Biology | Trending

Network Based Computer Modeling Revealed Omicron’s Mechanism of Escaping Antibodies
ByDr. Tamanna Anwar February 3, 2022June 18, 2022

According to a computational study carried out by researchers at MIT, several mutations in the virus’ spike protein enable it to dodge antibodies that target SARS-CoV-2. A new study published in the journal Cell Reports Medicine shows that the Omicron variant’s spike protein has dozens of mutations that let it elude all four types of…

Read More Network Based Computer Modeling Revealed Omicron’s Mechanism of Escaping Antibodies
Biotech | Corona Virus | Trending

Antibodies that can block Omicron variant of Covid-19 identified
ByDr. Tamanna Anwar January 2, 2022October 22, 2026

Antibodies have been found that neutralize Omicron and other coronavirus strains by targeting areas that stay largely unchanged as the virus mutates have been discovered. The findings, published in the journal Nature, might aid in the development of vaccines and antibody therapies that are effective not only against Omicron but also against additional variants that…

Read More Antibodies that can block Omicron variant of Covid-19 identified

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Covid-19

Scientists Revealed the Human Genetic Epidemiology of the COVID-19 Disease

Repurposing FDA Approved Asthma Drug to Block Crucial SARS-CoV-2 Protein

Benefits and Challenges of ‘One-Size-Fits-All’ Anti-Tuberculosis Treatment Strategies

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