Unraveling the Pangenome: Pangene Graphs Enables Comprehensive Gene Content Analysis Across Diverse Organisms
In genomics, we need to understand the gene content of an organism to understand its true biology. This is essential for large eukaryotic genomes, such as the human genome, which encompasses approximately 20,000 protein-coding genes. Currently, tools have been developed to identify gene content changes in bacterial genomes, but none apply to the human pangenome….
