Modeling New Mutational Spaces with Machine Learning
From cancer and autoimmune diseases to allergies and neurodegenerative diseases, antibody therapeutics are being used to treat human conditions. Molecular properties of antibodies, such as their high affinities, long half-lives, potent effector functions, and excellent biophysical properties (i.e., high stability and solubility), contribute significantly to the success of antibody therapeutics. Antigen-specific monoclonal antibodies (mAbs) may…