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Scientists Devised a Bioinformatics Method ‘COJAC’ for Early Detection and Surveillance of SARS-CoV-2 Genomic Variants in Wastewater
Using read pairs with several SARS-CoV-2 variant-specific signature mutations as a reliable signal of low-frequency variants, scientists develop the bioinformatics technique known as COJAC (Co-Occurrence adjusted Analysis and Calling). The genomic sequencing, in conjunction with COJAC, can offer population-level estimates of the prevalence and fitness of emerging variants from wastewater samples earlier and on the basis…
