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Scientists Develop a New Computational Tool ‘Grit’ to Identify Upstream Transcription Factor Binding Sites More Accurately
Scientists from Yangtze University, Jingzhou, China developed a computational tool, “Grit,” to identify the upstream transcription factor binding sites in orthologous genes by the utilization of mixed Student’s t-test statistics. The transcription factor (TF) regulates the transcription of DNA to messenger RNA or mRNA by binding to upstream sequence motifs. Distinguishing the locations of known…