PARP Inhibition

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Integrative Multi-Omics Analysis Reveals Molecular Responses to PARP Inhibition: A Focus on Thermal Proteome Profiling
ByPrachi Khare October 1, 2023October 1, 2023

Understanding diverse molecular mechanisms is necessary for the research of complex diseases. Using COSMOS, the integration of Thermal Proteome Profiling (TPP) with phosphoproteomics and transcriptomics provides a comprehensive perspective of biological activities. The technique emphasized the importance of TPP in functional proteomics by discovering both well-known and novel molecular responses to Poly (ADP-ribose) polymerases (PARPs)…

Read More Integrative Multi-Omics Analysis Reveals Molecular Responses to PARP Inhibition: A Focus on Thermal Proteome Profiling

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