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Ameliorating the Chromatin Landscape: ChromaFold’s Accurate 3D Contact Map Prediction from scATAC-seq Data
USA-based researchers have formulated a supervised deep learning model, ChromaFold, that has achieved state-of-the-art performance in cell-type-specific prediction of 3D contact maps and regulatory interactions only utilizing single-cell ATAC sequencing (scATAC-seq) data, bypassing the prerequisite of multiple input data modalities. Additionally, the lightweight architecture of ChromaFold brings compatibility with standard GPUs; its ability to make…
