BERT

Scientists from the University of Southern Denmark, NaturalAntibody and Alector Therapeutics unveil nanoBERT, a nanobody-specific transformer designed to predict amino acids in specific positions within query sequences. NanoBERT outperforms human-based language models and ESM-2, demonstrating the benefits of domain-specific language modeling. Fine-tuning on thermostability datasets shows promise for engineering therapeutic nanobodies. Nanobodies, also known as…