D-I-TASSER Outperforms AlphaFold? A New Frontier in Protein Structure Modeling
The requirement and utility of conventional force field-based folding simulations have been called into question by the overwhelming success of deep learning techniques in protein structure prediction. Researchers from the University of Michigan and the National University of Singapore presented a hybrid method called deep-learning-based iterative threading assembly refinement (D-I-TASSER), which combines iterative threading fragment…
