{"id":6446,"date":"2022-06-25T06:00:00","date_gmt":"2022-06-25T00:30:00","guid":{"rendered":"https:\/\/cbirt.net\/staging\/?p=6446"},"modified":"2022-07-02T01:11:53","modified_gmt":"2022-07-01T19:41:53","slug":"applying-3d-computational-simulation-to-reveal-the-secrets-of-the-genome-structure-in-the-human-cell-nucleus","status":"publish","type":"post","link":"https:\/\/cbirt.net\/staging\/applying-3d-computational-simulation-to-reveal-the-secrets-of-the-genome-structure-in-the-human-cell-nucleus\/","title":{"rendered":"Applying 3D Computational Simulation to Reveal the Secrets of the Genome Structure in the Human Cell Nucleus"},"content":{"rendered":"\n

A research team from Nagoya University in Japan has created a 3-Dimensional computational simulation of the formation of the genome structure in the human cell nucleus. The model is expected to help in understanding cellular regulatory mechanisms and diseases like cancer that modify DNA.<\/p>\n\n\n

\n
\"genome
Image Description: New modeling technique provides a platform to investigate the relationship between the structure, dynamics, and functions of the human genome  (Credit: Shin Fujishiro and Masaki Sasai)
Image Source: https:\/\/www.nagoya-u.ac.jp\/researchinfo\/result-en\/2022\/06\/20220623-01.html<\/figcaption><\/figure>\n<\/div>\n\n\n

Because it influences DNA reading and replication, the three-dimensional shape of the genome is crucial in controlling how animal and plant cells use their DNA. Our understanding of genome organization has improved as a result of the recent development of tools like high-throughput chromosomal conformation capture (Hi-C and related methods), electron microscopy, and superresolution microscopy. It is essential to create trustworthy computational models that can span these many experimental paradigms to elucidate the mechanisms governing genome organization further.<\/p>\n\n\n\n

By studying the entire human cell genome, Shin Fujishiro and Masaki Sasai, Professor Emeritus of Nagoya University’s Department of Complex Systems Science, Graduate School of Informatics, created a 3D model. Using the model as a foundation, they investigated the connection between the structure, dynamics, and functions of the human genome. The research results were published in the Proceedings of the National Academy of Sciences of the United States of America’s online edition.<\/p>\n\n\n\n

According to Professor Sasai, the spatial arrangement of DNA and its dynamic activity in cells are crucial for understanding the functioning of the cell. While many experimental techniques, including biochemical and microscopy technologies, have been developed to help researchers understand how DNA is organized in cells, but now a comprehensive picture is required. Thus, the first computational model capable of quantitatively analyzing various data from the complete genome of human cells is presented in this research.<\/p>\n\n\n\n

The researchers looked into chromatin to better understand the mechanism. In order to preserve the DNA compact, cells produce chromatin, a mixture of DNA and proteins. In line with their idea, chromatin is misplaced and undergoes an unfolding process during cell division that causes repulsive forces to drive the chromatin chains to split apart. The nuclei’s chromatin is divided into active and inactive compartments by the same force. The researchers discovered that the proposed mechanism clarified biochemical and microscopic findings of prior studies.<\/p>\n\n\n

\n
\"genome
Image Description: Generation of dynamic three-dimensional genome structure through phase separation of chromatin.
Image Source: https:\/\/www.nagoya-u.ac.jp\/researchinfo\/result-en\/2022\/06\/20220623-01.html<\/figcaption><\/figure>\n<\/div>\n\n\n

The simulated genome grew upon entering the G1 phase in accordance with the heterogeneous repulsion between chromatin chains, which transported chromatin heterogeneously and caused phase separation of chromatin. This repulsion-driven phase separation accurately predicts the dynamic fluctuations of the nuclei of various human cells and quantitatively replicates the chromatin domains, A\/B compartments, lamina-associated domains, and nucleolus-associated domains that have been found in experiments. The researchers suggest that the dynamic genome’s organization is substantially determined by phase separation brought on by diverse repulsive interactions between chromatin chains.<\/p>\n\n\n\n

Professor Sasai explains that this model offers a useful resource and a novel viewpoint in cell biology. The model can be used to infer how cell disturbances alter the dynamics and organization of the genome from the computer model created in this study. It can also be used to look into how cancer cells and other illness cells influence the DNA. It enables a more thorough examination of the connection between genomic structure and transcriptional control. The model developed in the research offers a vital tool and a fresh perspective on cell biology.<\/p>\n\n\n\n

Story Source:<\/em> Shin, F., & Masaki, S. (2022). Generation of dynamic three-dimensional genome structure through phase separation of chromatin. Proceedings of the National Academy of Sciences<\/em>, 119<\/em>(22), e2109838119. DOI: 10.1073\/pnas.2109838119<\/a> https:\/\/www.nagoya-u.ac.jp\/researchinfo\/result-en\/2022\/06\/20220623-01.html<\/p>\n\n\n\n

Learn More About <\/em><\/mark>Bioinformatics<\/mark><\/a><\/em>:<\/em><\/mark><\/strong><\/h2>\n\n\n\n
\n
\n

Top Bioinformatics Books<\/mark><\/a> <\/mark><\/a>\u2197<\/mark><\/a><\/strong><\/h3>\n\n\n\n

Learn more to get deeper insights into the field of bioinformatics.<\/p>\n<\/div>\n\n\n\n

\n

Top Free Online Bioinformatics Courses \u2197<\/mark><\/a><\/strong><\/h3>\n\n\n\n

Freely available courses to learn each and every aspect of bioinformatics<\/a>.<\/p>\n<\/div>\n\n\n\n

\n

Latest Bioinformatics <\/mark>Breakthroughs<\/mark><\/strong> \u2197<\/mark><\/a><\/strong><\/h3>\n\n\n\n

Stay updated with the latest discoveries in the field of bioinformatics.<\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

A research team from Nagoya University in Japan has created a 3-Dimensional computational simulation of the formation of the genome structure in the human cell nucleus. The model is expected to help in understanding cellular regulatory mechanisms and diseases like cancer that modify DNA. Because it influences DNA reading and replication, the three-dimensional shape of…<\/p>\n","protected":false},"author":3,"featured_media":6447,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":"","footnotes":""},"categories":[154,156,140],"tags":[981,982,977,979,603,980],"class_list":["post-6446","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bioinformatics","category-cancer-research","category-bioinformatics-news","tag-3-dimensional-computational-simulation","tag-3-dimensional-genome-structure","tag-chromatin","tag-hi-c-method","tag-liquid-liquid-phase-separation","tag-phase-separation"],"yoast_head":"\nApplying 3D Computational Simulation to Reveal the Secrets of the Genome Structure in the Human Cell Nucleus - CBIRT<\/title>\n<meta name=\"description\" content=\"Scientists created a 3-Dimensional computational simulation of the formation of the genome structure in the human cell nucleus.\" \/>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Applying 3D Computational Simulation to Reveal the Secrets of the Genome Structure in the Human Cell Nucleus\" \/>\n<meta property=\"og:description\" content=\"Scientists created a 3-Dimensional computational simulation of the formation of the genome structure in the human cell nucleus.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/cbirt.net\/staging\/applying-3d-computational-simulation-to-reveal-the-secrets-of-the-genome-structure-in-the-human-cell-nucleus\/\" \/>\n<meta property=\"og:site_name\" content=\"CBIRT\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/Centre.Bioinformatics.Research.Technology\" \/>\n<meta property=\"article:published_time\" content=\"2022-06-25T00:30:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-07-01T19:41:53+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/cbirt.net\/staging\/wp-content\/uploads\/2022\/06\/20220623_01_Prof.Sasai_.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1280\" \/>\n\t<meta property=\"og:image:height\" content=\"720\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Dr. Tamanna Anwar\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@CbirtDirector\" \/>\n<meta name=\"twitter:site\" content=\"@CbirtDirector\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Dr. Tamanna Anwar\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/cbirt.net\\\/staging\\\/applying-3d-computational-simulation-to-reveal-the-secrets-of-the-genome-structure-in-the-human-cell-nucleus\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/cbirt.net\\\/staging\\\/applying-3d-computational-simulation-to-reveal-the-secrets-of-the-genome-structure-in-the-human-cell-nucleus\\\/\"},\"author\":{\"name\":\"Dr. Tamanna Anwar\",\"@id\":\"https:\\\/\\\/cbirt.net\\\/staging\\\/#\\\/schema\\\/person\\\/80a42faa996bcd1d84a7ed35e7c2ff12\"},\"headline\":\"Applying 3D Computational Simulation to Reveal the Secrets of the Genome Structure in the Human Cell Nucleus\",\"datePublished\":\"2022-06-25T00:30:00+00:00\",\"dateModified\":\"2022-07-01T19:41:53+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/cbirt.net\\\/staging\\\/applying-3d-computational-simulation-to-reveal-the-secrets-of-the-genome-structure-in-the-human-cell-nucleus\\\/\"},\"wordCount\":704,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/cbirt.net\\\/staging\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/cbirt.net\\\/staging\\\/applying-3d-computational-simulation-to-reveal-the-secrets-of-the-genome-structure-in-the-human-cell-nucleus\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/cbirt.net\\\/staging\\\/wp-content\\\/uploads\\\/2022\\\/06\\\/20220623_01_Prof.Sasai_.jpg\",\"keywords\":[\"3-Dimensional Computational Simulation\",\"3-Dimensional Genome Structure\",\"Chromatin\",\"Hi-C Method\",\"Liquid-Liquid Phase Separation\",\"Phase Separation\"],\"articleSection\":[\"Bioinformatics\",\"Cancer Research\",\"News\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/cbirt.net\\\/staging\\\/applying-3d-computational-simulation-to-reveal-the-secrets-of-the-genome-structure-in-the-human-cell-nucleus\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/cbirt.net\\\/staging\\\/applying-3d-computational-simulation-to-reveal-the-secrets-of-the-genome-structure-in-the-human-cell-nucleus\\\/\",\"url\":\"https:\\\/\\\/cbirt.net\\\/staging\\\/applying-3d-computational-simulation-to-reveal-the-secrets-of-the-genome-structure-in-the-human-cell-nucleus\\\/\",\"name\":\"Applying 3D Computational Simulation to Reveal the Secrets of the Genome Structure in the Human Cell Nucleus - CBIRT\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/cbirt.net\\\/staging\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/cbirt.net\\\/staging\\\/applying-3d-computational-simulation-to-reveal-the-secrets-of-the-genome-structure-in-the-human-cell-nucleus\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/cbirt.net\\\/staging\\\/applying-3d-computational-simulation-to-reveal-the-secrets-of-the-genome-structure-in-the-human-cell-nucleus\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/cbirt.net\\\/staging\\\/wp-content\\\/uploads\\\/2022\\\/06\\\/20220623_01_Prof.Sasai_.jpg\",\"datePublished\":\"2022-06-25T00:30:00+00:00\",\"dateModified\":\"2022-07-01T19:41:53+00:00\",\"description\":\"Scientists created a 3-Dimensional computational simulation of the formation of the genome structure in the human cell nucleus.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/cbirt.net\\\/staging\\\/applying-3d-computational-simulation-to-reveal-the-secrets-of-the-genome-structure-in-the-human-cell-nucleus\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/cbirt.net\\\/staging\\\/applying-3d-computational-simulation-to-reveal-the-secrets-of-the-genome-structure-in-the-human-cell-nucleus\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/cbirt.net\\\/staging\\\/applying-3d-computational-simulation-to-reveal-the-secrets-of-the-genome-structure-in-the-human-cell-nucleus\\\/#primaryimage\",\"url\":\"https:\\\/\\\/cbirt.net\\\/staging\\\/wp-content\\\/uploads\\\/2022\\\/06\\\/20220623_01_Prof.Sasai_.jpg\",\"contentUrl\":\"https:\\\/\\\/cbirt.net\\\/staging\\\/wp-content\\\/uploads\\\/2022\\\/06\\\/20220623_01_Prof.Sasai_.jpg\",\"width\":1280,\"height\":720,\"caption\":\"genome structure, computer simulation\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/cbirt.net\\\/staging\\\/applying-3d-computational-simulation-to-reveal-the-secrets-of-the-genome-structure-in-the-human-cell-nucleus\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/cbirt.net\\\/staging\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Applying 3D Computational Simulation to Reveal the Secrets of the Genome Structure in the Human Cell Nucleus\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/cbirt.net\\\/staging\\\/#website\",\"url\":\"https:\\\/\\\/cbirt.net\\\/staging\\\/\",\"name\":\"CBIRT\",\"description\":\"Centre of Bioinformatics Research & Technology\",\"publisher\":{\"@id\":\"https:\\\/\\\/cbirt.net\\\/staging\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/cbirt.net\\\/staging\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/cbirt.net\\\/staging\\\/#organization\",\"name\":\"Centre of Bioinformatics Research & Technology\",\"alternateName\":\"CBIRT\",\"url\":\"https:\\\/\\\/cbirt.net\\\/staging\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/cbirt.net\\\/staging\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/cbirt.net\\\/staging\\\/wp-content\\\/uploads\\\/2026\\\/09\\\/CBIRT-Logo-Transparent.png\",\"contentUrl\":\"https:\\\/\\\/cbirt.net\\\/staging\\\/wp-content\\\/uploads\\\/2026\\\/09\\\/CBIRT-Logo-Transparent.png\",\"width\":403,\"height\":403,\"caption\":\"Centre of Bioinformatics Research & Technology\"},\"image\":{\"@id\":\"https:\\\/\\\/cbirt.net\\\/staging\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/Centre.Bioinformatics.Research.Technology\",\"https:\\\/\\\/x.com\\\/CbirtDirector\",\"https:\\\/\\\/www.linkedin.com\\\/in\\\/cbirt\\\/\",\"https:\\\/\\\/www.instagram.com\\\/cbirtdirector\\\/\",\"https:\\\/\\\/www.reddit.com\\\/user\\\/cbirt_\"],\"description\":\"Centre of Bioinformatics Research & Technology (CBIRT) is an ISO 9001:2015 certified, MSME-registered bioinformatics training and research organization based in India. CBIRT provides hands-on training programs in computational biology and bioinformatics \u2014 including genomics, network biology, drug discovery, and cancer data analysis \u2014 alongside OMICS data analysis services and science communication for the global bioinformatics community.\",\"email\":\"info@cbirt.net\",\"telephone\":\"+91-6398142849\",\"legalName\":\"Centre of Bioinformatics Research and Technology\",\"numberOfEmployees\":{\"@type\":\"QuantitativeValue\",\"minValue\":\"1\",\"maxValue\":\"10\"}},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/cbirt.net\\\/staging\\\/#\\\/schema\\\/person\\\/80a42faa996bcd1d84a7ed35e7c2ff12\",\"name\":\"Dr. Tamanna Anwar\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/5d2f8d79c151b5b9e5965d78b9246f1e558351590219594e7068849ac381ca97?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/5d2f8d79c151b5b9e5965d78b9246f1e558351590219594e7068849ac381ca97?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/5d2f8d79c151b5b9e5965d78b9246f1e558351590219594e7068849ac381ca97?s=96&d=mm&r=g\",\"caption\":\"Dr. Tamanna Anwar\"},\"description\":\"Dr. Tamanna Anwar is a Scientist and Co-founder of the Centre of Bioinformatics Research and Technology (CBIRT). She is a passionate bioinformatics scientist and a visionary entrepreneur. Dr. Tamanna has worked as a Young Scientist at Jawaharlal Nehru University, New Delhi. She has also worked as a Postdoctoral Fellow at the University of Saskatchewan, Canada. She has several scientific research publications in high-impact research journals. Her latest endeavor is the development of a platform that acts as a one-stop solution for all bioinformatics related information as well as developing a bioinformatics news portal to report cutting-edge bioinformatics breakthroughs.\",\"sameAs\":[\"https:\\\/\\\/cbirt.net\\\/staging\"],\"honorificPrefix\":\"Dr.\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Applying 3D Computational Simulation to Reveal the Secrets of the Genome Structure in the Human Cell Nucleus - CBIRT","description":"Scientists created a 3-Dimensional computational simulation of the formation of the genome structure in the human cell nucleus.","robots":{"index":"noindex","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"og_locale":"en_US","og_type":"article","og_title":"Applying 3D Computational Simulation to Reveal the Secrets of the Genome Structure in the Human Cell Nucleus","og_description":"Scientists created a 3-Dimensional computational simulation of the formation of the genome structure in the human cell nucleus.","og_url":"https:\/\/cbirt.net\/staging\/applying-3d-computational-simulation-to-reveal-the-secrets-of-the-genome-structure-in-the-human-cell-nucleus\/","og_site_name":"CBIRT","article_publisher":"https:\/\/www.facebook.com\/Centre.Bioinformatics.Research.Technology","article_published_time":"2022-06-25T00:30:00+00:00","article_modified_time":"2022-07-01T19:41:53+00:00","og_image":[{"width":1280,"height":720,"url":"https:\/\/cbirt.net\/staging\/wp-content\/uploads\/2022\/06\/20220623_01_Prof.Sasai_.jpg","type":"image\/jpeg"}],"author":"Dr. Tamanna Anwar","twitter_card":"summary_large_image","twitter_creator":"@CbirtDirector","twitter_site":"@CbirtDirector","twitter_misc":{"Written by":"Dr. Tamanna Anwar","Est. reading time":"4 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/cbirt.net\/staging\/applying-3d-computational-simulation-to-reveal-the-secrets-of-the-genome-structure-in-the-human-cell-nucleus\/#article","isPartOf":{"@id":"https:\/\/cbirt.net\/staging\/applying-3d-computational-simulation-to-reveal-the-secrets-of-the-genome-structure-in-the-human-cell-nucleus\/"},"author":{"name":"Dr. Tamanna Anwar","@id":"https:\/\/cbirt.net\/staging\/#\/schema\/person\/80a42faa996bcd1d84a7ed35e7c2ff12"},"headline":"Applying 3D Computational Simulation to Reveal the Secrets of the Genome Structure in the Human Cell Nucleus","datePublished":"2022-06-25T00:30:00+00:00","dateModified":"2022-07-01T19:41:53+00:00","mainEntityOfPage":{"@id":"https:\/\/cbirt.net\/staging\/applying-3d-computational-simulation-to-reveal-the-secrets-of-the-genome-structure-in-the-human-cell-nucleus\/"},"wordCount":704,"commentCount":0,"publisher":{"@id":"https:\/\/cbirt.net\/staging\/#organization"},"image":{"@id":"https:\/\/cbirt.net\/staging\/applying-3d-computational-simulation-to-reveal-the-secrets-of-the-genome-structure-in-the-human-cell-nucleus\/#primaryimage"},"thumbnailUrl":"https:\/\/cbirt.net\/staging\/wp-content\/uploads\/2022\/06\/20220623_01_Prof.Sasai_.jpg","keywords":["3-Dimensional Computational Simulation","3-Dimensional Genome Structure","Chromatin","Hi-C Method","Liquid-Liquid Phase Separation","Phase Separation"],"articleSection":["Bioinformatics","Cancer Research","News"],"inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/cbirt.net\/staging\/applying-3d-computational-simulation-to-reveal-the-secrets-of-the-genome-structure-in-the-human-cell-nucleus\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/cbirt.net\/staging\/applying-3d-computational-simulation-to-reveal-the-secrets-of-the-genome-structure-in-the-human-cell-nucleus\/","url":"https:\/\/cbirt.net\/staging\/applying-3d-computational-simulation-to-reveal-the-secrets-of-the-genome-structure-in-the-human-cell-nucleus\/","name":"Applying 3D Computational Simulation to Reveal the Secrets of the Genome Structure in the Human Cell Nucleus - CBIRT","isPartOf":{"@id":"https:\/\/cbirt.net\/staging\/#website"},"primaryImageOfPage":{"@id":"https:\/\/cbirt.net\/staging\/applying-3d-computational-simulation-to-reveal-the-secrets-of-the-genome-structure-in-the-human-cell-nucleus\/#primaryimage"},"image":{"@id":"https:\/\/cbirt.net\/staging\/applying-3d-computational-simulation-to-reveal-the-secrets-of-the-genome-structure-in-the-human-cell-nucleus\/#primaryimage"},"thumbnailUrl":"https:\/\/cbirt.net\/staging\/wp-content\/uploads\/2022\/06\/20220623_01_Prof.Sasai_.jpg","datePublished":"2022-06-25T00:30:00+00:00","dateModified":"2022-07-01T19:41:53+00:00","description":"Scientists created a 3-Dimensional computational simulation of the formation of the genome structure in the human cell nucleus.","breadcrumb":{"@id":"https:\/\/cbirt.net\/staging\/applying-3d-computational-simulation-to-reveal-the-secrets-of-the-genome-structure-in-the-human-cell-nucleus\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/cbirt.net\/staging\/applying-3d-computational-simulation-to-reveal-the-secrets-of-the-genome-structure-in-the-human-cell-nucleus\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/cbirt.net\/staging\/applying-3d-computational-simulation-to-reveal-the-secrets-of-the-genome-structure-in-the-human-cell-nucleus\/#primaryimage","url":"https:\/\/cbirt.net\/staging\/wp-content\/uploads\/2022\/06\/20220623_01_Prof.Sasai_.jpg","contentUrl":"https:\/\/cbirt.net\/staging\/wp-content\/uploads\/2022\/06\/20220623_01_Prof.Sasai_.jpg","width":1280,"height":720,"caption":"genome structure, computer simulation"},{"@type":"BreadcrumbList","@id":"https:\/\/cbirt.net\/staging\/applying-3d-computational-simulation-to-reveal-the-secrets-of-the-genome-structure-in-the-human-cell-nucleus\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/cbirt.net\/staging\/"},{"@type":"ListItem","position":2,"name":"Applying 3D Computational Simulation to Reveal the Secrets of the Genome Structure in the Human Cell Nucleus"}]},{"@type":"WebSite","@id":"https:\/\/cbirt.net\/staging\/#website","url":"https:\/\/cbirt.net\/staging\/","name":"CBIRT","description":"Centre of Bioinformatics Research & Technology","publisher":{"@id":"https:\/\/cbirt.net\/staging\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/cbirt.net\/staging\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/cbirt.net\/staging\/#organization","name":"Centre of Bioinformatics Research & Technology","alternateName":"CBIRT","url":"https:\/\/cbirt.net\/staging\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/cbirt.net\/staging\/#\/schema\/logo\/image\/","url":"https:\/\/cbirt.net\/staging\/wp-content\/uploads\/2026\/09\/CBIRT-Logo-Transparent.png","contentUrl":"https:\/\/cbirt.net\/staging\/wp-content\/uploads\/2026\/09\/CBIRT-Logo-Transparent.png","width":403,"height":403,"caption":"Centre of Bioinformatics Research & Technology"},"image":{"@id":"https:\/\/cbirt.net\/staging\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/Centre.Bioinformatics.Research.Technology","https:\/\/x.com\/CbirtDirector","https:\/\/www.linkedin.com\/in\/cbirt\/","https:\/\/www.instagram.com\/cbirtdirector\/","https:\/\/www.reddit.com\/user\/cbirt_"],"description":"Centre of Bioinformatics Research & Technology (CBIRT) is an ISO 9001:2015 certified, MSME-registered bioinformatics training and research organization based in India. CBIRT provides hands-on training programs in computational biology and bioinformatics \u2014 including genomics, network biology, drug discovery, and cancer data analysis \u2014 alongside OMICS data analysis services and science communication for the global bioinformatics community.","email":"info@cbirt.net","telephone":"+91-6398142849","legalName":"Centre of Bioinformatics Research and Technology","numberOfEmployees":{"@type":"QuantitativeValue","minValue":"1","maxValue":"10"}},{"@type":"Person","@id":"https:\/\/cbirt.net\/staging\/#\/schema\/person\/80a42faa996bcd1d84a7ed35e7c2ff12","name":"Dr. Tamanna Anwar","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/5d2f8d79c151b5b9e5965d78b9246f1e558351590219594e7068849ac381ca97?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/5d2f8d79c151b5b9e5965d78b9246f1e558351590219594e7068849ac381ca97?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/5d2f8d79c151b5b9e5965d78b9246f1e558351590219594e7068849ac381ca97?s=96&d=mm&r=g","caption":"Dr. Tamanna Anwar"},"description":"Dr. Tamanna Anwar is a Scientist and Co-founder of the Centre of Bioinformatics Research and Technology (CBIRT). She is a passionate bioinformatics scientist and a visionary entrepreneur. Dr. Tamanna has worked as a Young Scientist at Jawaharlal Nehru University, New Delhi. She has also worked as a Postdoctoral Fellow at the University of Saskatchewan, Canada. She has several scientific research publications in high-impact research journals. Her latest endeavor is the development of a platform that acts as a one-stop solution for all bioinformatics related information as well as developing a bioinformatics news portal to report cutting-edge bioinformatics breakthroughs.","sameAs":["https:\/\/cbirt.net\/staging"],"honorificPrefix":"Dr."}]}},"post_mailing_queue_ids":[],"_links":{"self":[{"href":"https:\/\/cbirt.net\/staging\/wp-json\/wp\/v2\/posts\/6446","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cbirt.net\/staging\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cbirt.net\/staging\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cbirt.net\/staging\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/cbirt.net\/staging\/wp-json\/wp\/v2\/comments?post=6446"}],"version-history":[{"count":0,"href":"https:\/\/cbirt.net\/staging\/wp-json\/wp\/v2\/posts\/6446\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cbirt.net\/staging\/wp-json\/wp\/v2\/media\/6447"}],"wp:attachment":[{"href":"https:\/\/cbirt.net\/staging\/wp-json\/wp\/v2\/media?parent=6446"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cbirt.net\/staging\/wp-json\/wp\/v2\/categories?post=6446"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cbirt.net\/staging\/wp-json\/wp\/v2\/tags?post=6446"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}