Sr Computational Scientist – Omics Data

    Sr Computational Scientist - OMICS Data at MD Anderson Cancer Center

    Website MD Anderson Cancer Center

    Job Profile: Sr Computational Scientist – Omics Data

    Requisition #:154364

    Department: Genomic Med Rsch Department

    Location: Houston, TX

    Posted Date: 11/15/2022

    The Wang Laboratory at MD Anderson Cancer Center is a computational biology research lab. We apply innovative bioinformatics approaches to deeply profile tumor cells and cells of the tumor microenvironment in order to identify tumor cell intrinsic and microenvironmental factors driving tumor phenotypic heterogeneity and evolution, and better understand the mechanisms underlying early tumorigenesis, disease progression, and the development of therapy resistance.

    We are seeking a highly motivated and enthusiastic senior computational scientist (Sr Computational Scientist – Omics Data) who will help develop and maintain the analytical pipelines for processing and analysis of single cell and spatial multi-omics datasets. A primary responsibility of this position is to conduct bioinformatics analysis and develop novel analytical methods and tools as needed to address key biological questions.

    Key Functions

    * Participate in the design of computational experiments, data analysis and results interpretation.

    * Adopt and evaluate existing methods and tools, establish and maintain computational infrastructure and analytic pipelines in the lab.

    * Develop computational methods as needed for integrative analysis of single cell and spatial multiomics data.

    * Conduct computational analysis of bulk, single cell and spatial multiomics data, and perform high-dimensional, multimodal data integration.

    * Meets with collaborators to discuss projects and communicate results.

    * Work with teams of individuals to integrate data / metadata and assist postdocs and students in the lab in analyzing and resolving analysis issues as needed.

    * Assist with manuscript and grant preparation and present results during lab meetings, at department and institutional meetings and seminars, and at appropriate scientific conferences.

    * Employ safe laboratory practices and help to maintain current and accurate records of research data.

    * Other duties as assigned and inclusive of: attend collaborator meetings and team working group meetings; prioritize and manage multiple projects in a timely and resource-effective manner; read literatures, gather relevant information systematically, and confers with supervisor regarding new procedures; organize data on laboratory servers; Assist with data/code submission, and distribute methods and codes to the scientific community, etc.

    Core Competencies

    Self-Motivation (Operative/Team Support): Set high standards of performance; pursue goals with energy and persistence; drive for results and achievement.
    * Use standards set by management. Take ownership for actions. Continually meet departmental goals.

    Technical/Functional Expertise (Operative/Team Support):

    * Demonstrate technical proficiency required to do the job; possess up-to-date knowledge in the profession; provide technical expertise to others.
    * Apply basic technical/functional knowledge to complete work. Meet essential position requirements.

    Analytical Thinking (Operative/Team Support):

    * Gather relevant information; systematically break down problems into simple components; make sound decisions.
    * Recognize simple cause and effect relationships. Diagnose problems by breaking them down into simple tasks or activities.

    Team with Others (Independent Contributor):

    Encourage collaboration and input from all team members; value the contributions of all team members; Balance individual and team goals.
    * Support and show respect to team members. Recognize how individual actions affect the team.
    * Model team qualities, i.e. respect, helpfulness and coping. Support team decisions once they are made and help to implement.

    Ideal Candidate will have:

    •With a Ph.D. degree in computer science, quantitative science, bioinformatics, biostatistics, or a related field.
    •With experience in processing and analyzing single-cell multi-omics, and/or spatial omics data;
    •With three-year experience in scientific software development;
    •Proficiency in at least one programming languages such as R, Python, JAVA, etc.
    •Experience with Linux server administration and data management and cloud computing is required.
    •Must be honest, highly motivated, reliable, responsible, well organized and a careful record
    keeper with good attention to details.
    •Excellent written and verbal communication skills are required as well as the ability to work well in a collaborative and interdisciplinary team environment.
    •Strong attention to detail, multi-tasking and a willingness to learn new technologies is encouraged.

    Other duties as required.

    EDUCATION:
    Required: Bachelor’s degree with a concentration in Science, Engineering or related field.

    Preferred: Master’s degree or PhD computer science, quantitative science, bioinformatics, biostatistics, or a related field.

    EXPERIENCE:
    Required: Nine years of experience in scientific software programming with a concentration in scientific computing. With Master’s degree, seven years experience required. With PhD, five years of experience required.

    Preferred: Ideal Candidate will have:
    •With a Ph.D. degree in computer science, quantitative science, bioinformatics, biostatistics, or a related field.
    •With experience in processing and analyzing single-cell multi-omics, and/or spatial omics data;
    •With three-year experience in scientific software development;
    •Proficiency in at least one programming languages such as R, Python, JAVA, etc.
    •Experience with Linux server administration and data management and cloud computing is required.
    •Must be honest, highly motivated, reliable, responsible, well organized and a careful record keeper with good attention to details.
    •Excellent written and verbal communication skills are required as well as the ability to work well in a collaborative and interdisciplinary team environment.
    •Strong attention to detail, multi-tasking and a willingness to learn new technologies is encouraged.

    It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html

    Additional Information

    • Requisition ID: 154364
    • Employment Status: Full-Time
    • Employee Status: Regular
    • Work Week: Days
    • Minimum Salary: US Dollar (USD) 84,500
    • Midpoint Salary: US Dollar (USD) 105,500
    • Maximum Salary : US Dollar (USD) 126,500
    • FLSA: exempt and not eligible for overtime pay
    • Fund Type: Soft
    • Work Location: Hybrid Onsite/Remote
    • Pivotal Position: Yes
    • Referral Bonus Available?: Yes
    • Relocation Assistance Available?: Yes
    • Science Jobs: Yes

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