Website Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC)
Profile: Postdoctoral position in genomics
Company: Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC)
Posted on: 04-04-22
A postdoctoral position in genomics is available to work at the Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC) in Strasbourg, France, on a project led by Anaïs Bardet in the team of Nacho Molina. We study the regulation of gene expression by transcription factors and their role in determining cellular identity and disease states using both experimental and computational strategies. The project aims to study transcription factor binding and their sensitivity to DNA methylation and nucleosome positioning and will involve collaboration with computational members of our team.
We are looking for an enthusiastic and motivated candidate with a PhD in molecular biology or related discipline and a good publication record. Previous experience with cell culture (mouse embryonic stem cells), genome editing (CRISPR/Cas9) and genomic protocols (ChIP-seq, RNA-seq, Bisulfite-sequencing) is preferable. Good communication skills and ability to work in an interdisciplinary team are essential.
The IGBMC is one of the main European centers in Biomedical research and offers a highly stimulating multidisciplinary research environment with cutting edge technological platforms.
Applications including a cover letter and a CV should be sent by email to firstname.lastname@example.org as one PDF document. Possible starting date: June 1st 2022
Detilleux D*, Spill YG*, Balaramane D, Weber M, Bardet AF. Pan-cancer predictions of transcription factors mediating aberrant DNA methylation. Epigenetics & Chromatin (2022) 15:10 *co-first author
Leporcq C, Spill Y, Balaramane D, Toussaint C, Weber M, Bardet AF. TFmotifView: a webserver for the visualization of transcription factor motifs in genomic regions. Nucleic Acid Research (2020) 48:W208-W217
Héberlé É, Bardet AF. Sensitivity of transcription factors to DNA methylation. Essays Biochem. (2019) 63(6):727-741
Domcke S*, Bardet AF*, Ginno P, Hartl D, Burger L, Schübeler D. Competition between DNA methylation and transcription factors determines binding of NRF1. Nature (2015) 528(7583):575-9 *co-first author.
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